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Supplement J Med Sci, Volume 48, No. 4, 2016 October

18

Proposed organization of family cancer

clinics in Indonesia

Kunta Setiaji*

Division of Surgical Oncology, Department of Surgery Universitas Gadjah Mada

DOI: http://dx.doi.org/10.19106/JMedScieSup0048042016016

ABSTRACT

Around 10-15% of breast cancers are associated hereditary and/or familial predisposition. Familial breast cancer is deined as the case that occurs in two or more irst degree relatives within a nuclear pedigree (irst or second degree

relatives). Hereditary and familial cancer display different characteristics in pathological features, clinical course, response to treatment, and outcome.

Therefore, speciic consultation and treatment need to be addressed to patients

with hereditary or familial predisposition, e.g. the need for rigorous surveillance and preventive treatment including preventive surgery. Cancer clinical genetic service is not yet formally available in daily clinical practice in Indonesia.

Surgeons usually become the irst medical specialist to see cancer patients with

familial predisposition, thus they have to integrate clinical cancer genetics service under Family Cancer Clinic (FCC). Clinical genetics service within FCC consists of several step-wise tasks, including assessment of personal and family history of cancer, personalized cancer risk assessment, review of medical and family history, individual cancer screening and surveillance recommendations, genetic

testing if necessary, discussion of beneits and limitations of genetic test, cancer

risk reduction options, preventive strategies, and opportunity to participate in research as well as clinical trial. Nation-wide network for FCC is important to facilitate knowledge and skill sharing in order to perform cancer genetics service. Ability to perform genetic test and interpretation in Indonesia is also required.

Keywords: familial cancer, hereditary cancer, genetic counseling, family cancer clinics

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