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ABSTRAK
Seledri daun (Apium graveolens L. var. secalinum Alef.) merupakan salah satu varietas seledri, yang telah digunakan dalam penelitian oleh Suyatna 2011 sebagai afrodisiak. Efek afrodisiak berkaitan dengan aktivitas androgenik. Penelitian ini bertujuan untuk mengetahui aktivitas androgenik ekstrak seledri daun dan dosis yang memberikan aktivitas androgenik terbaik dengan metode pertumbuhan jengger (chick comb growth method) pada ayam jantan galur Hy-Line. Ayam dikelompokan secara acak kedalam lima kelompok yaitu kontrol positif (testosteron undekoat 10 mg/kg bb), kontrol negatif (PGA 1% b/v), dan tiga kelompok uji yang mengandung ekstrak seledri daun dengan dosis 50 mg/kg bb, 150 mg/kg bb, dan 250 mg/kg bb. Data penelitian dihimpun berdasarkan parameter yang diamati yaitu ukuran jengger, rasio berat jengger terhadap berat badan, rasio berat testis terhadap berat badan, berat badan, dan peningkatan berat badan. Data dianalisis secara statistik dengan ANAVA dan uji Neuman-Keuls kemudian dideskripsikan berdasarkan hipotesa penelitian. Hasil penelitian menunjukkan bahwa ekstrak seledri daun tidak memiliki efek afrodisiak melalui aktivitas androgenik pada dosis 50 mg/kg bb, 150 mg/kg bb dan 250 mg/kg bb.
Kata kunci: Apium graveolens L. var. secalinum Alef., afrodisiak, androgenik, Hy-Line
FAKULTAS FARMASI
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ABSTRACT
Leaf celery (Apium graveolens L. var. secalinum Alef.) is one of variety celery, that has been used in research by Suyatna 2011 as aphrodisiac. Aphrodisiac effect is related with androgenic activity. The purpose of this research is investigating the androgenic activity of extract of leaf celery and determining dosage that gives the best androgenic activity by using chick comb growth method at cock Hy-Line furrow. Chicken were randomly grouped into five groups, i.e. positive control (testosterone undekoat 10 mg/kg bw), negative control (PGA 1% w/v), and three experiment groups contained extract of leaf celery with dose of 50 mg/kg bw, 150 mg/kg bw, and 250 mg/kg bw. Data were collected based on the observed parameters were the size of comb, ratio of comb to body weight, ratio of testis to body weight, body weight, and body weight gained. The data were analyzed using ANOVA and Newman Keuls and then described based on the hypothesis of the research. The result showed that extract of leaf celery does not have aphrodisiac effect of androgenic activity at doses of 50 mg/kg bw, 150 mg/kg bw and 250 mg/kg bw.
Keywords: Apium graveolens L. var. secalinum Alef., aphrodisiac, androgenic, Hy-Line
