SDC table 3. Quality Assessment of the 18 Included Cohort Studies According to the Newcastle-Ottawa Scale (22)
Study
Selection of Study Participants Comparability of the Groupsa Assessment of the Outcome of Interest (1)
External Validity (Interve
ntion) Cohortb
(2) Selection
of the Nonexpose
d Cohortc
(3) Ascertainmen
t of the Interventiond
(4) Incident
Disease
e
Total Stars, No.f
(A) Unsatisfactor y Colposcopy
(B) Age, Parity, and
Dysplasia
Total Stars, No.f
(1) Assessment
of Outcomeg
(2) Length
of Follow-
uph
(3) Adequac
y of Follow-
upi
Total Stars, No.f
Bornstein et al (33) A* A* A* A* 4 ... … 0 B* A* D 2
Bretelle et al (34) B* A* A* B 3 … Yes* 1 B* A* A* 3
Fanning and Padratzik (35)
A* A* A* A* 4 … … 0 A* B D 1
Hillemanns et al (36)
A* B A* A* 3 … Yes* 1 B* B D 1
Huang and Hwang (37)
B* A* A* B 3 … Yes* 1 B* A* A* 3
Husseinzadeh and Retting (38)
B* A* A* A* 4 … Yes* 1 B* A* C* 3
Ioffe et al (39) A* A* A* A* 4 Yes* Yes* 2 A* B D 1
Kainz et al (40) B* B A* A* 3 … Yes* 1 B* B D 1
Kim et al (41) B* A* A* A* 4 Yes* Yes* 2 D B D 0
Murta et al (42) A* A* A* A* 4 Yes* Yes* 2 B* A* C* 3
Oyesanya et al (43) B* A* A* A* 4 Yes* Yes* 2 B* A* A* 3
Petry et al (44) B* B A* A* 3 … Yes* 1 B* A* D 2
Pires et al (45) B* A* A* A* 4 … … 0 B* B D 1
Reinthaller et al (46)
B* A* A* A* 4 … Yes* 1 B* B D 1
Saidi et al (47) A* A* D A* 3 Yes* Yes* 2 B* A* A* 3
Schermerhorn et al (48)
B* A* A* A* 4 … Yes* 1 B* A* A* 3
Simmons et al (49) A* A* A* B 3 Yes* Yes* 2 B* A* A* 3
Zeng et al (50) A* A* A* B 3 … … 0 B* A* B* 3
a Comparability of cohorts on the basis of the design or analysis: (A), study controls for the most important factor (unsatisfactory colposcopy in each group of treatment); and/or (B), study controls for any additional factor (age, parity, degree of CIN or dysplasia).
b A, Truly representative of the average histology-proven cervical intraepithelial neoplasia (CIN) patient at risk for progression and/or recurrence of the disease; B, somewhat representative of the average CIN patient at risk for recurrence and/or progression of the disease; C, selected group; D, no description of the derivation of the cohort.
c A, Drawn from the same source as the intervention cohort (concurrent controls); B, drawn from a different source (historical controls); C, no description of the derivation of the nonexposed cohort.
d A, Secure record (eg, surgical records); B, structured interview; C, written self-report; D, no description.
e Asterisks indicate stars. A study can be awarded 1 star for each item within the Selection category (maximum, 4 stars), the Comparability category (maximum, 2 stars), and the Outcome category (maximum, 3 stars).
f Demonstration that outcome of interest was not present at the start of the study: A, yes; B, no.
g A, Independent blind assessment; B, record linkage; C, self-report; D, no description.
h Follow-up was long enough for outcomes to occur: A, yes; B, no.
i A, Complete follow-up and all participants were accounted for; B, participants lost to follow-up were unlikely to introduce bias because small numbers were lost and more than 80% had follow-up, or description was provided of those lost; C, follow-up rate less than 80%, and there was no description of those lost; D, no statement.
