sear vpdupdate week48 2017

(1)

Immunization and Vaccine

Development (IVD) SEARO

Protecting People from Vaccine

Preventable Diseases

VPD Update for Week 48, 2017

(2)

Last wild poliovirus cases confirmed by type, SEAR

WPV Type 2 District: Aligarh

State: Uttar Pradesh (India) Date of onset: 24-Oct-1999

WPV Type 3 District: Pakur State: Jharkhand (India) Date of onset: 22-Oct-2010

WPV Type 1 District: Howrah

State: West Bengal (India) Date of onset: 13-Jan-2011

Country

Year

Bangladesh

2006

Bhutan

1986

DPR Korea

1996

India

2011

Indonesia

2006

Maldives

1994

Myanmar

2007

Nepal

2010

Sri Lanka

1993

Thailand

1997

Timor-Leste

1995

Last wild poliovirus

(3)

Monthly Distribution of AFP Cases

SEAR, 2016

–

2017

Bangladesh

1 437

1 301

100

99

65

114

119

135

147

125

96

153

108

111

132

61

04-Dec-17

Bhutan

11

8

0

2

1

0

1

2

0

1

0

3

1

0

02-Dec-17

DPR Korea

105

79

5

4

0

14

10

8

13

7

13

3

11

0

29-Sep-17

India

46 500 34 984 3 675 3 364 3 230 3 152 2 749 2 870 2 751 3 056 3 160 3 998 4 777 3 747 3 050 1 674 01-Dec-17

Indonesia

1 409

1 236

0

102

110

113

105

113

76

111

137

139

165

65

04-Dec-17

Maldives

2

5

0

1

2

0

1

0

1

27-Nov-17

Myanmar

466

322

54

33

29

18

24

14

18

24

28

52

64

39

30

11

01-Dec-17

Nepal

455

314

37

19

20

34

27

34

31

33

22

34

43

21

26

9

04-Dec-17

Sri Lanka

65

7

3

6

7

13

6

4

6

4

1

6

3

11

4

01-Dec-17

Thailand

246

166

24

20

16

29

20

16

6

10

15

20

28

13

8

1

27-Nov-17

Timor-Leste

10

3

4

1

0

1

0

1

0

1

0

04-Dec-17

TOTAL

50 706 38 483 3 906 3 545 3 367 3 470 3 072 3 198 3 079 3 375 3 414 4 374 5 175 4 076 3 424 1 826

AFP cases by month of paralysis onset, last 14 months (data from weekly case-based reports)

Country

2016

total

AFP

2017

AFP to

date

A

p

r-1

7

M

a

y

-1

7

Ju

n

-1

7

Date of last

report

O

c

t-1

6

N

o

v

-1

6

D

e

c

-1

6

Ja

n

-1

7

F

e

b

-1

7

M

a

r-1

7

Ju

l-1

7

S

e

p

-1

7

A

u

g

-1

7

N

o

v

-1

7

O

c

t-1

7

(4)

Primary Culture Results from AFP Cases, 2016

<14 days >14 days

V a c c ine V D P V W il d

Bangladesh IPH, Dhaka 1 433 8 0 348 1 077 0 0 2 863 98.4 21.3 64 2 0 0 Bhutan NIH, Bangkok 10 1 0 0 9 0 0 20 100 0 0 0 0 0 DPRK NPL, Pyongyang 91 0 0 14 77 0 0 194 93 14.4 0 0 0 0 BJMC, Ahmedabad 6 098 233 26 1 127 4 712 0 0 12 173 99.9 14.8 20 2 0 0 NIV, Bengaluru 4 395 190 35 1 200 2 970 0 0 8 791 97.4 22.9 0 0 0 0 IoS, Kolkatta 7 146 91 21 1 011 6 023 0 0 14 287 98.4 11.0 5 0 0 0 KIPM, Chennai 5 122 89 9 954 4 070 0 0 10 232 99.8 14.9 0 0 0 0 NCDC, Delhi 6 934 212 20 885 5 817 0 0 13 830 99.6 10.8 10 0 0 0 CRI, Kasauli 2 066 35 0 276 1 755 0 0 4 142 99.9 11.5 0 0 0 0 SGPGI, Lucknow 8 811 281 29 1 551 6 950 0 0 17 602 89.7 13.5 0 0 0 0 ERC, Mumbai 4 940 158 14 1 187 3 581 0 0 9 974 97.4 21.0 45 4 0 0

