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References

1. Avis NE, Pian-Smith MC. Acupuncture for hot flashes. Menopause 2007; 14(1): 10-3.

2. Cohen SM, Rousseau ME, Carey BL. Can acupuncture ease the symptoms of menopause? Holist Nurs Pract 2003; 17(6): 295-9.

3. Lindh-Astrand L, Nedstrand E, Wyon Y, Hammar M. Vasomotor symptoms and quality of life in previously sedentary postmenopausal women randomised to physical activity or estrogen therapy. Maturitas 2004; 48(2):

97-105.

4. Whiteman MK, Staropoli CA, Langenberg PW, McCarter RJ, Kjerulff KH, Flaws JA. Smoking, body mass, and hot flashes in midlife women. Obstet Gynecol 2003; 101(2):264-272.

5. Schwingl PJ, Hulka BS, Harlow SD. Risk factors for menopausal hot flashes. Obstet Gynecol 1994; 84(1): 29-34.

6. Blumberg G, Kaplan B, Rabinerson D, Goldman GA, Kitai E, Neri A. Women's attitudes towards menopause and hormone replacement therapy. Int J Gynaecol Obstet 1996; 54(3): 271-7.

7. Kronenberg F. Hot flashes: phenomenology, quality of life, and search for treatment options. Exp Gerontol 1994;

29(3-4): 319-36.

8. Borud EK, Alraek T, White A, Fonnebo V, Grimsgaard S. The effect of TCM acupuncture on hot flushes among menopausal women (ACUFLASH) study: a study protocol of an ongoing multi-centre randomised controlled clinical trial. BMC Complement Altern Med 2007; 7: 6.

9. Dantas SM. Menopausal symptoms and alternative medicine - Evaluation by ambulatory monitoring. Prim Care Obstet Gynecol 1999; 6(6): 177-224.

10. Wyon Y, Lindgren R, Lunderberg T, Hammar M. Effects of acupuncture on climacteric vasomotor symptoms, quality of life, and urinary excretion of neuropeptides among postmenopausal women. Menopause 1995; 2(1): 3-12.

11. Kronenberg F, Fugh-Berman A. Complementary and alternative medicine for menopausal symptoms: a review of randomized, controlled trials. Ann Intern Med 2002; 137(10): 805-13.

12. Andersson S, Lundeberg T. Acupuncture--from empiricism to science: functional background to acupuncture effects in pain and disease. Med Hypotheses 1995; 45(3): 271-81.

13. Han JS. Acupuncture and endorphins: Mini-review. Neuroscience letters 2004; 361(1-3): 258-61.

14. Shoupe D, Lobo RA. Endogenous opioids in the menopause. 2nd ed. New York: Thieme Medical Publishers Inc;

1987. p. 199-206.

15. Tepper R, Neri A, Kaufman H, Schoenfeld A, Ovadia J. Menopausal hot flushes and plasma beta-endorphins.

Obstet Gynecol 1987; 70(2): 150-2.

16. Sandberg M, Wijma K, Wyon Y, Nedstrand E, Hammar M. Effects of electro-acupuncture on psychological distress in postmenopausal women. Complement Ther Med 2002; 10(3): 161-9.

17. Cohen FJ, Lu Y. Characterization of hot flashes reported by healthy postmenopausal women receiving raloxifene or placebo during osteoporosis prevention trials. Maturitas 2000; 34(1): 65-73.

18. Nir Y, Huang MI, Schnyer R, Chen B, Manber R. Acupuncture for postmenopausal hot flashes. Maturitas 2007;

56(4): 383-95.

19. Vincent A, Barton DL, Mandrekar JN, Cha SS, Zais T, Wahner-Roedler DL, et al. Acupuncture for hot flashes: a randomized, sham-controlled clinical study. Menopause 2007; 14(1): 45-52.

20. Nedstrand E, Wijma K, Wyon Y, Hammar M. Vasomotor symptoms decrease in women with breast cancer randomized to treatment with applied relaxation or electro-acupuncture: a preliminary study. Climacteric 2005;

8(3): 243-50.

21. Gould D, Goldstone L, Gammon J, Kelly D, Maidwell A. Establishing the validity of pressure ulcer risk assessment scales: a novel approach using illustrated patient scenarios. Int J Nurs Stud 2002; 39(2): 215-28.

22. Brich S. Controlling for non-specific effects of acupuncture in clinical trials. Clin Acupunct Oriental Med 2003;

4(2-3): 59-70.

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23. Sherman KJ, Hogeboom CJ, Cherkin DC, Deyo RA. Description and validation of a noninvasive placebo acupuncture procedure. J Altern Complement Med 2002; 8(1): 11-9.

24. Hammerschlag R. Methodological and ethical issues in clinical trials of acupuncture. J Altern Complement Med 1998; 4(2): 159-71.

