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Indonesian Journal of

Cancer Chemoprevention

Vol.12, No.3, October 2021

The Official Journal of

Indonesian Society for Cancer Chemoprevention

ISSN : 2088-0197

Faculty of Pharmacy

e-ISSN : 2355-8989

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Indones. J. Cancer Chemoprevent., 12(3), 114-179

INDONESIAN JOURNAL OF CANCER CHEMOPREVENTION

Editor in Chief

Ferry Sandra (Faculty of Dentristry, Universitas Trisakti) Board of Editors

Adam Hermawan (Faculty of Pharmacy, Universitas Gadjah Mada)

Ari Widiyanto (Faculty of Mathematics and Natural Science, Universitas Tanjungpura) Ching-Ying F. Huang (National Yang Ming University, Taiwan)

Evamarie Hey-Hawkins (Institute of Inorganic Chemistry, Universität Leipzig, Germany) Ines Atmosukarto (Australian National University, Australian)

Masashi Kawaichi (Nara Institute of Science and Technology, Japan)

Muhammad Da’i (Faculty of Pharmacy, Universitas Muhammadiyah Surakarta) Nunuk Aries Nurulita (Faculty of Pharmacy, Universitas Muhammadiyah Purwokerto) Restu Syamsul Hadi (Faculty of Medicine, Universitas YARSI)

Solachuddin Jauhari Arief I. (International Islamic University Malaysia) Sri Handayani (Indonesian Institutes of Science)

Taifo Mahmud (Oregon State University, The USA)

Yashwant Pathak (College of Pharmacy, University of South Florida, The USA) Board of Reviewers

Adek zamrud Adnan (Faculty of Pharmacy, Universitas Andalas)

Alireza Mosavi Jarrahi (Shahid Beheshti University of Medical Sciences, Tehran, Iran) Arry Yannuar (Faculty of Pharmacy, Universitas Indonesia)

Daryono Hadi Tjahjono (College of Pharmacy, Institut Teknologi Bandung) Edy Meiyanto (Faculty of Pharmacy, Universitas Gadjah Mada) Elfahmi (College of Pharmacy, Institut Teknologi Bandung) Indwiani Astuti (Faculty of Medicine, Universitas Gadjah Mada) Jun-ya Kato (Nara Institute of Science and Technology, Japan) Koji Itahana (Duke-NUS Medical School, Singapore)

Mitsunori Kirihata (Osaka Prefecture University, Japan)

Nico P. E. Vermeulen (Vrije Universiteit Amsterdam, The Netherlands) Ratna Asmah Susidarti (Faculty of Pharmacy Universitas Gadjah Mada) Rolf F. Barth (The Ohio State University, The USA)

Sukardiman (Faculty of Pharmacy, Universitas Airlangga)

Wahyu Widowati (Faculty of Medicine, Maranatha Christian University) Yasumasa Bessho (Nara Institute of Science and Technology, Japan) Yuan Shiun Chang (China Medical University, Taiwan)

Officers

Beni Lestari (Cancer Chemoprevention Research Center, Pharmacy, UGM) Dian Anita (Cancer Chemoprevention Research Center, Pharmacy, UGM) Hilyatul Fadliyah (Cancer Chemoprevention Research Center, Pharmacy, UGM)

Nur Dina Amalina (Faculty of Mathematics and Natural Science, Universitas Negeri Semarang) Nurrani Mustika Dewi (Laboratory of Immunology, Prodia Clinical Laboratory)

Rohmad Yudi Utomo (Faculty of Pharmacy, Universitas Gadjah Mada)

Yonika Arum Larasati (Cancer Chemoprevention Research Center, Pharmacy, UGM) Editorial Office

Faculty of Pharmacy, Universitas Gadjah Mada Sekip Utara, Yogyakarta, Indonesia 55281 Telp. (+62-274) 6492662, Fax.(+62-274) 543120 Email: [email protected]; [email protected] Published by

Indonesian Society for Cancer Chemoprevention (ISCC)

Cover Picture:

“Inhibition of Human Epidermal Growth Factor Re- ceptor-2 (HER-2) from Pomelo (Citrus maxima)”

(see Muti’ah, et al., p. 148-160)

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Indonesian Journal of Cancer Chemoprevention, October 2021 ISSN: 2088–0197

e-ISSN: 2355-8989

INDONESIAN JOURNAL OF CANCER CHEMOPREVENTION ARTICLES

Citrus Flavonoids from Hydrodynamic-Cavitation Extraction of Citrus reticulata Peels Potentially Target an Autophagy Modulator, MAP1LC3A, in Breast Cancer

(Bayu Anggoro, Dennaya Kumara, Dhella Angelina, Muthi Ikawati)

Association between Vitamin D and Calcium Level and BMD Alteration in Post-Menopausal Osteoporosis Patients Treated With Bisphosphonate Therapy for at Least 1 Year in Saiful Anwar Hospital Malang

(Hamzah, Thomas Erwin Christian Junus Huwae, Chodidjah)

Addition of Beetroot Extract to Neoadjuvant Adriamycin Cyclophosphamide Regimen Increased Tumor Cell Apoptosis in Mammary Adenocarcinoma Rats

(Sri Susilowati, Neni Susilaningsih, Catharina Suharti)

Phytochemical and Bioinformatic Studies of Citrus Flavonoids as Chemopreventive Agents Targeting GGPS1 for Liver Cancer

(Ratih Kurnia Wardani, I Made Rhamandana, Christina Mutiara Putri Gono, Muthi Ikawati)

Inhibition of Human Epidermal Growth Factor Receptor-2 (HER-2) from Pomelo (Citrus maxima) Flavonoid Compounds: an In Silico Approach

(Roihatul Muti'ah, Tanaya Jati Dharma Dewi, Arief Suryadinata, Kesimira Qonita)

Bioinformatics Analysis of Rho GTP-ase Activating Protein 35 (ARHGAP35) in Breast Cancer Migration

(Dicky Rizky Febrian, Joko Setyono, Muhamad Salman Fareza, Nur Amalia Choironi, Arif Fadlan, Sarmoko)

A Mini-Review: Possible Mechanisms of Hepatoprotective Effect of Aloe Vera Gel

(Sri Handayani, Dina Aprilia, Khoirun Nisa, Vita Taufika Rosyida, Martha Purnami Wulanjati, Anjar Windarsih, Cici Darsih, Andri Frediansyah, Sari Haryanti)

114-122

123-129

130-136

137-147

148-160

161-169

170-179

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