Supplemental Table 1. Concept set categories containing SNOMED codes for medical conditions and questions included in surveys.
Concept Set SNOMED code
Thyroid Eye Disease
Thyroid eye disease 276177000
Strabismus due to thyroid eye disease 417022003 Exophthalmos due to thyroid eye disease 416558007
Thyrotoxic exophthalmos 19885005
Exophthalmic ophthalmoplegia 69763009 Thyroid Disorder
Graves’ disease 353295004
Thyroid function tests abnormal 312399001
Thyroid atrophy 190309006
Idiopathic atrophic hypothyroidism 83664006
Goiter 3716002
Abnormal thyroid hormone 131088002
Thyroid hormone tests abnormal 166345007
Hashimoto thyroiditis 21983002
Atrophy of thyroid - acquired 237558008
Disorder of thyroid gland 14304000
Serum TSH level abnormal 166337002
Adenomatous goiter 60968001
Nodular goiter 367221000119105
Substernal goiter 66392007 Hyperthyroidism with Hashimoto disease 27538003
Nodular thyroid disease 367221000119105
Thyroid dysfunction 264580006
Autoimmune hypothyroidism 237519003
Decreased thyroid hormone level 131090001 Decreased thyroid stimulating hormone level 131017004 Increased thyroid hormone level 131089005
Raised TSH level 309080005
Multinodular goiter 237570007
Non-toxic nodular goiter 36241006
Toxic diffuse goiter 267374005
Hyperthyroidism due to ectopic thyroid nodule
87232008
Hypothyroidism due to Hashimoto’s thyroiditis
237520009
Toxic multinodular goiter 26389007
Non-toxic multinodular goiter 36241006
Diffuse thyroid goiter without thyrotoxicosis 367741000119106 Hyperthyroidism due to ectopic thyroid tissue 190255006
Thyrotoxicosis from ectopic thyroid nodule with crisis
190256007
Thyrotoxic crisis 29028009
Hypothyroidism due to fibrous invasive thyroiditis
39444001
Eyelid retraction
Bilateral eyelid retraction 11718451000119104
Left eyelid retraction 340751000119102
- Retraction of eyelid 43854003
- Retraction of lower eyelid 700264006 Retraction of upper eyelid 700344004
- Right eyelid retraction 335141000119105 Proptosis/exophthalmos
- Constant exophthalmos 89907009
- Exophthalmos 18265008
- Exophthalmos due to thyroid eye disease
416558007
- Exophthalmos of bilateral eyes 15740361000119103
Exophthalmos present 301919003
- Thyrotoxic exophthalmos 19885005
- Exophthalmos 18265008
- Exophthalmos due to thyroid eye disease
416558007
- Exophthalmos of bilateral eyes 15740361000119103
- Exophthalmos present 301919003
- Thyrotoxic exophthalmos 19885005 Diplopia/strabismus
- Diplopia 24982008
- Esotropia 16596007
- Exotropia 399054005
- Strabismus 22066006
Income
What is your annual household income from all sources?
- Less than $10,000 - $10,000-25,000 - $25,000-35,000 - $35,000-50,000 - $50,000-75,000 - $75,000-100,000 - $100,000-150,000 - $150,000-200,000 - More than $200,000 - Prefer not to answer - Skip
Employment
What is your current employment status?
- Employed for wages or self-employed
- Not currently employed for wages - Prefer not to answer
- Skip
Substance Use (Conditions)
Cigar smoking tobacco 26663004
Cigarette smoking tobacco 66562002
Number of calculated smoking pack years 782516008 Patient documented as tobacco user and
received tobacco cessation intervention
G9458
Tobacco smoking behavior - finding 365981007 Tobacco smoking consumption 266918002
Tobacco smoking status 72166-2
Alcoholism 7200002
Caffeine-related disorder 308374001
Disorder caused by alcohol 719848005
Drug dependence 191816009
Drug overdose 55680006
Drug tolerance 88320008
Finding related to substance use 409069009 Finding relating to drug misuse behavior 228366006
Marijuana user 733460004
Poisoning by cannabis derivative 15233006
Poisoning by cocaine 9982009
Poisoning by heroin 13187008 Psychoactive substance abuse 91388009 Substance Use (Surveys)
Do you now smoke a traditional cigar, cigarillo, or filtered cigar?
Do you now smoke cigarettes every day, some days, or not at all?
Do you now smoke hookah, and if so how often?
Do you now use electronic nicotine products, and if so how often?
Have you smoked at least 100 cigarettes in your entire life? (There are 20 cigarettes in a pack.) How many years have you or did you smoke cigarettes?
How often did you have a drink containing alcohol in the last year?
How often did you have six or more drinks on one occasion in the last year?
How old were you when you first started regular cigarette smoking every day?
In the past three months, how often have you used cocaine (coke, crack, etc.)?
In the past three months, how often have you used hallucinogens (LSD, acid, mushrooms, PCP, Special K, ecstasy, etc.)?
In the past three months, how often have you used inhalants (nitrous oxide, glue, gas, paint thinner, etc.)?
In the past three months, how often have you used marijuana (cannabis, pot, grass, hash, weed, etc.)?
In the past three months, how often have you used other substances?
In the past three months, how often have you used other stimulants (methamphetamine, speed, crystal meth, ice, k2/spice, bath salts, etc.)?
