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Fig. 1. Effect of PDE inhibitors on cyclic GMP levels in hippocampal slices of the rat, in the absence (♦assayed in triplicate in a radioimmunoassay.Values which were different from control (0 M) (Student Newman–Keuls test;asterisk (*)
Fig. 2. Effect of PDE inhibitors on cAMP levels in hippocampal slices of the rat, in the presence or absence of 0.1 mM SNP, measured by aradioimmunoassay
Fig. 3. Localization of cGMP immunoreactivity in hippocampal slices incubated in vitro: (A) in the presence of 1 mM IBMX; (B) combination of 1 mMIBMX and 0.1 mM SNP; (C) 0.1 mM EHNA; (D) 0.1 mM dipyridamole; (E) 0.1 mM rolipram
Fig. 4. Localization of cGMP immunoreactivity in hippocampal slices incubated in the presence of 0.1 mM SNP and: (A) 0.1 mM vinpocetine; (B) 0.1mM EHNA; (C) 0.1 mM SKF 95654; (D) 0.1 mM rolipram; (E) 0.1 mM zaprinast; (F) 0.1 mM SKF 96231; (G) 0.1 mM dipyr
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