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Evaluasi Efek Fraksi N-Heksan, Etil Asetat dan Etanol Daun Puguntano (Picria felterrae Lour.) Terhadap Sistem Kardiovaskuler Tikus

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Abdulazeez, M.A. Ibrahim, S. Ameh, D.A. Ayo, J.O. Carvalho, L.J.C.B. Manosroi, J.J. Ibrahim, A.B. (2015). Bioassay$Guided Fractionation And Antihypertensive Properties Of Fractions And Crude Extracts Of

(Retz) Nees. 72 (2) : 319$328

Alamgeer, Ahmad, T. Malik, M.N.H. Mushtaq, M.N. Khan, J. Qayyum, R. Khan, A. Q. Akhtar, S. Ghuffar, A. (2015). Evaluation of Antihypertensive Effect of Aqueous Methanol Extract of Caralluma tuberculata N.E.Br in

Sprauge Dawley Rats. 14

(3): 455$462

Anonim. (2009). . Diunduh tanggal 3 Maret 2011 http:// www.proseanet.org/prohati$4/printer.php?photoid=459

Anonim. (2011). Curanga fel$terrae (Lour.) Merr. Diunduh tanggal 3 Maret 2011 http://www.bpi.da.gov.ph/Publications/mp/pdf/s/sagai$usak.pdf.

Asif, M. Jabeen, Q. Atif, M. Majid, A.M.S.A. Qamar$uz$Zaman, M. (2014). Diuretic Activity of Achyranthes aspera Linn Crude Aqueous Extract in

Albino Rats. 13 (12): 2039$

2045

Babu, P.R. Peter, H.P.L. Ankaiah, M. Sairam, P.H. Ramesh, M. (2012). Positive Inotropic Actvity Of Aqueous Extract Of Pericarp Of Punica Granatum On Isolated Frog’s Heart.

4(3): 95$98

Berkban, T. Boonprom, P. Bunbupha, S. Welbat, J.U. Kukongviriyapan, U. Kukongviriyapan, V. Pakdeechote, P. Prachaney, P. (2015). Ellagic Acid Prevents L$NAME$Induced Hypertension via Restoration of eNOS and p47phox Expression in Rats. 7: 5265$5280

Chandra, K. R. Y. Sandya, L. Sandeep, D. Ruth, S. K. Nagarjuna, S.Padmanabha, R. Y. (2011). Evaluation of diuretic activity of aqueous and ethanolic extracts of leaves in rats.

1 (3):28$33

Corti, R. Flammer, A.J. Hollenberg, N.K. (2009). Cocoa and Cardiovascular.

! : 1433$1441

(2)

Dalimunthe, A. Harahap, U. Rosidah. Nasution, M. P. (2015). Evaluation of Diuretic Activity of Picria fel$terrae Lour Leaves Extract.

! 8(4): 204$205

Delima. Mihardja, L. Siswoyo, H. (2009). Prevalensi dan Faktor Determinan Penyakit Jantung Di Indonesia. Buletin Peneltian Kesehatan 37(3): 142$ 159

Deng, G.M. and Xu, J. (1992). Poriatin: a potential aldosterone antagonist. ! " " # 17 : 34–37

Departemen Kesehatan RI. (1979). Farmakope Indonesia. Edisi Ketiga. Jakarta: Depkes. Hal. 29$31, 33, 649, 748

Departemen Kesehatan RI. (1995). Farmakope Indonesia. Edisi Keempat. Jakarta: Depkes. Hal. 29$31, 33, 649, 748

Dipiro, J.T., Talbert, R.L., Yee, G.C., Matzke, G.R., Wells, B.G., Posey, M.L. (2008). Pharmacotherapy – A Phatophysiologic Approach. Seventh Edition. McGraw$Hill Companies. USA. Page: 173$216

Ditjen POM. (1986). Materia Medika Indonesia. Jilid VI. Jakarta: Departemen Kesehatan RI. Hal. 300$ 306, 321, 325, 333$337.

Ditjen POM. (1995). Materia Medika Indonesia. Jilid VI. Jakarta: Departemen Kesehatan RI. Hal. 300$ 306, 321, 325, 333$337.

Ditjen POM. (2000). Parameter Standar Umum Ekstrak Tumbuhan Obat. Cetakan Pertama. Jakarta: Departemen Kesehatan RI. Hal. 10$11.

