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Cultural Approach for Bipolar Disorder Self Help Groups

DR. Dr. Cokorda Bagus Jaya Lesmana, SpKJ (K)

Department of Psychiatry, School of Medicine, Udayana University, Bali

Bipolar Disorder

Bipolar disorder (BD) is one of the most distinct syndromes in psychiatry and has been

described in numerous cultures over the course of history. It is characterized by episodes of

depression and mania or hypomania. Most patients tend to experience predominantly chronic

depressive symptoms or recurrent depressive episodes with the result that bipolar depression

can be misdiagnosed as major depressive disorder. This can lead to inappropriate medication

choices and increased healthcare costs. It has a significant impact on quality of life, and also

on social, occupational, and cognitive functioning domains. Increased recognition of the

several burdens of BD has triggered an important change in treatment paradigms, which have

started to focus not only on symptomatic but also on causative for functional recovery.

Psychological interventions have emerged in response to studies that have shown associations

between socio-cultural environment stressors and remission–relapse cycles of bipolar disorder.

Since Kraepelin, the importance of environmental stressors in the individual

variations of the clinical course of BD has been considered (Green et al., 2014). Among those

stressors, childhood trauma has emerged as one of the most important factors associated with

negative outcomes of psychiatric disorders (Larsson et al., 2013), including BD (Watson et

al., 2014).

Childhood sexual abuse have been reported by 24% of patients with BD (Maniglio,

2013). Specifically, emotional abuse has been reported by 37% of bipolar patients, 24%

reported physical abuse, 24% emotional neglect, and 12% physical neglect. In addition,

one-third of those patients presented a combination of different types of trauma (Garno et al.,

2005).

Early life stress has been suggested to mediate vulnerability to affective disorders

(Lovallo, 2013), despite the exact mechanism of this association is not completely

understood. In line with that, a variety of studies have been relating childhood maltreatment

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Traumatic events during childhood are associated with long-term structural and functional

brain alterations (Bremner, 2002, Haldane and Frangou, 2004) especially involving

dysfunctions in prefrontal cortex, amygdala, and hippocampus (Grant et al., 2011, Lu et al.,

2013). These changes have been taking place in the pathophysiology of BD and have been

consistently related with its severity (Frey et al., 2007).

From the pathophysiological point of view, it is postulated that BD is related to

dysfunction in brain circuits involved in emotion regulation. Considering that there are

important differences in the way emotions are experienced and expressed in different

cultures, it is natural to infer that BD diagnosis and management are influenced by cultural

factors. Thus, cultural factors should be considered in designing treatment programs,

particularly in collectivistic societies (Baek et al., 2014, Vieta et al., 2011) Combining the

above developments and considerations, we propose that an expanded, culturally sensitive,

and informed deployment-focused model may be a more effective approach to the treatment

of bipolar disorder patients in non-Western cultures.

Balinese cultural elements of relevance to BD

The Balinese culture possesses a pervasive spiritually based system that emphasizes

relationships to foster solidarity and cooperation within the nuclear family, the extended

family, and the community. In Bali, family and community are tightly enmeshed and

interdependent. Children are highly respected, a respect firmly rooted in the Balinese belief

that children are reincarnated ancestors whose souls are physically reborn into the bodies of

infants. Since the souls of ancestors are highly revered and worshipped, it follows that their

reincarnated physical form is similarity honored and worshipped. Such child worship,

embedded in religious beliefs, forms the basis for the degree of respect, sustained attention,

love and devotion shown to children and appears to be a significant contributor to the

formation of secure childhood attachments to primary caregivers. Furthermore, due to the

closeness and support of both the nuclear and extended families, children tend to attach to

more than one primary caregiver, i.e. parents, older siblings, and extended family members.

