Analyze diagnosis of animal diseases caused by virus, bac

(1)

UniversitasAirlangga

SLP

^Charge

Arimbi, drh., M.Kes., AP.Vet

(signature)

Arimbi, drh., M.Kes., AP.Vet

(signature)

(Prof.Dr. Fedik A.Rantam,drh.)

(signature) Revision Number-

Date - Faculty of Veterinary

Medicine Effective Session Begin (Odd/even) /Year

April 20^th2017 Even semester



This RPS needs to be evaluated annually

A. COURSE IDENTITY

1. Course Name Systemic VeterinaryPathology

2. Course Code KHU 104

3. Load Studies (credits) 3 credits

4. Semester V (Five)

5. Department / Prodi S-1 Bachelor of Veterinary Medicine

6. Achievement of Graduate Learning LO2 :

Analyze diagnosis of animal diseases caused by virus, bacteria, parasite, mold and toxin based on physic and laboratory examination in order to treat correc

7. Learning Outcomes Course  As a basic knowledge in the field of Animal Health

8. Course Description This course discusses about causes, pathogenesis, clinical symptoms and some forms of lesions either macroscopically / microscopicallyon integumentum, muscle and jointsystems.the respiratory system, the cardiovascular system, the digestive system, the urinary system, the male and female genital system, the nervous system, in various mammalian and ruminant animals, caused by infectious or noninfectious causes.

 Students expected to explain the pathogenesis of lesions in various organs (integumentum, muscles and joints, respiration, heart, brain, genital male and female, git and liver, urinary) due to infection agent infeksious and non infectious and several types of tumors in mammals and ruminants.

 Describe the pathogenesis of some specific diseases in some organs that are zoonotic / non-zoonotic.

 Students are expected to describe lesions both macroscopically and microscopically on various organs (integumentum, muscle and joint, respiration, heart, brain, male and female genitals, git and liver, urinary) and can predict / estimate the cause and know its pathogenesis.

9. Prerequisites (if any) Veterinary Pathology (General)

10. Head Arimbi, drh., M.Kes., AP.Vet

11. Supporting lecturer Dr.Thomas V. Widiyatno, drh., M.Kes., AP.Vet Dr.Hani Plumeriastuti, drh., M.Kes., AP.Vet Djoko Legowo, drh., M.Kes

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Week

Final Ability Expected at each stage of learning (Sub-

Achievement Courses) (C, A, P)

Study Materials Learning methods

(form of learning) Time Media Student learning experience

Assessment Criteria and Indicators (hardandsoft skills)

Value Ref.

(No.)

1 2 3 4 5 6 7 8 9 10

1 - 3

Able to explain lesion changes and describe lesions macroscopically and microscopically from mammalianand ruminantskin, and canpresent paper assignments

Able to explain lesion changes andmacroscopically and microscopicallydescribesbones and mammalian joints and ruminants, and can present paper assignments

Able to explain and describe lesions macroscopically and microscopically from mammalian muscles and ruminants, and canpresent paper assignments

Course Contract (Knowing the abscence rules, lecture and practicum, assessment system, assignment of paper) Integumentum System Pathology (week 1) explains:

1. Describes skin morphology, defense

functions and

mechanisms 2. Portal of entry 3. Describes some forms of skin lesions caused by non infectious and noninfectious agents such as congenital and heriditaries, nutrients, unknown cause.

4. Describes several specific disease lesions (contagious ecthyma, contagious papilloma leiomyoma,

Erysipela, Scabiosis, Demodexosi)

Bone and joint pathology (2nd week) explains:

1. The normal structure and function of bone and joints

2. Portal of entry

3. Bone and joint defense

Lectures and

discussions 3 X 2 X 50 '

LCD (Powerpoint)

The duties as, prepare papers, practice (practicum

of material TSB)

tasks, composing papers, practicing(practicum

of the material)

Understanding matter, discriminatinglesions

on macroscopic tissuesandmicroscopic

preparations

Understanding the material, discriminatingon the

macroscopic tissuesandmicroscopic

preparations

21.077%

(3)

mechanisms

4. Inflammatory reaction 5. The forms of bone marrow (congenital cortical hyperostosis, cranio

mandibular osteopathy) 6. Metabolic disease

(osteoporosis,

osteomalacia, ricketsia, fibrous

osteodystrophy) 7. Inflammatory forms

(acute, subacute, chronic suppurative, fibrinous chronic) 8. .Osteitis due to

infectious agents (bacteria, parasites and viruses)

9. Tumors in bone (osteoma,

chondrosarcoma etc.)