Echegoyen, C.G. Pacheco, R.P. Aguilera, A.A. Rivera, L.L. Hernandez, N.A. Martinez, E.C. (2015). Effects of aqueous and ethanol extract of dried leaves of Pseudocalymma alliaceum (Bignonaceae) on haematological and biochemical parameters of wistar rats.

4(2): 129$134

Feng, Y.L. Lei, P. Tian, T. Yin, L. Chen, D.Q. Chen, H. Mei, Q. Zhao, Y.Y. Lin, R.C. (2013). Diuretic Activity of Some Fractions of The Epidermis of

" $ 150(3) :1114$1118

Furqon, M. Hadisahputra, S. Rosidah. (2014). Effects of Inhibition Cell Cycle and Apoptosis of Puguntano Leaves Ethylacetate Extract (Picria fel$terrae Lour.) on Breast Cancer Cell.

6(3) : 1096$1099

Gilani, A.H. Jabeen, Q. Khan, A.U. Shah, A.J. (2008). Gut Modulatory, Blood Pressure Lowering, Diuretic and Sedative Activities of Cardamom.

(3)

Globinmed. (2007). . Diunduh pada tanggal 5 Mei 2010 From: http://www.globinmed.com/IMRContent/ detail.aspx?id=BOT00054.

Gogebakan, A. Talas, Z.S. Ozdemir, I. Sahna, E. (2012). Role of Propolis on Tyrosine hydroxylase Activity and Blood Pressure in Nitric Oxide Synthase$inhibited Hypertensive Rats. ! " $% " & ., 34(6): 424$ 428.

Harahap, U. Patilaya, P. Marianne. Yuliasmi, S. Husori, D.I. Prasetyo, B.E. Laila, L. Sumantri, I.B. Wahyuni, H.S. (2013). Profil Fitokimia Ekstrak Etanol Daun Puguntano (Curanga fel$terrae (Merr) Lour) Yang Berpotensi Sebagai Antiasma. Seminar Nasional Sains dan Teknologi V. Lembaga Penelitian Universitas Lampung. Page 422$426

Harbone, J.B. (1987). ' ( ) * ! ' '

# * terjemahan K.Padmawinata. Edisi II. Bandung : ITB Press. Hal. 6, 71 ,76 ,84$85, 94$97

Harwoko. Pramono, S. Nugroho, A. E. (2014).Triterpenoid$rich fraction of

! leaves and + + antihypertensive activity.

( 21(1): 149$154

He, X. Zhang, Y. Gao, H. Li, K. Zhang, Y. Su, L. Tao, G. (2016). Simultaneuos Quantification of Picfeltarraenins 1A & 1B in Rats Plasma by UPLP.MS/MS: Application to a Pharmacokinetic Study.

120: 32$37

Huang, Y. Bruyne, T.D. Apers, S. Ma, Y. Claeys, M. Berghe, D.V. Pieters, L. Vlietinck, A. (1998). Complement$Inhibiting Cucurbitacin Glycosides from " " " " 61 (6): 757–761

Huang, Y. Bruyne, T.D. Apers, S. Ma, Y. Claeys, M. Pieters, L. Vlietinck, A. (1999). Flavonoid glucuronides from Picriafel$terrae.

52(8): 1701–1703

Huang, Y.L. Chen, Y.Y. Wen, Y.X. Li, D.P. Chen, W.J. Liu, J.L. Lu, F.L. (2010). Chemical constituents of Picria fel$terrae Lour. , ! : 887$890

Ikewuchi, J.C. Ikewuchi, C.C. Ifeanacho, M.O. Igboh, N.M. Ijeh, I.I. (2013). Moderation of Hematological and Plasma Indices of Sub$chronic Salt$ Loaded Rats by Aqueous Extract of The Sclerotia of Pleurotus tuberregium (Fr) Sing’s: Implication for The Reduction of Cardiovascular Risk. Journal of Ethnopharmacology 150:466$476

Janardan, N. Ahirwan, D. Singh,M.P. Tiwari,P. (2011). Cardiotonic Activity of Pethrolium Ether and Alcoholic Extract of Seed of Cassia Tora Linn.

(4)

Jijith, U.S. Nair, C.R.S. Pramod, K. (2016). Unveiling The Effect of a Stem Bark Extract on Cardiovascular System.