As a culture-wide value, maintaining balance and control of impulses and actions is

respected, valued, and indeed expected. Any deviation from this norm would be interpreted

as inappropriate at best and as evil spirit possession at worst. Preservation of relationships

with others takes precedence over nearly all other values in society, and the abuse of children

whether physical, sexual, or psychological, would disrupt the socioculturally defined

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Traditional healing & Western psychiatry in Bali

In Bali, two types of psychotherapists exist: the Western trained psychotherapists and

the spiritual (traditional) healers, known as Balians. Although, often psychotherapists and

Balians aim at the same symptoms and problems, important differences in treatment

premises, theories, methods, techniques and modalities exist. Balians focus on the healing of

illness based on spiritual beliefs, psychotherapists on the treatment of psychobiological

disorders. Psychotherapists tend to rely on external manipulations – such as medication, cognitive or otherwise therapy – treat illness and symptoms concurrently, and view the treatment goals largely achieved when symptoms disappear. Thus after the completion of a

successful course of treatment both patients and therapists may assume a complete, or near

complete, recovery. Balians may use traditional medicine, but their main aim is to ‘‘reset’’ the body systems so that they regulate themselves harmoniously, while they regard the

process as continuing for a long time and the patient as being responsible for their own health

(Suryani and Jensen, 1993).

A culturally sensitive approach to the treatment of BD

Over the past 12 years or so, we have been developing and implementing in Bali a

treatment that integrates the above approaches into a holistic model of biopsychosocial

intervention (Lesmana et al., 2009, Lesmana et al., 2010). The model recognizes and respects the importance and interconnectedness of every person’s mind, body, and spirit, as well as the ways these elements are influenced by and in return affect, positively or negatively, one’s sociocultural relationships and religious/spiritual beliefs. Rather than following a

single-disorder treatment approach and isolating interventional foci (such as the psychobiological

focus of the psychotherapist or the spiritual focus of the Balian), our model eclectically

combines all of them, primarily at an idiographic level, in order to treat the individual as

holistically and cultural-sensitively as possible. In essence our approach is an expanded,

culturally sensitive, and informed deployment-focused model.

Through our model, patients of BD are initially clinically interviewed (ICD or DSM

interview protocols), in order to identify the presence of potentially severe symptomatology

that may require a pharmacological intervention. However, the focus of the approach is to

bring the individual back into a state of psychological balance. This is achieved through

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healing and guidance. The families are encouraged to perform purification ceremonies in

order to cleanse the spiritual burden that resulted from their exposure to the illness.

Furthermore, the patients’ families, both nuclear and extended, and communities are offered workshops, educating them on the relevant issues in a meaningful and respectful language to

their culture and local customs. Public dialogues are frequently setup, where affected families

and interested individuals are openly invited and encouraged to participate, exchange

information, and receive further advice and support. Mutual support groups are created by the

families, neighbors, counselors, and community leaders that are responsible for maintaining a

healthy communication and reporting relevant mental health state changes of community

members. The patients’ mental health state was reassessed a week after the last treatment

session, six months later, and in many instances four years thereafter. No residual symptoms

relating to their trauma have been observed in any of the patients yet.

Conclusion

Culture implementation is a potential and systematic contributor into holistic and

sensitive interventional models for the treatment of mental illness outcomes of childhood

traumatization. Mainstream psychotherapeutic approaches to BD arguably still possess

questionable levels of efficacy and external validity, which may be reduced further in the

absence of an acculturated agenda. In areas in the world, such as Bali, where a relatively

homogenous collectivistic cultural and spiritual infusion permeates all aspects of life, such

therapies need to follow an integrated, multimodal, and synergic approach to intervention.

Such an approach would mobilize modern psychotherapeutic techniques and medication,

while respecting, and responsibly utilizing the traditional health practices and religious

beliefs of the focal human geography.

In conclusion, it is our conviction that through the prudent and systematic

implementation of holistic and culturally competent strategies, a development of mental

health deployment-focused models can be achieved that offer a fair and effective service to

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References

Baek, J. H., Cha, B., Moon, E., Ha, T. H., Chang, J. S., Kim, J. H., et al. 2014. The effects of ethnic, social and cultural factors on axis I comorbidity of bipolar disorder: results from the clinical setting in Korea. J Affect Disord, 166, 264-9.