Muscular pathology (3rd week), explains:

Explain morphological changes in muscles:

1. Normal picture

2. Diagnosis of muscle

disturbance (atrophy, hypertrophy, swelling, weakness, spasm)

3. portal of entry.

4. Form of

inflammatory

mechanisms. Muscle

tasks, composing papers, practicing (practicum of the

material)

Understanding the material, discriminatinglesions

on macroscopic tissuesandmicroscopic

preparations

(4)

response to inflammation (degeneration Necrosis)

5. Forms of growth

disorders

6. Circulatory

disturbance forms in muscle.

7. Gangguan nutrition

in muscle.

8. The forms of

myopathies (myositis), caused by parasites and viruses.

9. Congenital and

hereditary disorders.

10. The forms of

neoplasia in muscle.

11. Some muscle-

specific diseases (Botulism, protozo, l myopaty pigeon fever

4-5

Can explain and to describe lesions

macroscopically and microscopically from pulmo

mammalian and ruminants, and can present paper

assignments

Pathology of Respiratory System (week 4), explains:

1. Structure and function

2. Normal flora in the respiratory tract

3. Mechanism of defense

4. Portal of entry 5. Mechanism of defense due to pathogen hematogenous

6. Pathological Changes pd

Upper respiratory tract, including:

Lecture, discussion, Questionnaire of

group seminar

2x2x50 ' LCD

(Powerpoint)

material)

Material comprehension discriminates lesions on the tissues (macroscopic) and preparation preparations

15.384%

(5)

1. Mechanism of inflammation of the nasal and sinus cord

2. Anomaly vacuum nasal

3. Inflammatory forms (fibrinous, serous,

khataral, purulendan granulomatous rhinitis) 4. Sinusitis

5. Specific diseases of cation and sinuses (EVR, equin influenza,

Strangles, IBR / red nose, 6. Feline calicilivirus (FCV)

7. The forms of neoplasia in cation and sinuses)

Advanced Respiratory System Pathology (week 5) Describes some clash changes in:

1. Pharynx, Larynx &

Trachea

Describes the lesions on:

 Degenerative diseases (laryngeal hemiplagia / paralysis)

 Gangs circulation

 Inflammatory forms (PID diphtheria, tracheitis, canine infectious

tracheobronchitis / kennel cough

 Parsit on larynx and

The understanding of matter discriminates lesions on the tissues (macroscopic) and preparatory preparations (microscopic)

(6)

trachea

 Tumors in larynx and trachea

2. Pulmo, explains the changes to:

 Congenital anomalies

 Gangs metabolism (calcinosis)

 Abnormal inflation (atelectasis, emphysema)

 Gangs of circulation (hyperemia, congestion, edema, embolism, pulmonary infarction)

3. Pattern of the lesion on the pulmo:

 Bronchi, bronchiol, alveoli

 Forms of

pneumonia (lobular, lobar, pn interstitial, granuloma)

Specific disease: hendra voirus, EVR, TBC, Mycoplasma bovis pneumonia etc.)

