Born onsite (yes or no): Mode of birth (vagi

(1)

Table, Supplemental Digital Content 2: Data Collection Form.

Identification number:

Born onsite (yes or no):

Mode of birth (vaginal, caesarean section):

Gender (male or female):

Gestational age (weeks):

Gestational age category:

- Very preterm (< 32) - Extremely preterm (≤ 28) Birth weight (g):

Birth weight category:

- Very low birth weight (<1500g) - Extremely low birth weight (<1000g) Small for gestational age (yes or no):

APGAR score at 1 and 5 minutes (1-10):

Congenital chromosomal abnormality (present or absent):

Patent ductus arteriosus (yes or no):

CRIB-II score:

Neonatal sepsis (yes or no):

Necrotising enterocolitis requiring surgery (yes or no):

Intraventricular haemorrhage (yes or no):

Grade of intraventricular haemorrhage (grade 1-4):

Maternal age during pregnancy (years):

Plurality (singleton or multiple birth):

Birth order (if multiple birth):

Infant received fresh breastmilk (yes or no):

If yes infant age at start of feeding (days):

Donor human milk received (yes or no):

If yes infant age at start of donor milk feeding (days):

CMV-negative donor breastmilk (yes or no):

Age at diagnosis of CMV infection (days):

Postmenstrual age at diagnosis (weeks):

Mode of laboratory diagnosis (PCR or culture):

Sample used for diagnosis (urine, saliva, blood, CSF):

Viral load at diagnosis (copies/mL):

Congenital CMV infection excluded (yes or no):

Sample used to exclude congenital infection (dried blood spot, urine, saliva, blood, CSF):

Signs/symptoms of CMV infection (present or absent):

Symptoms of CMV infection within 14 days before/after diagnosis:

Thrombocytopenia 21 days either side of diagnosis:

New onset (yes or no):

Neutropenia 21 days either side of diagnosis:

(2)

Elevated GGT 21 days either side of diagnosis:

Elevated ALT 21 days either side of diagnosis:

Elevated AST 21 days either side of diagnosis:

Elevated total bilirubin 21 days either side of diagnosis:

Elevated conjugated bilirubin 21 days either side of diagnosis:

Symptoms of CMV infection within 14 days before/after diagnosis:

Abdominal distension:

CMV-SLS:

Stool colour change:

Vomiting:

Hepatomegaly or hepatosplenomegaly:

Petechiae:

Loose stool:

Jaundice:

Pneumonitis:

CMV-SLS (present or absent):

Blood cultures within 14 days before/after diagnosis (positive, negative, absent):

Antiviral therapy received (yes or no):

If yes type of antiviral therapy (ganciclovir or valganciclovir):

Dose of antiviral therapy (mg):

Age at start and duration of antiviral therapy (days):

Multiple courses received (yes or no):

Viral load after antiviral therapy (copies/mL):

Symptoms resolved after antiviral therapy (yes or no):

Adverse effects of antiviral therapy (yes or no):

Mortality (yes or no):

If yes age at death (days):

Postmenstrual age at death (weeks):

Cause of death:

Length of hospital stay (days):

Age and gestational age at discharge (days/weeks):

Duration of mechanical ventilation (days):

Bronchopulmonary dysplasia (present or absent):

Retinopathy of prematurity (yes or no):

Stage of retinopathy of prematurity (stage 1-4):

Hearing screen result (passed, failed, referred):

Neurodevelopmental follow-up at 1 year (yes or no):

Developmental score at 1 year:

Neurodevelopmental impairment (NDI) at 1 year (yes or no):

Neurodevelopmental follow-up at 2 years (yes or no):

Developmental score at 2 years:

(3)

NDI at 2 years (yes or no):

Hearing at follow-up: