curiculum vitae

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ZOHAIR M. H. AL-MARZOUKI

Professor

Department of Clinical Biochemistry Faculty of Medicine & Allied Sciences

King Abdulaziz University Jeddah, Saudi Arabia

Name : Prof. Zohair M. H. Al-Marzouki Date of birth : December 25, 1956

Nationality : Saudi

Sex : Male

Marital Status : Married

Religion : Islam

Academic Qualifications:

B. Pharm. Sci. Faculty of Pharmacy, Cairo University, Egypt (1977) M. Sc. (Biochemistry), Vanderbilt University, USA (1981) Thesis Title: The Effect of Essential Fatty Acid Deficiency on Lipids of

Rat Sertoli and Germinal Cells.

Ph. D. (Biochemistry), Vanderbilt University, USA. (1983) Thesis Title: The Effect of Hypophysectomy and Testosterone Treatment

on the Composition and Metabolism of Testicular Lipids.

Position Held:

A Academic:

Professor, Clinical Biochemistry Department July 1998

Associate Professor, Clinical Biochemistry Department, 1989-June 1998 Faculty of Medicine & Allied Sciences, King Abdulaziz

University, Jeddah, Saudi Arabia.

Assistant Professor, Clinical Biochemistry Department, 1983-1989 Faculty of Medicine & Allied Sciences, King Abdulaziz

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Demonstrator (Teaching Assistant) Clinical Biochemistry 1977-1983 Department, Faculty of Medicine & Allied Sciences,

King Abdulaziz University, Jeddah, Saudi Arabia.

B Administrative:

Dean Faculty of Pharmacy 2001-2005

Member of the University Board 2001-2005

Member of the Deans Consulting Committee 2001-2005

Director, King Fahd Medical Research Center, KAU, Dec.97 - 2001

Jeddah, KSA.

Chairman, Department of Clinical Biochemistry, Faculty Sep96-2001 Of Medicine & Allied Sciences, King Abdulaziz

Board Secretary, Board of Directors for King Fahad April 96-2001 Medical Research Center, King Abdulaziz University,

Jeddah, Saudi Arabia.

Vice-Dean, Basic Medical Sciences, Faculty of May 1985-Aug.1987 Medicine & Allied Sciences, King Abdulaziz University,

Head of Drug Information Center, King Fahad Medical 1984-1986 Research Center, King Abdulaziz University,

Assistant Dean for Medical Technology, Faculty of Jan 1984-May 1985 Medicine & Allied Sciences, King Abdulaziz University,

Committees & Responsibilities:

Member of the permanent committee for Scientific Board. 2005-till now

Member of the Scientific promotion committee 2006-till now in the Faculty of Medicine

Member of the committee for evaluation of the 2006-till now extension for Saudi Academic teaching staff in Basic Science.

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Member of the Board of Directors for King Fahad 1996-Present Medical Research Center, King Abdulaziz University,

Member of the Post Graduate Committee in the 1996-Present Faculty of Medicine, King Abdulaziz University,

Member of Basic Science Sub-curriculum Committee, 1996-Present Faculty of Medicine, King Abdulaziz University,

Member of the Faculty Board, Faculty of Medicine 1984-1987 King Abdulaziz University, Jeddah, Saudi Arabia 1996-Present

Chairman, Basic Medical Science Curriculum Sub- 1985-1987 Committee, Faculty of Medicine, King Abdulaziz

Member Faculty Curriculum Committee, Faculty of 1985-1987 Medicine, King Abdulaziz University, Jeddah,

Saudi Arabia.

Chairman, Faculty Student Activity, Faculty of 1985-1987 Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.

Member, University Permanent Committee for Admission 1985-1987 And Registration, King Abdulaziz University,

Member, University Permanent Committee for Activity, 1985-1987 King Abdulaziz University, Jeddah, Saudi Arabia.

Member of Supervisory Committee of English Language 1985-1987 Center in the University, King Abdulaziz University,

Member, Committee for Interviewing New Students, 1983-Present Faculty of Medicine, King Abdulaziz University,

Member, Committee for Establishing, Faculty of 1986 Dentistry, King Abdulaziz University,

Member, Examination Committee, Faculty of Medicine, 1983-1990 King Abdulaziz University, Jeddah, Saudi Arabia.