India Sub Total 45 512 1 289 154 8 191 35 878 0 0 91 031 97.1 14.7 80 6 0 0

Bio Farma, Bandung 440 13 0 40 387 0 0 871 95 7.9 0 0 0 0 NIHRD, Jakarta 513 14 2 45 452 0 0 1 016 98 7.3 0 0 0 0 PHL, Surabaya 402 14 0 27 361 0 0 799 100 5.4 0 0 0 0

Indonesia Sub Total 1 355 41 2 112 1 200 0 0 2 686 97.5 6.9 0 0 0 0

Maldives MRI, Colombo 2 0 0 0 2 0 0 4 100 0 0 0 0 0 Myanmar NHL, Yangon 466 5 2 63 396 0 0 931 96 11.7 0 0 0 0 NIH, Bangkok 449 4 2 103 340 0 0 898 100 20.1 67 3 0 0 Labs in India3 ₃ ₀ ₀ ₀ ₃ ₀ ₀ ₆ ₀ _0.0 ₀ ₀ ₀ ₀ Sri Lanka MRI, Colombo 53 1 0 3 49 0 0 104 81 3.8 266 6 0 0 Thailand NIH, Bangkok 235 4 0 25 206 0 0 468 100.0 8.3 0 0 0 0 Timor-Leste NIH, Bangkok 0

49 609 1 353 160 8 859 39 237 0 0 99 205 97.2 14.6 477 17 0 0

1_{Calculation based on date specimen received in laboratory subtracted from date result report to the national programme.}

2_{Stool samples collected from contact and healthy children survey.}3_{Stool samples from cross notified AFP cases tested in India}

Nepal

SEAR

Indonesia

Country Polio Laboratories

Number of AFP cases with specimens received

in Lab

AFP cases AFP specimens

%

N

P

E

V

Specimens from other sources2 Positive Culture Positive Culture + NPEV India Received by lab

% Primary Culture Reports Within 14

(5)

Primary Culture Results from AFP Cases, 2017

<14 days >14 days

V a c c ine V D P V W il d

Bangladesh IPH, Dhaka 1 294 17 2 279 919 30 47 2 583 90.0 19.3 84 1 0 0 Bhutan NIH, Bangkok 4 0 0 1 3 0 0 8 100 25 0 0 0 0 DPRK NPL, Pyongyang 75 0 0 14 61 0 0 152 93.2 18.4 0 0 0 0 BJMC, Ahmedabad 4 906 195 27 997 3 543 144 0 9 783 95.5 17.2 10 0 0 0 NIV, Bengaluru 3 154 124 24 842 2 052 111 1 6 297 96.9 23.1 5 0 0 0 IoS, Kolkatta 4 968 156 18 1 153 3 609 32 0 9 863 83.8 18.8 0 0 0 0 KIPM, Chennai 2 888 42 7 580 2 258 1 0 5 675 99.2 16.5 0 0 0 0 NCDC, Delhi 5 295 181 22 773 4 192 127 0 10 563 97.5 12.8 5 0 0 0 CRI, Kasauli 1 735 19 1 265 1 431 19 0 3 476 97.8 12.2 0 0 0 0 SGPGI, Lucknow 8 124 252 35 1 916 5 769 152 0 16 220 90.5 19.0 5 0 0 0 ERC, Mumbai 2 257 129 13 389 1 726 0 0 4 471 92.8 15.3 5 0 0 0

