Kelompok 4 Kelompok 4
The
Regulation of
Blood
Pressure
Blood
Pressure
New AHA Classification on
2017
MENURUT RISKESDAS 2018
63.309.620 427.2
18
Terdapat
kasus hipertens i
dengan kematian
Short Term (secs-
mins) Intermediate
Term (min-hours)
Long Term (day- years)
Blood Pressure Regulation
• Baroreceptor
• Chemoreceptor
• CNS ischemic response
• Capillary fluid shift
• Stress relaxation
• Renal body fluid mechanism
• RAAS
Locations
• Aortic arch (10
th)
• Carotid sinus (9
th)
Range : 60-200 mmHg Hypertension →
baroreceptor treshold ↑
Baroreceptor
s
Locations
• Aortic body (10
th)
• Carotid body (9
th)
Range : 40 - 100 mmHg MBP
Respond to :
• Hypoxia
• Hypercapnia
• Acidosis
Chemoreceptors
Capillary Fluid
Shift
Stress Relaxation
↑ BP Blood
vessels stretched
Increase
capacity d ↓BP
Renal Body Fluid Mechanism
Renin Angiotensin
Aldosterone System(RAAS)
● Unger, T., Borghi, C., Charchar, F., Khan, N. A., Poulter, N. R., Prabhakaran, D., Ramirez, A., Schlaich, M., Stergiou, G. S., Tomaszewski, M., Wainford, R. D., Williams, B., & Schutte, A. E.
(2020). 2020 International Society of Hypertension Global Hypertension Practice Guidelines.
Hypertension, 75(6), 1334–1357. https://doi.org/10.1161/hypertensionaha.120.15026
● Whelton, P. K., Carey, R. M., Aronow, W. S., Casey, D. E., Collins, K. J., Dennison Himmelfarb, C., DePalma, S. M., Gidding, S., Jamerson, K. A., Jones, D. W., MacLaughlin, E. J., Muntner, P., Ovbiagele, B., Smith, S. C., Spencer, C. C., Stafford, R. S., Taler, S. J., Thomas, R. J., Williams, K. A., & Williamson, J. D. (2018). 2017
ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Hypertension, 71(6). https://doi.org/10.1161/hyp.0000000000000065
● Whelton PK, Carey RM, Aronow WS, Casey DE Jr, Collins KJ, Dennison Himmelfarb C,
DePalma SM, Gidding S, Jamerson KA, Jones DW, MacLaughlin EJ, Muntner P, Ovbiagele B, Smith SC Jr, Spencer CC, Stafford RS, Taler SJ, Thomas RJ, Williams KA Sr, Williamson JD, Wright JT Jr. 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA guideline for the prevention, detection, evaluation, and management of high blood pressure in adults: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. J Am Coll Cardiol 2018;71:e127–248.
Sources
Thank
You