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Immunization and Vaccine

Development (IVD) SEARO

Protecting People from Vaccine

Preventable Diseases

Monthly Vaccine Preventable Disease and

Immunization Update

(2)

Last wild poliovirus case by type, SEAR

*Dots are randomly placed within blocks (Sub-districts) WPV Type 2

District: Aligarh

State: Uttar Pradesh (India) Date of onset: 24-Oct-1999

WPV Type 3 District: Pakur State: Jharkhand (India) Date of onset: 22-Oct-2010

WPV Type 1 District: Howrah

State: West Bengal (India) Date of onset: 13-Jan-2011

Country

Year

Bangladesh

2006

Bhutan

1986

DPR Korea

1996

India

2011

Indonesia

2006

Maldives

1994

Myanmar

2007

Nepal

2010

Sri Lanka

1993

Thailand

1997

Timor-Leste

1995

(3)

% Adequate Stool Specimen Collection

Non-polio AFP Rate

AFP Surveillance Indicators by First Administrative Level*, 2017

Total AFP Cases = 38483 Non-Polio AFP Rate =6.18 Adequate Stool specimen = 86%

Countries reporting AFP cases= 11 (100%)

*Bhutan, Maldives & Timor-Leste by country

* Number of discarded AFP cases per 100,000 children under 15 years of age. (annualized by week 48, 2017) ** Percentage with 2 specimens 24 hours apart and within 14 days of paralysis onset.

Note: Some AFP cases may still be pending final classification.

Non-Polio AFP Rate

< 1

1 – 1.99

>2

No Non-Polio AFP Case

Adequate Stool Specimen Collection

< 60%

60% – 79%

(4)

Non-polio AFP Cases by Month of Onset

SEAR, 2013-2017

0

1000

2000

3000

4000

5000

6000

7000

Jan

Feb

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

N

um

ber

of

N

on

-pol

io

A

FP

c

a

s

e

s

Month

2013

2014

2015

2016

2017

Month 2013 2014 2015 2016 2017

Jan 4560 4451 4106 4166 3414 Feb 4016 3990 3718 3749 3026 Mar 4279 4185 3680 3610 3140 Apr 4305 4018 3497 3472 2997 May 4430 4500 3788 4064 3241 Jun 5035 5149 4124 4175 3232 Jul 5832 5518 4155 5304 4106 Aug 5940 6414 5124 6034 4605 Sep 6034 6122 5421 4943 3450 Oct 5282 5086 4994 4023 2574 Nov 5171 4952 4196 3655 668 Dec 4534 4095 4091 3495

(5)

