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A new strategy to stabilize oxytocin in aqueous solutions: i. the effects of divalentt metal ion and citrate buffer.

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Academic year: 2017

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Fig. 1. Recovery of oxytocin in the presence of divalent metal ions inRP-HPLC.The results are depicted as averages of three independentconcentrations of 2, 5, 10, and 50 mM.non-buffered, pure water stored for 4 weeks at pH 4.5 and atemperature of 4°C (ligh
Fig. 2. Recovery of oxytocin in pure water, with or without amonomer recovery determined by HP-SEC
Fig. 4. Oxytocin recovery over time storage at 40°C and pH 4.5 in thesymbolsin concentrations of 10 mM (recovery determined by HP-SEC
Table I. Thermodynamics of Divalent Metal binding to Oxytocin as Determined by Isothermal Titration Calorimetry in 10 mM Citrate Buffer

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A new strategy to stabilize oxytocin in aqueous solutions: i. the effects of divalentt metal ion and citrate buffer.

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