In the past three months, how often have you used prescription opioids for non-medical reasons (obana, fentanyl, oxycodone [OxyContin, Percocet], hydrocodone [Vicodin], methadone, buprenorphine [Supoxone], etc.)?
In the past three months, how often have you used prescription stimulants for non-medical reasons (Vyvanse, Ritalin, Concerta, Dexedrine, Adderall, diet pills, etc.)?
In the past three months, how often have you used sedatives or sleeping pills for non-medical reasons (Valium, Serepax, Ativan, Xanax, Librium, Rohypnol, GHB, etc.)?
In the past three months, how often have you used street opioids (heroin, opium, etc.)?
In your entire life, have you had at least 1 drink of any kind of alcohol, not counting small tastes or sips? (By a “drink,” we mean a can or a bottle of beer, a glass of wine or a wine cooler, a shot of liquor, or a mixed drink with liquor in it).
In your lifetime, which of the following substances have you ever used?
On a typical day when you drink, how many drinks do you have?
On average, how many cigarettes do you smoke per day now? (There are 20 cigarettes in a pack.)
On average, over the entire time that you smoked, how many cigarettes did you smoke per day? (There are 20 cigarettes in a pack.)
Are you currently prescribed medications and/or receiving treatment for other mental health or substance use condition? (Answer: Yes)
Are you still seeing a doctor or health care provider for Other mental health or substance use condition? (Answer: Yes)
Has a doctor or health care provider ever told you that you have? (select all that apply) (Answer: alcohol use, drug use, other mental health substance use)
Disability
Age <65 years old AND Answered:
What kind of health insurance or health care coverage do you have? (Answer: Medicare) OR
Are you currently covered by any of the following types of health insurance or health coverage plans? Select all that apply from one group. (Answer: Medicare)
Exclude if diagnosed with any of the following:
Human immunodeficiency virus (HIV) 86406008 End-stage renal disease (ESRD) 46177005 Amyotrophic lateral sclerosis (ALS) 86044005 Depression
Acute depression 712823008
Chronic depression 192080009
Depressive disorder 35489007
Major depression in remission 42810003 Major depression with psychotic features 726772006
Major depressive disorder 370143000
Mild depression 310495003
Mixed anxiety and depressive disorder 231504006
Moderate depression 310496002
Reactive depressive psychosis 191676002
Recurrent depression 191616006
Severe depression 310497006 Anxiety
Anxiety 48694002
Anxiety disorder 197480006
Generalized anxiety disorder 21897009
Mild anxiety 286644009
Mixed anxiety and depressive disorder 70997004
Moderate anxiety 231504006
Recurrent moderate major depressive disorder co-occurrent with anxiety
17496003 Recurrent severe major depressive disorder
co-occurrent with anxiety
16264821000119108
Severe anxiety (panic) 80583007
Exclusion Criteria
Bipolar disorder 13746004
Personality disorder 33449004
Patient Health Questionnaire 9 (PHQ-9) for Assessing Depression
1. In the past 2 weeks, how often have you been bothered by feeling bad about yourself or that you are a failure or have let yourself or your family down.
2. In the past 2 weeks, how often have you been bothered by feeling down, depressed, or hopeless.
3. In the past 2 weeks, how often have you been bothered by feeling tired or having little energy.
4. In the past 2 weeks, how often have you been bothered by little interest or pleasure in doing things.
5. In the past 2 weeks, how often have you been bothered by moving or speaking so slowly that other people could have noticed? or the opposite - being so fidgety or restless that you have been moving around a lot more than usual.
6. In the past 2 weeks, how often have you been bothered by poor appetite or overeating.
7. In the past 2 weeks, how often have you been bothered by thoughts that you would be better off dead or of hurting yourself in some way.
8. In the past 2 weeks, how often have you been bothered by trouble concentrating on things, such as reading the newspaper or watching television.
9. In the past 2 weeks, how often have you been bothered by trouble falling or staying asleep, or sleeping too much.
Scoring:
Each question scored 0-3:
0 - Not at all 1 - Several days
2 - More than half the days 3 - Nearly every day
Total Score:
0-4 No depression 5-9 Mild depression
10-14 Moderate depression
15-19 Moderately severe depression 20-27 Severe depression
General Anxiety Disorder 7 (GAD-7) Questionnaire for Assessing Anxiety
1. In the past 2 weeks, how often have you been bothered by the following problem?
Becoming easily annoyed or irritable.
2. In the past 2 weeks, how often have you been bothered by the following problem?
Being so restless that it's hard to sit still.
3. In the past 2 weeks, how often have you been bothered by the following problem?
Feeling afraid as if something awful might happen.
4. In the past 2 weeks, how often have you been bothered by the following problem?
Feeling nervous, anxious, or on edge.
5. In the past 2 weeks, how often have you been bothered by the following problem? Not being able to stop or control worrying.
6. In the past 2 weeks, how often have you been bothered by the following problem?
Trouble relaxing.
7. In the past 2 weeks, how often have you been bothered by the following problem?
Worrying too much about different things.
Scoring:
Each question scored 0-3:
0 Not at all 1 Several days
2 More than half the days 3 Nearly every day
Total Score:
Score 0-4: Minimal anxiety Score 5-9: Mild anxiety
Score 10-14: Moderate anxiety Score greater than 15: Severe anxiety