6

Able to explain and describe lesions on the nervous system

macroscopically and microscopically frommammalian and ruminants, and can present

paper assignments

QUIS I (lecture 1-5) Pathology Neurological Sitem (week 6), explains:

1. Organizational Structure of Neural Sisem 2. Some cells in the nervous system (morphology and function)

3. Neuron response to

Lecture, discussion, Questionnaire ofgroup seminar

1X2X50 LCD

(Powerpoint)

tasks, composing papers,practicing (practicum of the

material)

Understanding the material to discreplicatetissue lesions (macroscopic) and preparatory preparations (microscopic)

7.69%

(7)

lesions (nekrose, apoptosis) and microscopic images 4. Blood vessels (congestion, edema, cytotoxix edema / deg hydropoik on neurons, astrocytes,

oligodendroglia, 5. Some forms of edema on CNS

6. Interstitial edema 7. Spongioform 8. CNS barrier system 9. CNS Defense Mechanism

10. CNS portal of entry 11. Microglia's

response to injury (astrocytes, oligodendrosit, demyelinization) 12. Meningen response to jejas

13. - Brain traumatic (Commu sio, Contusio, Laceration)

- Anomalous Brain

(Anencephala, Hydrocephali, Hypoplasia cerebellum, Cyclops)

- Brain inflammation (Encephalitis, Encephalo myelitis, Miningoence - phalitis, Miningitis) - Encephalopatia - Encephalomalacia

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Mid SEMESTER EXAM (MSE)

7

Able to explain and describe lesions macroscopically and microscopically from the cardiovascular system of mammalian and ruminants,

and can present paper assignments

Cardiovascular System Pathology (7th Week) explain:

1. Morphology and function normally 2. Reaction to injury 3. Circulatory disorders 4. Congenital

anomalies in anjng, cats, cows and pigs)

5. Lesions on the pericardial

6. Defensive system in the cardiovascular 7. Diseases of the endocardial

(degeneration, fatty deg, degy, lifofusceonosis (brown atrophy) 8. Gangs circulation (arterial thrombus) 9. Myocardial diseases (hypertrophi)

10. Causes of necrosis (nutritional, toxic, physical,

Pathology of the vascular system:

1. Normal morphology 2. Inflammatory reaction

3. Arterial Diseases 4. Degeneration, necrosis, thrombus, embolism

Lectures, discussions, Q & A group

seminars,

1x2x50 '

LCD (Powerpoint)

tasks, composing papers, practicing (practicum of the material)

7.69%

(9)

5. Other lesions such as Aaneurysims, arterial hyperthrophy,

anteriosclerosis, arterial medial calcificcation, atherosclerosis, thrombosis, embolism, arteritis (due to bacterial infiltration, mycotic, parasitis etc. Venous ulescases dilatatium phlebitis

8-9

Able to explain and describe lesions in macroscopic and microscopic urinary systems of mammalian and ruminants,

and can present paper assignments

Pathology of the Urinary System (week 8), explains:

1. Normal &

functional structure Kidney glomerulus and tubulus (microscopic) 2. Portal of entry on the kidney

3. Sisem defense 4. Response to injury 5. Gangs of

circulation (hyperemia

& congestion, hemorrhage) 6. Infarction.

7. Several lesions / diseases of the kidney

 Abnormal growth (hypoplasia, dysplasia)

 Diseases of Glomerulus, glomerulitis (embolic nephritis, viral, chemical glomerulitis).

 Membranous glomerulonephritis.

Lectures, discussions, FAQs, group

seminars

2 x 2 x50 '

LCD (Powerpoint)

material)

15.384%

(10)

 Glomerulosclerosis, amyloidosis

Pathology in the kidney tract (week 9), explains:

Disease of the tubules:

1. Azotemia and uremia

2. Acute renal necrosis

3. Acute tubular necrosis (the cause, its

pathogenesis and microscopic picture) 4. Explaining the pathological pathology of tubulointerstitialis:

 Interstitial nephritis

 Granulomatous nephritis

 Pyelonephritis

 Hydronephrosis

 Chronic Renal Disease

Explain:

1. Lower & Urinary tract.

2. Urolitiatis Acute cystitis, chronic, cystitis.

3. Hydroureter &

hydrourethra) 4. Mycotic cystitis 5. Btk neopla sia pd vu (epithelial Tumors, mesenchymal tmr) 6. Parasites in the

(11)

kidneys.

