Moro PL Olson CK, Zhang B, Marquez P, Strid P. Safety of booster doses of coronavirus disease 2019 (COVID-19) vaccine in pregnancy in the Vaccine Adverse Event Reporting System. Obstet Gynecol 2022;140.
The authors provided this information as a supplement to their article.
©2022 American College of Obstetricians and Gynecologists. Page 1 of 3
Appendix 1. Coronavirus Disease (COVID-19) Booster Vaccine Coverage Among Pregnant People Aged 18-49 Years, United States Month Year Median Booster Vaccine Coverage Percenta (%) 2022 Contributing Week Ending Dates
Sep 2021 0.29 9/25, 10/2
Oct 2021 0.88 10/9, 10/16, 10/23, 10/30
Nov 2021 1.92 11/6, 11/13, 11/20, 11/27
Dec 2021 2.54 12/4, 12/11, 12/25, 1/1
Jan 2022 2.62 1/8, 1/15, 1/22, 1/29
Feb 2022 2.52 2/5, 2/12, 2/19, 2/26
Mar 2022 2.39 3/5, 3/12, 3/19, 3/26
Data from the Centers for Disease Control and Prevention. COVID-19 vaccination among pregnant people aged 18-49 years overall – Vaccine Safety Datalink, United States. Accessed May 3, 2022. https://covid.cdc.gov/covid-data-tracker/#vaccinations-pregnant-
womenaProduct%20of%20the%20median%20monthly%20vaccine%20coverage%20during%20pregnancy%20and%20booster%20coverage%20a mong%20fully%20vaccinated%20women%2018-49%20in%20the%20United%20States
Moro PL Olson CK, Zhang B, Marquez P, Strid P. Safety of booster doses of coronavirus disease 2019 (COVID-19) vaccine in pregnancy in the Vaccine Adverse Event Reporting System. Obstet Gynecol 2022;140.
The authors provided this information as a supplement to their article.
©2022 American College of Obstetricians and Gynecologists. Page 2 of 3
Appendix 2. Provisional 2021 Live Births and 2020 Fetal Deaths in United States
Month Year Live Births With Boostera Fetal Deaths With Boosterb,c Live Births and Fetal Deaths With Booster
Sep 2021d 282 1 283
Oct 2021 2767 14 2782
Nov 2021 5766 30 5796
Dec 2021 7875 42 7917
Jan 2022 7257 45 7303
Feb 2022 6714 42 6756
Mar 2022e 5585 32 5617
TOTAL 36247 207 36454
Note: Live birth and fetal death values represent the number of monthly births or deaths multiplied by the product of the median monthly vaccine coverage and booster coverage among fully vaccinated women 18-49 in the United States, described in Supplemental Table 1.
aNational Vital Statistics System, National Center for Health Statistics, CDC. State and National Provisional Counts, Monthly and 12 month-ending number of live births, deaths and infant deaths: United States. Accessed May 2, 2022. https://www.cdc.gov/nchs/nvss/vsrr/provisional-
tables.htm
bNational Vital Statistics System, National Center for Health Statistics, CDC. Vital Statistics Online Data Portal – 2020 Fetal Deaths Data Files.
Accessed May 2, 2022. https://www.cdc.gov/nchs/data_access/vitalstatsonline.htm
cFetal deaths ≥20 weeks by obstetric estimate among United States births to women 15-49
dStudy period began September 22, 2021, therefore, 9 of 30 days of September births are contributing.
eStudy period ended March 24, 2022, therefore, 24 of 31 days of March births are contributing.
Moro PL Olson CK, Zhang B, Marquez P, Strid P. Safety of booster doses of coronavirus disease 2019 (COVID-19) vaccine in pregnancy in the Vaccine Adverse Event Reporting System. Obstet Gynecol 2022;140.
The authors provided this information as a supplement to their article.
©2022 American College of Obstetricians and Gynecologists. Page 3 of 3
Appendix 3. Rate of Stillbirths and Preterm Deliveries Observed, Vaccine Adverse Event Reporting System, September 22, 2021–March 24, 2022
Outcome Observed Rate (per 100,000)a
Stillbirth (≥20 weeks gestation) 5 13.7
Preterm delivery 2 5.5
aStillbirth rate per 100,000 live births and fetal deaths. Preterm delivery rate per 100,000 live births.