sex age operation time (min) Blood (ml)
CAD/CAM 1 M 18 298 248
CAD/CAM 2 M 18 231 219
CAD/CAM 3 F 21 265 169
CAD/CAM 4 M 20 204 140
CAD/CAM 5 F 22 227 270
CAD/CAM 6 F 16 189 75
CAD/CAM 7 F 26 196 195
CAD/CAM 8 F 22 217 322
CAD/CAM 9 M 18 329 528
CAD/CAM 10 F 19 184 124
CAD/CAM 11 M 20 168 215
CAD/CAM 12 M 18 212 144
CAD/CAM 13 M 20 176 95
CAD/CAM 14 F 28 216 116
sex age operation time(min) Blood(ml)
conventional 1 M 23 164 199
conventional 2 M 44 186 253
conventional 3 F 19 263 528
conventional 4 F 22 223 120
conventional 5 F 19 200 59
conventional 6 F 19 178 136
conventional 7 F 29 197 90
conventional 8 M 24 198 200
conventional 9 F 41 247 252
conventional 10 M 16 169 182
p value 0.26 0.96
Table S1: Patient information
All patient information was showed. The parameter was sex, age, operation time and the amount of blood loss.
Facial type simulating reposition
Skeletal Class
Verticall y
M2-right U1 M2-left
CAD/CAM 1 3 long
5mm Sup. , 1.5mm Ant.
6mm Sup.
5mm Sup. , 1.5mm Post.
CAD/CAM 2 3 long 4mm Sup. no change 3mm Sup.
CAD/CAM 3 2 long 5mm Sup. 5mm Sup. 5mm Sup.
CAD/CAM 4 3 average 3mm Ant. 3mm Ant. 3mm Ant.
CAD/CAM 5 3 long 5mm Sup. no change 3mm Sup.
CAD/CAM 6 3 long 2mm Sup. , 3mm Ant. 2mm Sup. , 3mm Ant. 2mm Sup. , 3mm Ant.
CAD/CAM 7 3 average 0.5mm right
1.5mm Sup. , 0.5mm right
3mm Sup. , 0.5mm right
CAD/CAM 8 3 long 6mm Sup. 3mm Sup. 6mm Sup.
CAD/CAM 9 3 short 2mm Sup. , 4mm ant. 2mm Inf. , 4mm Ant. 2mm Sup. , 4mm Ant.
CAD/CAM 10
3 long
3mm Sup. , 1.5mm Ant.
3mm Sup.
3mm Sup. , 1.5mm Post.
CAD/CAM 11
3 long 3mm Ant. 3mm Ant. 3mm Ant.
CAD/CAM 12
3 short 3mm Sup. , 5mm Ant. 3mm Ant. 3mm Sup. , 1mm Ant.
CAD/CAM 13
3 average 3mm Ant. 3mm Ant. 3mm Ant.
CAD/CAM 14
3 average 3mm Sup. , 2mm right 2mm right 3mm Sup. , 2mm right
Table S2: The other Patient information in CAD/CAM group
The patient information of CAD/CAM group was showed about facial type (diagnosis) and simulating reposition (treatment plan). The complicated(rotational) reposition was CAD/CAM 1,2,5,7,8,9,10,12,14. Sup.: superior, Ant.: anterior, Post.:
posterior, Inf.: inferior.
Facial type simulating reposition
Skeletal Class
Verticall y
M2-right U1 M2-left
conventional 1 3 average 3mm Sup. no change 1mm Sup.
conventional 2 3 short 5mm Ant. 5mm Ant. 5mm Ant.
conventional 3 2 long 6mm Sup. 6mm Sup. 6mm Sup.
conventional 4 3 long 3mm Sup. , 3mm Ant. 3mm Sup. , 3mm Ant. 3mm Sup. , 3mm Ant.
conventional 5 3 short 2mm Sup. no change 5mm Sup.
conventional 6 2 long
1.5mm Sup. , 1.5mm Ant.
1.5mm Sup. , 1.5mm Ant.
1.5mm Sup. , 1.5mm Ant.
conventional 7 3 short 4mm Sup. 2mm Inf. 4mm Sup.
conventional 8 1 short 5mm Sup. no change 3mm Sup.
conventional 9 3 long 3mm Sup. 3mm Sup. 3mm Sup.
conventional 10
2 average 5mm Sup. , 3mm Ant. 3mm Sup. , 3mm Ant. 5mm Sup. , 3mm Ant.
Table S3 The other Patient information in conventional group
The patient information of conventional group was showed about facial type (diagnosis) and simulating reposition
(treatment plan). The complicated(rotational) reposition was conventional 1,5,7,8,10. Sup.: superior, Ant.: anterior, Post.:
posterior, Inf.: inferior.