10-12

Able to explain and describe lesions macroscopically and microscopically digestive system and biliary system of

mammalian and ruminants, and can present paper

assignment

Pathology Oral cavity - stomach (week 10), explains:

Describes oral changes of the oral cavity:

1. Structure and function

2. The digestive system in the digestive tract

3. Portal of entry

Pathology in oral cavity:

1. 1. perturbation disorders (palatoschisis, cheiloschisis)

2. 2. Stomatitis &

gingivitis 3. 3.Vesicular Stomatitis 4. FMD 5. 5.Vesicular exanthema 6. 6.Erosive &

Ulcerative Stomatitis 7. Necrotizing Stomatitis

8. (calf diphtheria) 9. Ulcerative gingivitis.

10. Noma

11. Gingival

hyperplasia, epulis.

12. Btk-btk

neoplasia (squamous cell carcinomas, melanomas,

seminars.

3x 2x 50 '

LCD (Powerpoint)

tasks, composing papers, practicing (practicum of the material)

23.077%

(12)

canine oral pappilomatosis, fibrosarcomas)

Pathology Changes in Teeth

1. Malocclusions (prognathia,

brachygnathia)

2. Anomalies of Tooth devl (toothsasis,

dentigerous cysts).

3. Abnormal coloration of teeth.

Pathological Changes Ex.Saliva :

Sialoadenitis, Ranula, Sialolith andbtk2 Neoplasia

Perubhan patol.pd.Tongue (histology

normal and function) 1. Gangguaqn pertbhan (lethal

glossopharyngeal defc).

2. Systemic diseases (wooden tongue, thrush).

3. Epithelial hyperplasia.

4. Parasites (sarcocystis spp., Trichinella spiralis)

Pathological changes of the esophagus (normal histology and function)

seminars.

(13)

:

1. Subscription

pertbhan (cricopharyngeal achlasia, congenital megaesophagus) 2. Parasites in the esophagus

3. Incarcerated lesions: (esophageal dilation, choke) 4. The forms of Neoplasia

Menjlskan change

Rumen, reticulum and omasum pathology

1. Bloat / ruminal tympany

2. Foreign bodies 3. Btk inflammation:

Rumenitis, bacterial &

mycotic.

4. Ruminal papillomas

Changes in Gastric &

Abomasum Pathology:

1. Gastric dilatation &

volvulus syndrome 2. Abomasal displacement

3. Dilatation & rupture 4. Btk inflammation (gastritis & abomasitis, braxy).

5. Ulcer & erosion, Uremic gastritis.

(14)

6. Pyloric stenosis.

7. Parasites often found

Intestinal Pathology (week 11), explains:

1. Btk-btk cells pd intestine 2.Mechanisne bowel sound 3.Patogenesis of diarrhea and its consequences 4. Ggan pertbhan (meckels diverticulum, megacolon) 5.Btk-2 blockage

(enteroloith, strictures &

obstructions, intussusception intestinal displacement) 6. Volvulus & torsion 7.Diverticula

8. Btk patolg akbt parasites (Strogylus vulgaris, amebiasis,

Coccidiosis, ascariasis, hookworm disease, tricuriasis, cestodes, oesophagustomum).

9. Btk patolg akbt bacterial infection (collibacilosis, Salmonellosis,Chlostridial enteritis, Paratubercullosis).

10. Btk patolg akbt inf virus (TGE, Swine dysentery, BVD,

parvovirus enteritis, FIP) Biliary system pathology (week 12), explains

(15)

1. An

overview of histology and normal function 2. Portal of entry

3. Mechanism of hepatic lesions 4. Pattern of inflammation 5. Liver response to rdg (regenersi, fibrosis, cerrhois and akbtnya) 6. Ihterus 7. Explain the liver rdg reaction (btk necrosis)

8. Btk patolg pd ductus biliverus &

gallbladder:

cholangiocellular 9. Adenoma / carcinoma, biliary obstruction, Cholelithiasis, cholecystitis.