3(5): 406$409

Junior, A.G. Prando, T.B.L. Leme, T.D.S.V. Gasparotto, F.M. Lourenco, E.L.B. Rattmann, Y.D. Silva$Santos, J.E.D. Kassuya, C.A.L. Marques, M.C.A. (2012). Mechanism Underlying The Diuretic Effects of Tropaeolum majus L. Extract and Its Main Component Isoquercitrin.

$ 141: 501$509

Khan, M.G. (2007). Cardiac Drug Therapy. Seventh Edition. Humala Press, Totowa, New Jersey. Page 1$153

Kukongviriyapan, U. Kukongviriyapan, V. Donpunha, P.P.W. Sripui, J. Sae$Eaw, A. Boonla, O. (2015). Mamao Pomace Extract Alleviates Hypertension and Oxidative Stress in Nitric Oxide Deficient Rats. 7: 6179$ 6194

Lindhlom, L.H. ( 2003). The problem of uncontrolled hypertension. . 16:53$58.

Loizzo, M.R. Said, A. Tundis, R. Rashed, K. Statti, G.A. Hufner, A.(2007). Inhibition of Angiotensin Converting Enzyme (ACE) by Flavonoids Isolated from Ailanthus excelsa (Roxb)(Simaroubaceae).

21(1) :32$36

Malero, P., Medarde, M., dan San, F.A. (2000). A Short Review on Cardiotonik Steroids and Their Aminoguanidine Analoues. ' "5: 51$81.

Malkoff, J. (2005). Non$Invasive Blood Pressure for Mice and Rats. # " 29: 84$90.

Maruyama H, Sumitou Y, Sakamoto T, Araki Y and Hara H (2009). Antihypertensive Effects of Flavonoids Isolated from Brazilian Green Propolis in Spontaneously Hypertensive Rats. " " ., 32(7): 1244$1250.

Mehana, A.S. (2008). ! - ! , * *

" Editor: Thomas L. Limke., David A. Williams., Victoria F. Roche., S. William Zito. ( . '

! % $ . Philadelpia: Lippincott Williams & Wilkins. Hal. 700$703.

(5)

Oztasan, N. Bulbul, A. Eryavuz, A. Avci, G. Kucukkurt, I. Fidan, A. F.( 2008). Effect of / Extract on Blood Pressure, Antioxidant Activity and Some Blood Parameters in the L$name$induced Hypertensive Rats. ) 0 + 1 ( ) 55: 149$153

Pantoja, C.V. Chiang, I.C.H.Norris, B.C. Concha, J.B. (1991). Diuretic, natriuretic and hypotensive effects produced by + (garlic) in anaesthetized dogs. $ 31: 325–331

Patilaya, P. And Husori, D.I. (2015). Preliminary study on the anthelmintic activity of the leaf ethanolic extract of Indonesian Curanga fel$terrae

(Lour.) Merr ). 2 8(3) : 347$

351

Prytzyk, E. Dantas, A.P. Salomão, K. Pereira, A.S. Bankova, V.S. De Castro, S.L.Aquino Neto, F.R. (2003). Flavonoids and trypanocidal activity of Bulgarian propolis. " $ ., 88: 189$193.

Ravikant, T. Nishan, G. Shashipal, S. Samriti, T. Rajeev, T. Kumar. Vikas, V. Dishant, S. (2012). Antihypertensive effect of Ethanolic Extract of Indian Carica papaya l. Root bark (Caricaceae) in Renal Artery Occluded

Hypertensive Rats. !

4(3): 20$23

Ravishankar, K. And Priya, P.S.V.V. (2012). Evaluation Of Diuretic Effect Of Ethanolic Seed Extracts Of ' 3 And ! ' In Rats. 3(3): 251$ 255

Ryu, S.Y. Oh, K.S. Kim, Y.S. Lee, B.H. (2008). Antihypertensive, Vasorelaxant and Inotropic Effects of An Ethanolic Extract of The Roots of

. " $ ., 118: 284$289.

Saboo, S.S. Thorat, P.K. Tapadiya, G.G. Khadabadi, S.S. (2013). Ancient and Recent Medicinal Uses of Cucurbitaceae Family.

9: 11$19

Shouk, R. Abdou, A. Shetty, K. Sarkar, D. Eid, A.H. (2014). Mechanisms Underlying The Antihypertensive Effect of Garlic Bioactives.