India Sub Total 33 327 1 098 147 6 915 24 580 586 1 66 348 93.3 17.3 30 0 0 0

Bio Farma, Bandung 357 2 0 28 321 2 4 709 90 7.4 0 0 0 0 NIHRD, Jakarta 494 1 0 36 419 23 15 975 100 6.6 0 0 0 0 PHL, Surabaya 324 1 0 32 285 5 1 641 100 8.9 0 0 0 0

Indonesia Sub Total 1 175 4 0 96 1 025 30 20 2 325 97.0 7.5 0 0 0 0

Maldives MRI, Colombo 2 0 0 0 2 0 0 3 100 0 0 0 0 0 Myanmar NHL, Yangon 322 4 1 50 259 8 0 648 93 13.6 30 0 0 0 NIH, Bangkok 313 4 1 71 216 21 0 626 99 21.7 19 0 0 0 Labs in India3 ₀ ₀ ₀ ₀ ₀ ₀ ₀ ₀ ₀ _0.0 ₀ ₀ ₀ ₀ Sri Lanka MRI, Colombo 38 0 0 0 38 0 0 82 96 0.0 244 1 0 0 Thailand NIH, Bangkok 129 4 1 9 108 0 7 260 99.2 6.5 0 0 0 0 Timor-Leste NIH, Bangkok 0

36 679 1 131 152 7 435 27 211 675 75 73 035 93.3 17.0 407 2 0 0

1

Calculation based on date specimen received in laboratory subtracted from date result report to the national programme.

2_{Stool samples collected from contact and healthy children survey.}3_{Stool samples from cross notified AFP cases tested in India}

Country Polio Laboratories

Number of AFP cases with specimens received in Lab

AFP cases AFP specimens

%

N

P

E

V

Specimens from other sources2 Positive Culture Number received by lab Results Positive Culture + NPEV Received by lab

% Primary Culture Reports Within 14

days Negative Pending1 Nepal SEAR NPEV Only India Indonesia

(6)

(7)

Poliovirus Detected in Sewage Samples, India, 2017

(8)

Laboratory Data of Environmental Surveillance 2015-2017,

NPML,IPH Bangladesh, Report: November 08,2017)

Laboratory Data of Environmental Surveillance 2015-2017, NPML,IPH Bangladesh, Report: Nov 08,2017)

Report on Epidemiological Week 44, 2017, NPML-IPH, Bangladesh

Site

City

# Site

1

2 3 4

5

6

7

8

9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 #

Dhaka

Niketon

92

95

96

100

104

108

##

Gazipur

Esthema

99

203

107

111

##

c

##

134

##

Dhaka

Gulshan

s94

98

102

106

110

##

133

##

Dhaka

Bashabo

s93

97

101

105

109

##

135

##

Sites:

Bangladesh

Summary

: : Total site 4

Total sample collected

WPV1

Site 1= Hatirjheel-Niketon,Dhaka

Total sample with result available:

175

VDPV

Site 2= Es thema-Kamarpara,Tongi)

Total sample positive for WPV(with type)

0

SLPV2

SLPV1

Site 3= Was a Sewarage Pit-Guls han,Dhaka

Total sample positive for VDPV

0

SL PV3

Site 4= Bas habo Sewarage pit,Dhaka

Total sample positive for SLPV3

9

NPEV

Sample collected fortnightly

Total sample positive for SLPV2

1

Negetive (NVI)

Total sample positive for SLPV1

3

Discordant

Total sample positive for NPEV

89

under process

Total RD Positive:

102

Total sample NVI:

73

Not collected

processing: 3

Reported by National Polio(AFP-ES) Measles-Rubella and AMES(JE) Laboratory, IPH, Bangladesh

178

Note: NPML-IPH lab processes: Sewage samples are tested in cell culture, virus isolation done, confirmed by realtime PCR (ITD)

(9)

