http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TBB-3YCDPMG-N&_user=6763742&_coverDate=09%2F30%2F1995&_rdoc=1&_fmt=high&_orig=search&_sort=d&_doc anchor=&view=c&_searchStrId=1369838766&_rerunOrigin=scholar.google&_acct=C000070526&_versio n=1&_urlVersion=0&_userid=6763742&md5=e7e19e31cef579eb2d4d28c232f45930
Remarkable increase of peroxisomes in the renal tubules
cells of Japanese monkeys under fasting stress
Tutik Wresdiyatia, b, and Takashi Makitab
a
Department of Anatomy, Faculty of Veterinary Medicine, Bogor Agricultural University, Jl. Taman Kencana 3, Bogor 16151, Indonesia
b
Department of Veterinary Anatomy, Faculty of Agriculture, Yamaguchi University, 1677-1 Yoshida, Yamaguchi shi 753, Japan
Received 10 April 1995; accepted 18 April 1995. ; Available online 19 January 2000.
Abstract
As an extention of work on peroxisome proliferation in the kidney, fine structural alteration of epithelial cells of renal tubules of male and female Japanese monkeys under fasting stress was examined. A total of 6 monkeys (male 3, female 3) for control groups and 9 monkeys (male 4, female 5) for fasting groups were used for this experiment. Both the number and area of peroxisomes per unit cytoplasmic area (number/μm2and μm2/μm2) in the epithelial cells of renal tubules significantly increased in fasting groups. It was more evident in the males than in females. The activity of catalase was localized on the matrix of peroxisomes. In fasting groups peroxisomes had two or more marginal plates. Proliferated peroxisomes were hexagonal or polygonal in shape. Microperoxisomes, which are not significant in the control groups, also increased under fasting stress.