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Teaching Activities:

Teaching Biochemistry course for students in the Second 1983-Present Year Medicine, Faculty of Medicine & Allied Sciences,

Teaching Biochemistry course for Second Year Medical 1983-Present Technology students, Faculty of Medicine & Allied Sciences,

Teaching Clinical Biochemistry courses for students 1985-Present In the Third and Fourth Year of Medicine, Faculty

of Medicine & Allied Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.

Teaching Clinical Biochemistry course for Second Year 1990-Present Dental students, Faculty of Medicine & Allied Sciences,

Teaching Clinical Chemistry Courses for Third Year 1985-Present Medical Technology students, Faculty of Medicine &

Allied Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.

Teaching Clinical Biochemistry course for second and 2005-Persent Fourth Year students (Boys & Girls), Faculty of Pharmacy.

Teaching Post-graduate courses in Clinical Biochemistry 1992-Present In Clinical Biochemistry, Faculty of Medicine &

Allied Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.

Taught Clinical Biochemistry for Graduate students 1992-1995 Preparing for the First Part Arab Board in

Obstetric and Gynecology, Jeddah, Saudi Arabia.

Taught a course of hyperlipedemia for Graduate 1990 Students enrolled in the Family Medicine

Program, Ministry of Health, Jeddah, Saudi Arabia.

Taught a course of hyperlipedemia and its dietary 1990-1993 Control for Graduate students of Home

Economic, King Abdulaziz University, Jeddah, Saudi Arabia.

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Scientific Activities:

Member of British Association of Clinical Biochemistry. 1984-Present

Examiner, Master thesis titled “Biochemical studies on 1411H Serum lipids of some selected Saudi groups” By Ms. Suhair

M. Ghoja, King Abdulaziz University, Jeddah, Saudi Arabia.

Examiner, Master thesis titled “Hormonal and Anabolic 1415H Changes in patients with renal failure” By Ms. Majda Shugdar,

Examiner, Master thesis titled “Comparative studies on 1416H Hexoseaminidase isoenzymes in the urine of some Saudi patients”

By Ms. Hala Salim Sunbul, King Abdulaziz University, Jeddah, Saudi Arabia.

Examiner, Master thesis titled “Activity of some oncogens 1417H in Saudi patients suffering from Leukemia” By Ms. Etimad Howait,

Supervisor, Master thesis titled “Plasma lipids in pregnant, 1417H Lactating diabetic and hypothyroid rats” By Ms. Majda B. Banama,

Co-supervisor Ph. D thesis titled “Antioxidant and Metal 1425-1427H Chelation properties of some Phenolic compounds in relation to the

prevention of UVA irradiated skin cell damage” by Sawsan Rahimuldin.

Research Activities:

o Principal Investigator of Research Project “Effect of Lipid peroxidation and Antioxidant status on Cardiovascular Disease in renal failure Saudi patients."

o Co-investigator of Research Project titled “Optimization of Efficiency and Evaluation of stability of insulin suppository Formulation.”

o Co-investigator of Research Project titled “Design and synthesis of some new 4(3H)-Quinazoline Analogs for Hypoglycemic activity.”

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o Co-investigator of Research Project titled “Synthesis of some new derivatives of cyclic imides for Hypolipidemic activity.”

o Principal Investigator of Research Project titled “Lipid Profiles in Sickle Cell Anemia and Thalassemias Patients” No. 121/416 Funded by King Abdulaziz University Research Council, Jeddah, Saudi Arabia.

o Co-Investigator of Research Project titled “Selenium Vitamin C and Vitamin E serum Levels of Saudi Arabian Population in the Western Region”, Funded by King Abdulaziz University Research Council, Jeddah, Saudi Arabia.

o Co-Investigator of Research Project titled “ Epidermal Cell-Cell Interaction: The Autocrine Regulation of Melanocytes in Normal and Vitiligenous Skin”

No. 120/417 Funded by King Abdulaziz University Research Council, Jeddah,

Saudi Arabia.

