9891049.pdf

(1)

Erratum

Erratum to “ Molecular Responses of Human Retinal Cells to Infection with Dengue Virus ”

Jillian M. Carr,

¹

Liam M. Ashander ,

²

Julie K. Calvert,

¹

Yuefang Ma ,

²

Amanda Aloia,

³

Gustavo G. Bracho,

¹

Soon-Phaik Chee,

⁴

Binoy Appukuttan,

²

and Justine R. Smith

²

1Microbiology & Infectious Diseases, Flinders University School of Medicine, Rm 5D-316, 1 Flinders Drive, Bedford Park, Adelaide, SA 5042, Australia

2Eye & Vision Health, Flinders University School of Medicine, Rm 4E-431, 1 Flinders Drive, Bedford Park, Adelaide, SA 5042, Australia

3Flinders Centre for Innovation in Cancer, Flinders University School of Medicine, 1 Flinders Drive, Bedford Park, Adelaide, SA 5042, Australia

4Ocular Inﬂammation and Immunology Service, 11 Third Hospital Avenue, Singapore National Eye Centre, Singapore 168751

Correspondence should be addressed to Justine R. Smith; justine.smith@ﬂinders.edu.au Received 18 September 2018; Accepted 19 September 2018; Published 23 December 2018

Copyright © 2018 Jillian M. Carr et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

In the article titled

“Molecular Responses of Human Retinal

Cells to Infection with Dengue Virus,” [1] there was an error in the

ﬁrst graph in Figure 2(d). The numbers on they-axis

were incorrect. This error occurred during the production process. The correct

ﬁ

gure is shown below.

Hindawi

Mediators of Inﬂammation

Volume 2018, Article ID 9891049, 3 pages https://doi.org/10.1155/2018/9891049

(2)

15

10

5

p <0.01

p <0.05

Fold changeFold change

0 5 4 3 2 1 0

TNF-𝛼

IL-6

Mock DENV Mock DENVMock DENV

24 hr 48 hr 72 hr

Mock DENVMock DENVMock DENV

24 hr 48 hr 72 hr

(a)

24 hr48 hr72 hr

Mock DENV

(b)

dsRNA DENV-Ag Merge

MockDENV 48 hrDENV 24 hr

(c)

DENV RNA : PPIA

1.5

1.0

0.5

0.0

0 24 Time (hours)

48 72

pfu (mL)

10⁶ 10⁵ 10⁴ 10³ 10² 10¹

6 24

Time (hours)

48 72

(d)

Figure2: Infection of human retinal endothelial cells with DENV: viral strain = Mon601; multiplicity of infection = 1; evaluated time points postinoculation = 6, 24, 48, and 72 hours (hr). (a) Graphs showing relative expression of tumor necrosis factor-α(TNF-α) and interleukin-6 (IL-6) transcripts in DENV-infected endothelial cells versus mock-infected cells. Reference genes were glyceraldehyde-3-phosphate dehydrogenase and TATA-binding protein. Bars represent mean relative expression, with error bars showing standard deviation.n= 3 cultures/condition. Data were analyzed by two-tailed Student’st-test. (b) DENV-infected and mock-infected endothelial cells viewed by light microscopy. Original magniﬁcation = 100x. (c) DENV- and mock-infected endothelial cells immunolabeled to detect double-stranded RNA (dsRNA) and DENV antigen (Ag). Alexa Fluor 555 (red) and Alexa Fluor 488 (green) and with Hoechst 33342 nuclear counterstain (blue). Original magniﬁcation: 630x. (d) Graphs of copy number of DENV RNA for DENV-infected endothelial monolayers and plaque-forming units (pfu) for culture supernatant collected from infected cells.n= 3cultures/condition. Bars represent DENV RNA copy number (relative to cellular peptidylprolyl isomerase A (PPIA)) or mean pfu/mL, with error bars showing standard deviation.

2 Mediators of Inﬂammation

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References

[1] J. M. Carr, L. M. Ashander, J. K. Calvert et al., “Molecular responses of human retinal cells to infection with dengue virus,” Mediators of Inﬂammation, vol. 2017, Article ID 3164375, 16 pages, 2017.

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9891049.pdf

Erratum

Erratum to “ Molecular Responses of Human Retinal Cells to Infection with Dengue Virus ”

Jillian M. Carr,

Liam M. Ashander ,

Julie K. Calvert,

Yuefang Ma ,

Amanda Aloia,

Gustavo G. Bracho,

Soon-Phaik Chee,

Binoy Appukuttan,

and Justine R. Smith

In the article titled

Cells to Infection with Dengue Virus,” [1] there was an error in the

were incorrect. This error occurred during the production process. The correct

gure is shown below.

2 Mediators of Inﬂammation

References

Mediators of Inﬂammation 3

Stem Cells International

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Endocrinology

Disease Markers

Oncology

PPAR Research

The Scientific World Journal

Obesity

Behavioural Neurology Ophthalmology

Diabetes Research

AIDS

Parkinson’s Disease

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