No. 1 2 3 4 5 6 7 8 9 10 11 12 13 14
P- value
horizontal axis
CAD/CAM - 0.38
- 1.02
0.68 0.06 - 1.07
1.11 - 1.94
1.34 - 0.14
1.53 - 0.03
1.46 1.26 1.24
0.949 conventio 1
nal
0.47 - 0.62
1.83 0.74 - 2.32
0.86 0.57 0.64 - 0.61
0.32
vertical axis
CAD/CAM 0.7 0.55 0.22 - 0.51
1.12 - 2.21
0.06 0.52 - 1.27
1.13 0.36 - 1.99
- 0.91
-
0.13
0.008 conventio
nal
3.8 - 2.49
2.8 - 3.64
- 0.45
- 1.27
2.29 0.35 -2.8 - 0.24
anteroposte rior axis
CAD/CAM 1.62 1.25 - 0.99
-1.6 0.96 - 1.06
1.73 - 0.25
- 2.41
-0.5 0.98 - 2.98
- 1.52
-
0.02 0.364 9 conventio
nal
- 0.08
- 3.17
2.55 -1.4 0.42 0.08 1.77 - 2.63
4 - 2.86
3D
CAD/CAM 1.81 1.7 1.22 1.68 1.82 2.69 2.59 1.46 2.73 1.97 1.05 3.87 2.17 1.25
0.004 4 conventio
nal
3.83 4.08 4.2 3.97 2.4 1.54 2.95 2.73 4.92 2.89
Table S4: The error between simulation data and post-operative CT to dental cast data at U1.
The most error of U1 was anteroposterior axis in CAD/CAM group, and vertical axis in conventional group. The vertical axis was significant difference between CAD/CAM and conventional groups (p=0.008). But, horizontal and anteroposterior axis
were no significant difference between these groups. (unit: mm)
No. 1 2 3 4 5 6 7 8 9 10 11 12 13 14
P- value
horizontal axis
CAD/CAM - 0.57
- 2.52
0.54 - 0.09
- 0.82
- 1.46
- 1.61
- 0.05
- 0.54
0.14 - 0.26
0.78 0.23 0.08
0.265 conventio 5
nal
0.86 1.19 0.99 0.37 - 2.55
1.32 -0.2 1.3 - 1.61
0.38
vertical axis
CAD/CAM - 0.24
0.03 1.48 0.95 - 1.47
- 0.98
- 2.42
- 0.34
- 1.51
0.11 - 1.95
2.06 -1.5 -
0.41 0.565 conventio 2
nal
1.79 - 1.07
- 1.37
- 2.11
- 1.27
- 0.86
0.21 0.25 -4.4 - 0.99
anteroposte rior axis
CAD/CAM 1.31 - 0.21
- 1.02
- 1.55
0.73 - 3.37
1.43 - 1.41
- 2.72
- 2.33
- 0.12
- 1.77
- 2.42
-1.2
0.890 7 conventio
nal
0.1 - 1.07
1.72 - 1.16
0 0.55 0.61 - 2.26
3.03 - 3.04
3D
CAD/CAM 1.45 2.52 1.87 1.82 1.83 3.8 3.24 1.45 3.15 2.34 1.97 2.83 2.86 1.27
0.870 5 conventio
nal
1.98 1.93 2.41 2.43 2.85 1.67 0.67 2.62 5.58 3.22
Table S5: The error between simulation data and post-operative CT to dental cast data at M2-right.
The most error of M2-right was anteroposterior axis in CAD/CAM group, and vertical axis in conventional group. The horizontal, vertical and anteroposterior axis were no significant difference between these groups. (unit: mm)
No. 1 2 3 4 5 6 7 8 9 10 11 12 13 14
P- value
horizontal axis
CAD/CAM - 0.59
- 3.42
0.53 -0.1 -0.8 - 2.77
- 1.65
- 0.02
- 0.52
0.22 - 0.25
0.49 0.12 -
0.05 0.651 conventio 1
nal
0.87 1.18 0.88 0.32 - 2.58
1.31 - 0.26
1.21 - 1.16
0.39
vertical axis
CAD/CAM - 1.15
- 0.73
1.17 - 0.04
- 0.54
- 2.51
- 0.35
- 1.04
- 0.23
- 0.84
- 2.18
- 0.61
- 1.27
-1.5
0.769 conventio 6
nal
1.87 1.75 - 3.05
- 1.13
- 1.21
- 0.63
1.47 0.06 0.37 -0.9
anteroposte rior axis
CAD/CAM 1.48 2.65 - 0.77
- 1.39
0.45 2.17 1.39 0.66 - 1.68
- 0.32
0 - 0.49
-0.7 0.6
0.029 6 conventio
nal
- 0.54
- 3.86
2.93 - 0.14
0.46 -0.2 2.27 -3.4 5.47 - 3.12
3D
CAD/CAM 1.96 4.39 1.5 1.39 1.07 4.32 2.18 1.23 3.15 0.92 2.19 1.68 1.46 1.62
0.032 6 conventio
nal
2.14 4.4 4.33 1.18 2.88 1.46 2.72 3.61 5.61 3.27
Table S6: The error between simulation data and post-operative CT to dental cast data at M2-left.
The most error of M2-left was anteroposterior axis in CAD/CAM and conventional groups. And, there was significant difference between these groups (p=0.0296). But, horizontal and vertical axis were no significant difference between these
groups. (unit: mm)