0

0.5

1

1.5

2

2.5

3

3.5

4

4.5

5

5.5

6

BAN

BHU

DPRK

IND

INO

MAV

MMR

NEP

SRL

THA

TLS

N

o

n

-P

o

li

o

A

F

P

R

a

te

2013

2014

2015

2016

2017

Non-polio AFP Rate*

SEAR, 2013

2017

* Number of discarded AFP cases per 100,000 children under 15 years of age

SEAR Minimum Target

and above

~~~~~~~~

10.77 12.48 12.50

10.60

(6)

Percent Adequate Stool Specimen Collection*

SEAR, 2013-2017

0

20

40

60

80

100

BAN

BHU

DPRK

IND

INO

MAV

MMR

NEP

SRL

THA

TLS

2013

2014

2015

2016

2017

Minimum Target

Per

cent

(7)

0.0 5.0 10.0 15.0 20.0 25.0 30.0 35.0

2013 2014 2015 2016 2017 2013 2014 2015 2016 2017 2013 2014 2015 2016 2017 2013 2014 2015 2016 2017 2013 2014 2015 2016 2017 2013 2014 2015 2016 2017

Bangladesh India Indonesia Myanmar Nepal Thailand

P

er

cent

Zero OPV Dose <3 OPV Doses (Under Immunized) Unknown OPV Doses

N= 79 4 N= 83 8 N= 30 57 1 N= 96 4 N= 14 5 N= 29 1 N= 76 N= 79 0 N= 23 61 2 N= 75 1 N= 17 3 N= 20 9 N= 10 0

Percent of Non-Polio AFP Cases Under Immunized for OPV

(6 Months to 5 Yrs), SEAR, 2013-2017

(8)

Total AFP Cases = 34984 Non-Polio AFP Rate =7.75 Adequate Stool specimen = 86%

Districts reporting AFP cases= 686(97%)

* Number of discarded AFP cases per 100,000 children under 15 years of age (annualized by week 48, 2017) ** Percentage with 2 specimens 24 hours apart and within 14 days of paralysis onset.

Note: Some AFP cases may still be pending final classification.

Adequate Stool Specimen Collection

< 60%

60% – 79%

> 80% No AFP Case

Non-Polio AFP Rate

< 1

1 – 1.99

>2

No Non-Polio AFP Case

AFP Surveillance Indicators by District

India, 2017

Non-polio AFP Rate*

Percent Adequate Stool

(9)

Non-polio AFP Cases by Month of Onset

India, 2013-2017

0

1000

2000

3000

4000

5000

6000

7000

Jan

Feb

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

N

um

ber

of

N

on

-pol

io

A

FP

c

a

s

e

s

Month

Month 2013 2014 2015 2016 2017

Jan 4132 4110 3774 3838 3111 Feb 3644 3657 3442 3440 2714 Mar 3885 3781 3329 3214 2821 Apr 3864 3621 3207 3124 2683 May 4007 4042 3430 3691 2941 Jun 4622 4683 3763 3787 3007 Jul 5385 5168 3888 4911 3758 Aug 5555 6035 4765 5635 4254 Sep 5590 5747 5082 4579 3153 Oct 4888 4711 4612 3675 2287 Nov 4777 4565 3866 3361 651 Dec 4245 3790 3799 3229

(10)

AFP Surveillance Indicators by District

Nepal, 2017

Total AFP Cases = 314 Non-Polio AFP Rate =3.63 Adequate Stool specimen = 98% Districts reporting AFP cases= 66 (88%)

* Number of discarded AFP cases per 100,000 children under 15 years of age. (annualized by week 48, 2017) ** Percentage with 2 specimens 24 hours apart and within 14 days of paralysis onset.

Note: Some AFP cases may still be pending final classification.

Non-polio AFP Rate*

Percent Adequate Stool

Specimen Collection **

Adequate Stool Specimen Collection

< 60%

60% – 79%

> 80% No AFP Case

Non-Polio AFP Rate

< 1

1 – 1.99

>2

(11)

Non-polio AFP Cases by Month of Onset

Nepal, 2013-2017

0

10

20

30

40

50

60

70

Jan

Feb

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

N

umb

er

of Non

-poli

o

A

FP ca

se

s

Month

Month 2013 2014 2015 2016 2017

Jan 32 50 32 31 34

Feb 41 48 32 23 27

Mar 61 40 46 38 34

Apr 56 31 25 42 31

May 49 41 20 44 32

Jun 57 42 38 58 22

Jul 65 47 38 57 33

Aug 63 38 39 38 42

Sep 47 40 36 48 21

Oct 30 37 29 37 15

Nov 37 38 24 19

Dec 38 34 35 20

(12)

AFP Surveillance Indicators by Province

Myanmar, 2017

Total AFP Cases = 322 Non-Polio AFP Rate = 2.49 Adequate Stool specimen = 97%

Provinces reporting AFP cases= 18 (100%)

Non-polio AFP Rate*

Percent Adequate Stool

Specimen Collection **

Adequate Stool Specimen Collection

< 60%

60% – 79%

> 80% No AFP Case

Non-Polio AFP Rate

< 1

1 – 1.99

>2

No Non-Polio AFP Case

