ATOM INDONESIA
Author's Responses
Article : #515
Name of All Authors : I.Mahendra, I.Daruwati, T.Hafiz A.W, W.Nuraeni
Article Title : THE EFFECT OF CALCIUM CARBONATE AND CHOLECALCIFEROL ON PHARMACOKINETICS INTERACTION OF
99mTc-CTMP
RADIOPHARMACEUTICALS FOR BONE SCANNING IN RATS (Rattus norvegicus)
E-mail : [email protected]
Line # Referee’s Comments Author's Responses
12
Is that realy necessary to put three decimal for this result. Consider just two decimal would be enough.
Look up for other paper with the same topic!!! Has been revised
12
I think this abstract requires a few more lines explaining what is the implication for the imaging result when distribution half time and excretion/
elimination time is getting longer than expected!!
There is no publication that explain about the implication for the imaging result when distribution half time and excretion/ elimination time is getting longer than expected. Explaination on the discussion
205
Please make sure to which data the validating data was compared!!! Was to to previous experiment or to control group data or to both? I think it’s better to compare and discuss the current results to control group data first and then to previous result which has been published.
Has been revised
205
This part need to be re-written as 99mTc-CTMP injcected to control group rats and to the treated rats has similar radiochemical purity!!!
Has been added radiochemical purity data in previous experiment, because radiochemical purity in repeating eperiment better than previous experiment.
320
Similar comment with Abstact. I think this discussion requires a few more lines explaining what is the implication for the imaging result when distribution half time and excretion/ elimination time is getting longer than expected!!
There is no publication that explain about the implication for the imaging result when distribution half time and excretion/ elimination time is getting longer than expected.
But, author add the possibility for implication symptomps when Technetium or phosphonate getting longer in the body based on the case.
334
It might need a few more line which state the future
direction of this research!! Has been revised