Poliovirus Detected in Sewage Samples

Province 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52

DKI Jakarta East Java West Java Yogyakarta

Province 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53

Bangkok Samut Sakhon

Province 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52

Bangkok Samut Sakhon

Type 1 Sabin Type 1 VDPV Wild polio type 1 Negative for Polio and NPEV Type 2 Sabin Type 2 VDPV Wild polio type 3 Result pending

Type 3 Sabin Type 3 VDPV NPEV Sampling not scheduled Type 1 Sabin + 3 Sabin

Thailand- 2017

Thailand -2016

Indonesia - 2017

(10)

Measles and Rubella Serology (IgM) , 2017

# % # %

Banglade s h Dhaka 5971 5971 2491 41.7 204 5.9 66.0

Bhutan Thimphu 421 421 64 15.2 7 2.0 91.4

DPR Kore a Pyongyang 67 61 0 0.0 0 0.0 100.0

Ahmedabad 444 444 308 69.4 30 22.1 100.0

Bengaluru 716 646 145 22.4 170 33.9 91.5

Bhopal 168 168 120 71.4 4 8.3 99.4

Chandigarh 118 118 38 32.2 11 13.8 100.0

Chennai 893 178 50 28.1 64 50.0 98.3

Delhi 132 132 83 62.9 6 12.2 97.0

Guw ahati 272 153 103 67.3 14 28.0 100.0

Hyderabad 80 80 32 40.0 7 14.6 100.0

Jaipur 313 313 213 68.1 7 7.0 80.2

Kolkata 812 812 318 39.2 302 61.1 86.6

Lucknow 1631 1462 866 59.2 88 14.8 78.0

Patna 399 399 112 28.1 115 40.1 63.2

Pune 653 476 275 57.8 45 22.4 91.0

6631 5381 2663 49.5 863 31.8 86.2

Bandung 1146 1146 580 50.6 173 30.6 93.0

Jakarta 4886 3274 902 27.6 1042 43.9 29.4

Surabaya 3790 2798 1419 50.7 448 32.5 50.4

Yogyakarta 3774 3554 984 27.7 1141 44.4 77.3

13596 10772 3885 36.1 2804 40.7 57.4 Maldive s Male 63 63 1 1.6 1 1.6 88.9

Myanm ar Yangon 1493 1491 988 66.3 6 1.2 99.1

Ne pal Kathmandu 769 769 56 7.3 18 2.5 91.0

Sri Lank a Colombo 138 137 5 3.6 8 6.1 86.1

Bangkok 579 579 303 52.3 3 1.1 100.0

Chiang Mai 34 34 12 35.3 0 0.0 100.0

Chiang Rai 29 29 7 24.1 0 0.0 86.2

Chon Buri 232 151 52 34.4 1 1.0 100.0

Khon Kaen 55 55 11 20.0 1 2.3 100.0

Nakhon Saw an 8 8 3 37.5 0 0.0 100.0

Nakhonratchasima 63 63 27 42.9 3 8.3 100.0

Phitsanulok 55 55 15 27.3 2 5.0 100.0

Samut Songkhram 419 419 257 61.3 5 3.1 98.1

Songkhla 784 784 631 80.5 3 2.0 100.0

Surat Thani 7 7 0 0.0 0 0.0 100.0

Trang 54 54 10 18.5 8 18.2 100.0

Ubon Ratchathani 55 55 9 16.4 1 2.2 100.0

Udon Thani 15 15 5 33.3 0 0.0 100.0

2389 2308 1342 58.1 27 2.8 99.5 Tim or-Le s te Dili 80 80 0 0.0 3 3.8 87.5

India Total

Country Laboratorie s Num be r of Se rum

Sam ple s Re ce ive d Num be r Te s te d Me as le s +ve Rube lla +ve

India

Re s ults

% Me as le s Re s ults Re porte d w ithin 4 Days

Indone s ia Indone s ia Total

Thailand