o Principal Investigator of Research Project titled “Biochemical Changes of Testicular Tissues of Mice Experimentally Infected With S. mansoni Prevalent in Saudi Arabia” No.023/411 Funded By King Abdulaziz University Research Council, Jeddah, Saudi Arabia (Completed).

o Co-Investigator of Research Project titled “A Study into the Prevention and Management of Heat Stroke” Grant No. AR-7-120 From King Abdulaziz City for Science and Technology, Saudi Arabia (Completed).

o Co-Investigator of Research Project titled : “ A comparative study of lipid profiles during pregnancy in healthy, diabetic and hypertensive women”.

o Principal Investigator of Research Project titled “Investigation Of Skin Surface Lipids (S.S.L) of Saudi Males and Females” Supported by grant No. AR-6-095 from King Abdulaziz City For Science and Technology, Saudi Arabia (Completed).

o Principal Investigator of Research Project titled “Serum, Liver and testicular lipid levels of Zinc deficient Rat”.

o Co-Investigator of Research Project titled “Effect of aging and diabetes in myocardial antioxidant enzymes activity on the rats”.

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LIST OF PUBLICATIONS

1. Marzouki, Z. M. H. Coniglio, J. G. Effect of essential fatty acid deficiency on lipids of rat Sertoli and Germinal cells. Biol. Reprod.

27:312. (1982).

2. Marzouki, Z. M. H., and Coniglio, J. G., The effect of hypophysectomy and Testosterone treatment on the composition and metabolism of testicular lipids. Lipids, 19#8, 609 (1984).

3. Marzouki, Z. M. H., Taha, A. M., and Gomma, K. S., variability in the composition of human skin surface lipids in tropical climates. J.

Tropical and Geographical Medicine. 39#4 (1987).

4. Marzouki, Z. M. H., A. M., and Gomma, K. S., Fatty acid profiles of sebaceous triglycerides by capillary gas chromatography with mass- selective detection. J. Chromatography. Biomed. Appl. 245, 11 (1988).

5. Coniglio, J. G., Marzouki, Z. M. H., and Sharp, J. Effect of hypophysectomy and hormone replacement on fatty acid elongation in isolated microsomes of rat testes. Archives of Andrology. 20:193.

(1988).

6. Marzouki, Z. M. H., and Tayeb, O. S., The effect of exposure to heat stroke conditions on serum phosphorus, calcium and parathormone.

The international symposium on work in hot environment and heat- related disorders. (1988).

7. Marzouki, Z. M. H., and Tayeb, O. S. Diagnostic significance of selected serum hormones in heat stroke. J. Med. Res. Institute.

(1988).

8. Marzouki, Z. M. H., and Tayeb, O. S. Diagnostic significance of selected serum enzymes in heat stroke. Arab. J. Lab. Med. 15#1, 93- 101. (1989).

9. Tayeb, O. S., Marzouki, Z. M. H., Tympanic thermometry in heat

stroke: Is it Justifiable? J. Physiol. Biochem. 7:255 (1989).

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10.Ajabnoor, M. A. M., Zawawi, T., H., Marzouki, K. M. H., Marzouki, Z. M. H., Serum Fructosamine: An index of intermediate term glycemic control in type II Saudi patients. Arab. J. Lab. Med.

15#1:33-40. (1989).

11.Tayeb, O. S., Marzouki, Z. M. H., Marzouki, S. A. , A study into prevention and management of heat stroke. Published by General Directorate of Research Grants Programs, King Abdul Aziz City for Science & Technology, Riyadh. (1989).

12.Marzouki, Z. M. H., Taha, A. M., Marzouki, K. M. H., and Zawawi, T. H. The effect of long-term exposure to petroleum products on the class composition of human skin surface lipids.

Arab. J. Lab. Med. 16#2:363-378 (1990). (P. author).

13.Ajabnoor, M. A. M., Zawawi, T. H., Marzouki, K. M. H., Marzouki, Z. M. H., Level of serum Fructosamine in Saudi diabetic patients.

Acta. Diabetotogica. Latina. 27:205-112 (1990).

14.Tayeb, O. S., Marzouki, Z. M. H. Effect of Dantrolene Pretreatment on Heat Stroke in Sheep. Pharmacological Research. 22#5:565-572 (1990).