Bremner, J. D. 2002. Neuroimaging of childhood trauma. Semin Clin Neuropsychiatry, 7, 104-12.

Bucker, J., Muralidharan, K., Torres, I. J., Su, W., Kozicky, J., Silveira, L. E., et al. 2014. Childhood maltreatment and corpus callosum volume in recently diagnosed patients with bipolar I disorder: data from the Systematic Treatment Optimization Program for Early Mania (STOP-EM). J Psychiatr Res, 48, 65-72.

Dvir, Y., Ford, J. D., Hill, M. & Frazier, J. A. 2014. Childhood maltreatment, emotional dysregulation, and psychiatric comorbidities. Harv Rev Psychiatry, 22, 149-61.

Frey, B. N., Andreazza, A. C., Nery, F. G., Martins, M. R., Quevedo, J., Soares, J. C. & Kapczinski, F. 2007. The role of hippocampus in the pathophysiology of bipolar disorder. Behav Pharmacol, 18, 419-30.

Garno, J. L., Goldberg, J. F., Ramirez, P. M. & Ritzler, B. A. 2005. Impact of childhood abuse on the clinical course of bipolar disorder. Br J Psychiatry, 186, 121-5.

Grant, M. M., Cannistraci, C., Hollon, S. D., Gore, J. & Shelton, R. 2011. Childhood trauma history differentiates amygdala response to sad faces within MDD. J Psychiatr Res, 45, 886-95.

Green, M. J., Girshkin, L., Teroganova, N. & Quide, Y. 2014. Stress, schizophrenia and bipolar disorder. Curr Top Behav Neurosci, 18, 217-35.

Haldane, M. & Frangou, S. 2004. New insights help define the pathophysiology of bipolar affective disorder: neuroimaging and neuropathology findings. Prog Neuropsychopharmacol Biol Psychiatry, 28, 943-60.

Larsson, S., Andreassen, O. A., Aas, M., Rossberg, J. I., Mork, E., Steen, N. E., et al. 2013. High prevalence of childhood trauma in patients with schizophrenia spectrum and affective disorder. Compr Psychiatry, 54, 123-7.

Lesmana, C. B., Suryani, L. K., Jensen, G. D. & Tiliopoulos, N. 2009. A spiritual-hypnosis assisted treatment of children with PTSD after the 2002 Bali terrorist attack. Am J Clin Hypn, 52, 23-34.

Lesmana, C. B. J., Suryani, L. K., Tiliopoulos, N. & Jensen, G. D. 2010. Spiritual-Hypnosis Assisted Therapy: A New Culturally-Sensitive Approach to the Treatment and Prevention of Mental Disorders. Journal of Spirituality in Mental Health, 12, 195-208.

Lovallo, W. R. 2013. Early life adversity reduces stress reactivity and enhances impulsive behavior: implications for health behaviors. Int J Psychophysiol, 90, 8-16.

Lu, S., Gao, W., Wei, Z., Wu, W., Liao, M., Ding, Y., et al. 2013. Reduced cingulate gyrus volume associated with enhanced cortisol awakening response in young healthy adults reporting childhood trauma. PLoS One, 8, e69350.

Maniglio, R. 2013. Prevalence of child sexual abuse among adults and youths with bipolar disorder: a systematic review. Clin Psychol Rev, 33, 561-73.

Sala, R., Goldstein, B. I., Wang, S. & Blanco, C. 2014. Childhood maltreatment and the course of bipolar disorders among adults: epidemiologic evidence of dose-response effects. J Affect Disord, 165, 74-80.

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Vieta, E., Pappadopulos, E., Mandel, F. S. & Lombardo, I. 2011. Impact of geographical and cultural factors on clinical trials in acute mania: lessons from a ziprasidone and haloperidol placebo-controlled study. Int J Neuropsychopharmacol, 14, 1017-27. Watson, S., Gallagher, P., Dougall, D., Porter, R., Moncrieff, J., Ferrier, I. N. & Young, A. H.

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