* Number of discarded AFP cases per 100,000 children under 15 years of age (annualized by week 48, 2017) ** Percentage with 2 specimens 24 hours apart and within 14 days of paralysis onset.

(13)

0

10

20

30

40

50

60

70

80

90

Jan

Feb

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

Num

be

r

of

Non

-po

li

o

A

FP

c

a

s

e

s

Month

2013

2014

2015

2016

2017

Non-polio AFP Cases by Month of Onset

Myanmar, 2013-2017

Month 2013 2014 2015 2016 2017

Jan 32 41 22 29 18

Feb 13 24 21 27 24

Mar 16 19 17 17 14

Apr 20 22 14 18 18

May 18 38 27 23 24

Jun 27 38 19 50 28

Jul 34 39 26 79 52

Aug 36 47 33 56 64

Sep 27 42 35 51 37

Oct 49 29 42 54 28

Nov 63 24 25 33 3

Dec 69 26 52 29

(14)

AFP Surveillance Indicators by District

Bangladesh, 2017

Total AFP Cases = 1301 Non-Polio AFP Rate =2.63

Non-polio AFP Rate*

Percent Adequate Stool Specimen

Collection **

Adequate Stool Specimen Collection

< 60%

60% – 79%

> 80% No AFP Case

Non-Polio AFP Rate

< 1

1 – 1.99

>2

No Non-Polio AFP Case

* Number of discarded AFP cases per 100,000 children under 15 years of age (annualized by week 48, 2017) ** Percentage with 2 specimens 24 hours apart and within 14 days of paralysis onset.

(15)

Non-polio AFP Cases by Month of Onset

Bangladesh, 2013-2017

0

50

100

150

200

250

Jan

Feb

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

N

um

ber

of

N

on

-pol

io

A

FP

c

a

s

e

s

Month

Month 2013 2014 2015 2016 2017

Jan 155 73 87 126 111 Feb 110 69 100 118 117 Mar 107 115 127 139 135 Apr 125 130 121 136 147 May 148 169 171 143 123 Jun 149 198 134 121 95 Jul 134 154 110 146 151 Aug 116 168 139 122 104 Sep 125 117 101 122 111 Oct 95 102 137 100 115 Nov 94 104 115 99

Dec 54 79 71 65

(16)

AFP Surveillance Indicators by Province

Indonesia, 2017

Total AFP Cases = 1236 Non-Polio AFP Rate = 1.58 Adequate Stool specimen = 84%

Provinces reporting AFP cases= 32 (94%)

Non-polio AFP Rate*

* Number of discarded AFP cases per 100,000 children under 15 years of age. (annualized by week 48, 2017)

Percent Adequate Stool Specimen Collection **

Adequate Stool Specimen Collection

< 60%

60% – 79%

> 80% No AFP Case

Non-Polio AFP Rate

< 1

1 – 1.99

>2

(17)

Non-polio AFP Cases by Month of Onset

Indonesia, 2013-2017

0

50

100

150

200

250

Jan

Feb

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

N

um

ber

of

N

on

-pol

io

A

FP

c

a

s

e

s

Month

Month 2013 2014 2015 2016 2017

Jan 169 135 153 101 91

Feb 181 149 110 101 104

Mar 174 198 123 163 108

Apr 195 184 107 135 95

May 163 172 110 130 102

Jun 144 155 129 109 64

Jul 166 66 53 75 93

Aug 131 87 115 134 113

Sep 205 158 133 102 120

Oct 182 165 150 117 122

Nov 158 170 136 113 11

Dec 94 125 109 129

(18)

AFP Surveillance Indicators by Province

Thailand, 2017

Total AFP Cases = 166 Non-Polio AFP Rate = 1.22 Adequate Stool specimen = 66%

Provinces reporting AFP cases= 64 (83%)

Annualized Non-polio AFP Rate*

* Number of discarded AFP cases per 100,000 children under 15 years of age. (annualized by week 48, 2017)

Percent Adequate Stool Specimen Collection **

Adequate Stool Specimen Collection

< 60%

60% – 79%

> 80% No AFP Case

Non-Polio AFP Rate

< 1

1 – 1.99

>2

(19)

Non-polio AFP Cases by Month of Onset

Thailand, 2013-2017

Month 2013 2014Jan 19 24 201515 2016 201725 28

Feb 20 25 5 25 17

Mar 24 12 12 21 13

Apr 22 16 16 5 4

May 19 17 17 16 10

Jun 17 18 18 24 12

Jul 27 27 18 16 18

Aug 19 18 14 24 22

Sep 18 11 19 30 6

Oct 16 19 11 24 0

Nov 18 25 21 20

Dec 16 26 17 16

Total 235 238 183 246 130

0

5

10

15

20

25

30

35

Jan

Feb

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

Nu

m

b

e

r

o

f

No

n

-p

o

li

o

A

F

P

c

a

s

e

s

(20)

VPD Reporting, 2017