15.Zawawi, T. H., Marzouki, K. M. H., Khan, A. S. Marzouki, Z. M.

H., Radioimmunometric Assay of TSH, an alternative to TRH test in Diagnosis of mild hyperthyroidism. Arab. J. Lab. Med. 17#1:199- 204 (1991).

16.Tayeb, O. S., Marzouki, Z. M. H., Effect of Naloxone Pretreatment on Heat Stroke in Sheep. Journal of Wilderness Medicine. 3:277-283 (1922).

17.Zawawi, T. H., Abdulwahab, S., Marzouki, K. M. H., Marzouki, Z.

M. H. Level of Fructosamine in thyroid disease. Annals of Saudi Medicine. Vol. 14#4: (1994).

18.Khoja, S. M., Marzouki, Z. M. H. Effect of vitamin C and E intake on plasma lipid concentrations in rats. Annals of Saudi Medicine.

Vol. 14#15: 371-374 (1994).

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19.Marzouki, Z. M. H., Amin, A. M. Changes in serum lipids of mice infected with Schistosoma mansoni prevalent in Saudi Arabia. E. J.

Parasitology. Vol. 27 # 2:419 – 429 (1997).

20.Marzouki, Z. M. H., Amin, A. M. The effect of Schistosoma mansoni infection on testicular lipids in mice. E. J. Parasitology.

Vol. 27 # 2 :581-595 (1997).

21.Banamah, M. B., Marzouki, Z. M. H., Al-Bar, O. A., Khoja, S. M.

Serum lipid levels of pregnant and lactating rats. Arab. J. Lab.

Med. 23 # 3:441-454 (1997).

22.Khoja, S. M., Banamah, M., MARZOUKI, Z.M.H., AL-BAR, O.A.

Serum Lipid Levels of Streptozotocin – induced diabetic pregnant rats. Medical Science Research (1998) 26:685-688.

23.Zailaie, M. Z., MARZOUKI, Z. M. H. Khoja, S.M., Damanhori, G.

A. Plasma and Red Blood Cell Membran Lipid Concentrations of B- Thalassimia Major Patients. The Arab J. Lab. Medicine. 27 (3): 323- 330 (2001).

24. Khoja, S. M., MARZOUKI, Z.M.H. Ashry, K.M., Hamdi, S.A.

Effect of Dietary Zinc deficiency of Rat Lipid Concentrations.

Saudi Medical J. 23 (1): 82-86 (2002).

25. Zailaie, M.Z., MARZOUKI, Z. M. H. Khoja, S.M., Plasma and red blood cells membrane lipid concentration of sickle cell disease patients. Saudi Medical J. 24 (4): 376-379 (2003).

26.Ehab A. Hosny., ALMARZOUKI, Z. M. H., Metwally, M. E. S., Souida, M. Y. S., Al Shaik, A. A. M. Evaluation of efficiency of insulin suppository formulation containing Sodium Solicylate or Sodium Cholate in insulin dependent diabetic patients. Boll. Chim.

Farmac. 142(8):361-366 (2003).

27.Al-Thakafy H.S., Khoja S.M., Al-Marzouki Z.M.H., Zailaie, M.Z.,

Al-Marzouki K.M.H. Alterations of erythrocyte free radical defense

system, heart tissue lipid peroxidation, and lipid concentration in

streptozotocin-induced diabetic rats under coenzyme Q

₁₀

supplementation. Saudi Medical J. Vol. 25 (12): 1824-1830 (2004)

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28.Gaber S.M., Khoja S.M., AbuelGassim O.A., Al-Marzouki Z.M.H., Al-Marzouki K.M.H., Al-Marzouki H.Z. Serum Lipid Level among Saudi School Children in Jeddah. The Arab J. Lab. Medicine. Under publication (2007).

29. El-Zahabi M.A., Bamanie F.H., Moustafa M., Al-Marzouki Z.M.H.

Design and Synthesis of some new 4(3H)-Quinazoline Analogs for Hypoglycemic activity. Under publication (2007).

30. El-Zahabi M.A., Gad L., Bamanie F.H., Al-Marzouki Z.M.H.

Synthesis of some new derivatives of Cyclic imides for hypolipidemic activity. Under publication (2007).

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