10. Liver parasites (coccidiosis, distomatosis)

Pancreatic Pathologic Changes:

Normal histology and function

- Pancreatic calculi,

-pancreatic

(16)

degeneration

-acute & chronic

pancreatitis

13- 14

Able to explain and describe lesions in macroscopic andmicroscopic systems Reproduction of Animal Female and Male from mammalian and ruminansia,

and can present paper assignment

Quis 2

Reproductive Pathology of Female andMales (week 13) explains:

Explain the pathological changes of btn

reproduction:

Disorders of the ovaries 1. Anomalies (cysts, hydatides) 2. The form of neoplasm (ovarian teratoma)

Uterine disorders 1.

Inflammation (endometritris, piometra)

2. Non

inflmatori (cystic endometrial hyperplasia, torsio, prolap)

3. Tumors (leiomyoma of the uterus)

4. Abnormal torsiononinflamation (torsion, prolapse, subinvolution)

pathologic vagina & vulva:

1.Inflamasi (postparturient

seminars

1 x 2 x 50 '

LCD (Powerpoint)

tasks, composing papers,practicing (practicum of the material)

The understanding of matter discriminates lesions on thetissues (macroscopic) and preparatory preparations (microscopic)

7.69%

(17)

vulvitis &

vaginitis ,, granular vulvitis) 2.Infectious pustular, vulvovaginitis.

4. Btk-2 Neoplasia (transmissible veneral tumor / TMT, squamous cell carcinoma)

Describe BTK cervix pathological pd:

 Btk anomaly

 cervicitis

Menjlskan inflammatory BTK:

1.bacterial, (Campylobacter fetus, Bruselosis

etc), Fungi, Virus, Protozoa.

Menjlskan BTK tubular uterine pathologic pd:

hydrosalpinx, salpingitis, pyosalpinx

Menjlskan inflammation of the breast (mastitis):

 An overview of histology and function

 Portal of entry

 Some causes of mastitis, mastitis forms:

 Coliform mastitis

 Mycoplasma mastitis

 Granulomatous mastitis

(18)

 Tuberculosis mastitis

Explain reproductive pathology of male reproduction:

1. Anatomical arrangement and histology

2. Portal of entry

3. Defense system

4. Anomaly shape:

1.Cryptorchidism 2.Hypoplasia Inflammatory forms

 Testicular degeneration

 Orchitis, epididimitid

 Neoplasia (germ cell neoplasm, leydig cell tumors, sertoli cell tumors.

Explain the pathological pathway to scrotum & tunica vaginalis:

1. btk anomaly (scrotal dermatitis

2. neoplasia) papilloma)

Describe BTK pathological spermatic cord (vas

deferens):

1. Varicocele

(19)

2. Sertolli cell tumors

3. Torsio 4.

Inflammation (funisitis, scierrhous cord)

Menjlskan BTK pathological testis and epididymis

1.

Epididymitis, orchitis 2. Seminal vesiculitis

Pathology on gld Prostate 1. Prostatic hyperplasia 2. Prostate carcinoma

3. Prostatitis

Pathology to Penis and prepuce:

1. Form of bnormality (persistent prenulum)

2.

Inflammation (phallitis), balanitis, palaphostitis / balanophostitis 5. Tumors (penile fibro papilloma,

transmissible venous

(20)

tumor, Squamos cell carcinoma

LSE

C.REFERENCESLIST

Analyze diagnosis of animal diseases caused by virus, bac

SLP

This RPS needs to be evaluated annually

Analyze diagnosis of animal diseases caused by virus, bacteria, parasite, mold and toxin based on physic and laboratory examination in order to treat correc

Mid SEMESTER EXAM (MSE)

1

Gavin. MD, James FZ 2016. Pathologic Basis of Veterinary Disease. Five Edition. MOSBY ELSEVIER. St. Louis. Missouri

2

Thomsons . Special Veterinary Pathology. M c . Gavin, MD, Carton, W and Zachary, J Edition 3. 2001.

3

Veterynary Phatology. Jones, T and Hunt, RD., Fifth edition .1983.

4

Soft Skill Development of Airlangga University Student 2008.

5

Systematic Pathology Practical Guidebook - FKH Airlangga University