34: 106$115

Siska., Armenia., dan Arifin, H. (2011). Akar Seledri ( + L") Sebagai Obat Antihipertensi: Efektivitas Fraksi Etanol Air dan Etil Asetat pada Tikus Putih Jantan Hipertensi. . 6(7): 337$341.

(6)

Shapiro, S,D., dan Loiacono, A.L. (2010). Mean Arterial Pressure: Therapeutic Goals and Pharmacologic Support. ! ! ! . 26: 285–293.

Shi, R. Wang, Q. Ouyang, Y. Wang, Q. Xiong, X. (2016). Picfeltarraenin IA Inhibits Lipopolysaccharide$induced Inflammatory Cytokine Production by The Nuclear Factor$kB Pathway in Human Pulmonary Epithelial A549 Cells. 2 11 : 1195$1200

Sitorus, P. Harahap, U. Nasution, M. P. Barus, T. (2014). Isolation of β$sitosterol from n$Hexane Extract of Picria fel$terrae Lour. Leave and Study of Its Antidiabetic Effect in Alloxan Induced Diabetic Mice Int.J.PharmTech Res. 6(1): 137$141.

Talas, Z.S. Gogebakan, A. Orun, I. (2013). Effects of Propolis on Blood Biochemical and Hematological Parameters in Nitric Oxide Synthase Inhibited Rats By Nw$Nitro$L$Arginin Methyl Ester. )" " " "

26 (5) : 915$919

Thapa, B.R., dan Walia, A. (2007). Liver Function Tests and Their Interpretation. .74(7): 665$667.

Thuan, N.D., Ha, D.T., Thuong, M.K.N., Lee, J.P., Lee, J.H., Seo, H.W., Min, B.S., Kim, J.C., Bae, K.H. (2007). A Phenylpropanoid Glycoside with Antioxidant Activity from Picria tel$ferae. +

30 (9) : 1062$1066

Tthambi, P. Chackot, S.M. Chungath, J.I. (2013). Studies on Diuretic Effect of Linn. Leaf Extracts in Normal Rats.

* ! 4(3): 61$69

Underwood, J.C.E. (1994). ! & ) # 2# . Editor: Sarjadi. Edisi Patologi Umum dan Sistemik Volume 2. Edisi II.Jakarta: ECG. Halaman 483

Verma, P. Muneesh, R.S. Bhutani, G. (2013). Experimental Evaluation of Terminalis Arjuna (Aqueous Extract) on Cardiovascular System in

Comparison to Digoxin. 2 '

7(2): 48$51

Wansi, S.L. Kayem, F.S.F. Nyadjeu, P.Kamanyi, A. (2009). Antioxidative And Antihypertesive Effects Of The Aqueous Leaf Of , # On Rats Fed With High Sodium Chloride Diet. 2 : 750$ 762

(7)

Eells, B.G. Dipiro, J.T. Schwinghammer, T.L. Dipiro, C.V. (2009). Pharmacotherapy Handbook. Seventh Edition. The McGraw$Hill Companies USA. Pages 111$129

Wen, L. Wei, Q. Chen, G. Liu, F. Zhang, S. You, T. (2013). Bioassay$ and Liquid Chromatography / Mass Spectrometry $ guided Acetylcholinesterase Inhibitors from Picriafel$terrae. ' " 9(36): S25–S31.

Zao, J.M. Wang, L.S. Ma, X.M. Shi, R.B. Guo, Y.J.(2004). Isolation and Identification of a New Cucurbitacin from Picria fel$terrae.

39 (1): 910$912

Zaoa, J.M. Wang, L.S. Niu, X.M. Sun, H.D. Guo, Y.J. (2005). Phenylethanoid Glycosides from Picria felterrae Lour. Journal of Integrative Plant Biology 47 (5): 632−636

Zaub , J.M. Wang, L.S. Guo, Y.J. Wang, Z. Wang, R.Z. (2005). A new picfeltarraenone glycoside from Picria fel$terrae. Yao Xue Xue Bao 40(1):36$8.

Zao, J.M. Wang, L.S. Ma, X.M. Guo, Y.J. Shi, R.B. (2006). A new cucurbitacin from Picria fel$terrae. J Asian Nat Prod Res. 8(4):367$71.

Zhu, Z. Zhu, S. And Wu, Z. (2004). Effect of Sodium on Blood Pressure, Cardiac Hyperthrophy, and Angiotensin Expression in Rats. American Heart Journal, 17(6): 21$24

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