25. Cho SH, Whang WW. Acupuncture for vasomotor menopausal symptoms: a systematic review. Menopause 2009; 16(5):1065-73.

26. Navidi AA. Principles of basic and clinical of acupuncture. 1st ed. Tehran: Teimoor Zadeh Publication; 2002. p.

86-170. [In Persian].

27. Han JS, Chen XH, Sun SL, Xu XJ, Yuan Y, Yan SC, et al. Effect of low- and high-frequency TENS on Met- enkephalin-Arg-Phe and dynorphin A immunoreactivity in human lumbar CSF. Pain 1991; 47(3): 295-8.

28. Hammar M, Frisk J, Grimas O, Hook M, Spetz AC, Wyon Y. Acupuncture treatment of vasomotor symptoms in men with prostatic carcinoma: a pilot study. J Urol 1999; 161(3): 853-6.

29. Freedman RR, Woodward S. Behavioral treatment of menopausal hot flushes: evaluation by ambulatory monitoring. Am J Obstet Gynecol 1992; 167(2): 436-9.

30. MacLennan A, Lester S, Moore V. Oral oestrogen replacement therapy versus placebo for hot flushes. Cochrane Database Syst Rev 2001; 4(1): CD002978.

31. Ganz PA, Greendale GA, Petersen L, Zibecchi L, Kahn B, Belin TR. Managing menopausal symptoms in breast cancer survivors: results of a randomized controlled trial. J Natl Cancer Inst 2000; 92(13): 1054-64.

32. Han KK, Soares JM, Jr., Haidar MA, de Lima GR, Baracat EC. Benefits of soy isoflavone therapeutic regimen on menopausal symptoms. Obstet Gynecol 2002; 99(3): 389-94.

33. Hammar M, Ekblad S, Lonnberg B, Berg G, Lindgren R, Wyon Y. Postmenopausal women without previous or current vasomotor symptoms do not flush after abruptly abandoning estrogen replacement therapy. Maturitas 1999; 31(2): 117-22.

34. Dong H, Ludicke F, Comte I, Campana A, Graff P, Bischof P. An exploratory pilot study of acupuncture on the quality of life and reproductive hormone secretion in menopausal women. J Altern Complement Med 2001; 7(6):

651-8.

35. Chen BY. Acupuncture normalizes dysfunction of hypothalamic-pituitary-ovarian axis. Acupunct Electrother Res 1997; 22(2): 97-108.

36. Shen X, Du Y, Yan L, Xia Y, Yan H, Han G, et al. Acupuncture for treatment of climacteric syndrome-a report of 35 cases. J Tradit Chin Med 2005; 25(1): 3-6.

37. Anderson D, Yoshizawa T, Gollschewski S, Atogami F, Courtney M. Menopause in Australia and Japan: effects of country of residence on menopausal status and menopausal symptoms. Climacteric 2004; 7(2): 165-74.

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* This research is registered in Iranian Registry of Clinical Trials by IRCT138901263719N1 code.

1Corresponding Author; Lecturer, Department of Midwifery, Kerman Branch, Islamic Azad University, Kerman, Iran.

Email: [email protected]

2Assistant Professor, Department of Cardiology, Kerman University of Medical Sciences, Kerman, Iran.

Abstract Original Article

The effects of electro-acupuncture in postmenopausal women with hot flashes*

A. Foroud1, A. Foroud2, S. Mehdipour3

Background and Aim: Hot flashes are the commonest complaint of postmenopausal women. Because of the side effects of hormone therapy, alternatives treatment methods, such as acupuncture, are used to control hot flashes. Therefore, the present study aimed to evaluate the effects of electro-acupuncture on hot flashes in postmenopausal women.

Materials and Methods: In this randomized, placebo-controlled trial, 41 postmenopausal women with hot flashes were divided to experimental and control groups. For experimental group, the electro- acupuncture was carried out; but in control group, needles taped to the skin in the same of acupoint and did not pass any electricity. The treatment period was 10 weeks; then patients were followed up for 3 months after the last treatment. Number of hot flashes was registered daily during 10 weeks and 3 months after the last treatment. The severity hot flashes were measured by visual analogue scale (VAS) after 2, 6 and 10 weeks of treatment and 3 months follow-up. Hormone levels (E2and FSH) were measured at the end of treatment and 3 months after the last treatment. Then chi-square, t-test, Mann-Whitney and Wilcoxon tests were used for data analysis.

Results: A significant difference was found in severity and number of hot flashes (except 2nd week) between two groups (P < 0.001). There were significant differences in the mean levels of FSH and E2

between groups at the end of treatment and 3 months after the last treatment (P < 0.001).

Conclusion: The findings of this study suggest that electro-acupunture is a suitable method of treatment for relief of hot flashes in postmenopausal women.

Keywords: Electro- acupuncture, Menopause, Hot flashes.

Journal of Birjand University of Medical Sciences 2010; 17(3): 169.

Received: 16.08.2008 Last Received: 19.07.2010 Accepted: 20.07.2010 Online Version: 20.10.2010

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