# O u tb re a ks # C a se s # O u tb re a ks # C a se s # O u tb re a ks # C a se s

Bangladesh 5463 15 5039 2157 183 158 158 2118 9 70 1265 4 60 11 257 79 3 0 0 2081 29-Nov-17 10 100 90

Bhutan 420 0 420 64 31 4 0 0 0 0 0 0 0 0 0 0 0 0 0 9 09-Nov-17 10 90 80

DPR Korea 67 0 61 0 0 67 67 67 0 0 0 0 0 0 0 0 0 0 0 0 29-Sep-17 10 80 40

India 38612 79 NR NR NR 1430 824 13804 52 436 7604 115 2268 15 226 536 85 90 0 6 29-Nov-17 10 70 0

Indonesia 6979 2 4924 452 146 122 107 1447 0 32 161 8 47 2 9 20 374 11 0 0 15-Nov-17 10 100 80

Maldives 58 0 58 1 0 1 1 1 0 1 1 0 0 0 0 0 0 0 0 10 11-Oct-17 10 80 50

Myanmar 1186 0 1186 802 3 19 19 440 0 15 446 0 0 0 0 14 48 4 0 0 17-Nov-17 10 90 70

Nepal 610 3 582 28 14 8 8 132 4 4 54 0 0 0 0 2 NR NR 791 11 15-Nov-17 10 100 90

Sri Lanka 215 0 195 4 10 0 0 0 0 0 0 0 0 0 0 0 0 13 155 8969 15-Nov-17 10 100 70

Thailand 2308 0 1966 1164 21 15 15 179 0 11 160 0 0 0 0 0 4 52 697 NR 15-Nov-17 10 80 30

Timor-Leste 120 0 95 0 2 0 0 0 0 0 0 0 0 0 0 1 0 1 1 2 20-Nov-17 10 50 20

Total 56038 99 14526 4672 410 1824 1199 18188 65 569 9691 127 2375 28 492 652 514 171 1644 11088

1

At least 5 blood samples should be collected and tested from each outbreak. 2

Adverse Events Follow ing Immunization; Sri Lanka AEFI data do not reflect cases but events.

3

Monthly VPD and AEFI reports due to SEARO/IVD on or before 15th of each month. NR=No report

Rubella Outbreaks Mixed Outbreaks N e o n a ta l Te ta n u s D ip h th e ri a P e rt u s s is E n c e p h a li ti s D a te of l a s t re po rt # r e po rt s e x pe c te d % C om pl e te ne s s % Ti m e li ne s s

Number of Cases

N um be r of C a s e s of A E FI 2 # O u tb re a ks Country

Routine Reporting of clinically suspected measles cases

Suspected measles

outbreaks Laboratory Confirmed

(21)

Measles and Rubella Serology (IgM), 2017

# % # %

Banglade s h Dhaka 5971 5971 2491 41.7 204 5.9 66.0

Bhutan Thimphu 421 421 64 15.2 7 2.0 91.4

DPR Kore a Pyongyang 67 61 0 0.0 0 0.0 100.0

Ahmedabad 444 444 308 69.4 30 22.1 100.0

Bengaluru 716 646 145 22.4 170 33.9 91.5

Bhopal 168 168 120 71.4 4 8.3 99.4

Chandigarh 118 118 38 32.2 11 13.8 100.0

Chennai 893 178 50 28.1 64 50.0 98.3

Delhi 132 132 83 62.9 6 12.2 97.0

Guw ahati 272 153 103 67.3 14 28.0 100.0

Hyderabad 80 80 32 40.0 7 14.6 100.0

Jaipur 313 313 213 68.1 7 7.0 80.2

Kolkata 812 812 318 39.2 302 61.1 86.6

Lucknow 1631 1462 866 59.2 88 14.8 78.0

Patna 399 399 112 28.1 115 40.1 63.2

Pune 653 476 275 57.8 45 22.4 91.0

6631 5381 2663 49.5 863 31.8 86.2

Bandung 1146 1146 580 50.6 173 30.6 93.0

Jakarta 4886 3274 902 27.6 1042 43.9 29.4

Surabaya 3790 2798 1419 50.7 448 32.5 50.4

Yogyakarta 3774 3554 984 27.7 1141 44.4 77.3

13596 10772 3885 36.1 2804 40.7 57.4

Maldive s Male 63 63 1 1.6 1 1.6 88.9

Myanm ar Yangon 1493 1491 988 66.3 6 1.2 99.1

Ne pal Kathmandu 769 769 56 7.3 18 2.5 91.0

Sri Lank a Colombo 138 137 5 3.6 8 6.1 86.1

Bangkok 579 579 303 52.3 3 1.1 100.0

Chiang Mai 34 34 12 35.3 0 0.0 100.0

Chiang Rai 29 29 7 24.1 0 0.0 86.2

Chon Buri 232 151 52 34.4 1 1.0 100.0

Khon Kaen 55 55 11 20.0 1 2.3 100.0

Nakhon Saw an 8 8 3 37.5 0 0.0 100.0

Nakhonratchasima 63 63 27 42.9 3 8.3 100.0

Phitsanulok 55 55 15 27.3 2 5.0 100.0

Samut Songkhram 419 419 257 61.3 5 3.1 98.1

Songkhla 784 784 631 80.5 3 2.0 100.0

Surat Thani 7 7 0 0.0 0 0.0 100.0

Trang 54 54 10 18.5 8 18.2 100.0

Ubon Ratchathani 55 55 9 16.4 1 2.2 100.0

Udon Thani 15 15 5 33.3 0 0.0 100.0

2389 2308 1342 58.1 27 2.8 99.5

Tim or-Le s te Dili 80 80 0 0.0 3 3.8 87.5

31618 27454 11495 41.9 3941 24.7 72.6

India Total

Country Laboratorie s Num be r of Se rum

Sam ple s Re ce ive d Num be r Te s te d Me as le s +ve Rube lla +ve

India

Re s ults

% Me as le s Re s ults Re porte d w ithin 4 Days

Indone s ia

Indone s ia Total

Thailand

Thailand Total

Referensi

Garis besar

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