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LAMPIRAN
Lampiran 1a. Hasil pengamatan gejala-gejala toksik hewan uji kelompok kontrol (pemberian Na CMC 0,5%) tiap 30 menit selama 4 jam secara intensif dan dilanjutkan pengamatan selama 14 hari
Tanda Umum Ketoksikan 0,5’ 1’ 1,5’ 2’ 2,5’ 3’ 3,5’ 4’ 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Pengamatan hari ke
Perubahan sikap terhadap pengamat - - - -
Vokalisasi, gelisah, sedasi - - - -
Kedutan, tremor, ataksia - - - -
Katatonia, paralisis, konvulsi, keterpaksaan gerak - - - -
Keberingasan, kepasifan - - - -
Anestesi, hiperastesia - - - -
Refleks serebral dan spinal Lemah, tidak ada - - - -
Kekakuan, kelembekan - - - -
Miosis, midriasis - - - -
Salivasi, lakrimasi - - - -
Sekresi lender lubang hidung - - - -
Bradipnea, dyspnea - - - -
Cheyne-Stokes breathing, kussmaul breathing - - - -
Bradikardi, aritmia - - - -
Diare, konstipasi - - - -
Flatulensi, kontraksi perut - - - -
Konsistensi tinja tidak berbentuk - - - -
Warna tinja kehitaman - - - -
Penis prolap, daerah prenial kotor - - - -
Kulit dan bulu kelembekan, kemerahan, - - - -
Pelepuhan kulit, piloereksi - - - -
Kongesti, pendarahan mulut - - - -
Sianosis, jaundice atau kekuningan - - - -
Ptosis kelopak mata - - - -
Exophthalmus, nystagmus - - - -
Opasitas - - - -
Suhu rektal subnormal, meningkat - - - -
Bengkak - - - -
Perawakan abnormal, kurus - - - -
