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Anti-carcinogenic activity of Gynura procumbens Extract through cytochrome P450 and Glutathione S-transferase

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Name Dr. Iwan Sahrial Hamid, DVM., MSi.

Position 3rd and 4st Semester, Veterinary Pharmacology

Academic career Doctorate, Veterinary Science, Gadjah Mada University, 2010 Master, Immunology, Universitas Airlangga, 2000

Undergraduate, Veterinary Medicine, Universitas Airlangga, 1990 Employment Senior lecturer, Fac. Veterinary Medicine, Universitas Airlangga Research and

development projects over the past five years

1. Antiangiogenesis Activity Test of Tin Leaf (Ficus Carica L.) On The Number of Blood Vessels And VEGF Ekspression of Chorioallantoic Membrane of Embrionated Chicken Eggs.

2. Anticancer Activity of Centella asiatica Leaves Extract in Benzo(a)pyrene-Induced Mice.

3. Gene p53 Mutations after the Induction of 7,12 Dimethylbenz(a)anthracene (DMBA) and Administration of Anti- Carcinogenesis Properties of Gynura procumbens in Sprague Dawley Rats.

4. Mixture Sambiloto (Andrographis panniculata Nees.) end Salam (Syzigium polyanthum (Wight) Walp) Extract to Improve GLUT4 ang PPAR-γ Expression in Hyperglicemic Wistar Rats.

5. Evaluation of Anti-angiogenic antivity of Centella asiatica water ekstrak on chick embryo chorioallantoic membrane induced by bFGF.

6. Anti-carcinogenic activity of Gynura procumbens Extract through cytochrome P450 and Glutathione S-transferase.

7. Ethyl p-methoxycinnamate from Kaemferia galanga Inhibits Angiogenesis Through Tyrosine Kinase.

8. Study biocompatibility and osteogenic differentiation potential of human umbilical cord mesenchymal stem cells (hUCMSCs) with gelatin solven.

Cooperation with industry over the past five years

Project name Partner(s)

Patent and protected right

name

Publications

- Antiangiogenesis Activity Test of Tin Leaf

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(Ficus Carica L.) On The Number of Blood Vessels And VEGF Ekspression of Chorioallantoic Membrane of Embrionated Chicken Eggs. European Journal Of Oncolog Pharmacy Vol.1 (4). 2018.

Author.

- Anticancer Activity of Centella asiatica Leaves Extract in Benzo(a)pyrene-Induced Mice. International Journal of Pharmacognosy and Phytochemical Research.2016. Vol.

8 No.1. pp. 80-84. Author.

- Gene p53 Mutations after the Induction of 7,12-Dimethylbenz(a)anthracene

(DMBA) and Administration of Anti-Carcinogenesis Properties of Gynura procumbens in Sprague Dawley Rats. J. Biomedical Engineering. Vol.1 No.1. 2015. Co-author.

- Mixture Sambiloto (Andrographis panniculata Nees.) end Salam (Syzigium polyanthum (Wight) Walp) Extract to Improve GLUT4 ang PPAR-γ Expression in Hyperglicemic Wistar Rats. Proceeding 1st International Seminar on Natural Resources Biothecnology : From Local to Global. September 8-9 2015.

Fakultas Teknobiologi Universitas Atma Jaya Yogyakarta. Co- author.

- Evaluation of Anti-angiogenic antivity of Centella asiatica water ekstrak on chick embryo chorioallantoic membrane induced by bFGF. Indonesian Journal of Cancer Chemoprevention. Vol. 4, No. 1, Tahun 2014. Hal. 463-469.

Author.

- Anti-carcinogenic activity of Gynura

procumbens Extract through cytochrome P450 and Glutathione S- transferase. International Juornal of Pharm Tech Research. Vol.8 No.1 pp. 24-29 Tahun 2015. Co-author.

- Ethyl p-methoxycinnamate from Kaemferia galanga Inhibits Angiogenesis Through Tyrosine Kinase. Universa Medica. Vol. 34, No. 1, Tahun 2015. Hal. 43-51. Co-author.

- Study biocompatibility and osteogenic differentiation potential of human umbilical cord mesenchymal stem cells (hUCMSCs) with gelatin solven. J. Biomedical Science and Enginering. Vol 8. pp.

420-428. Juli. Tahun 2015. Co-author.

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Participation in specialist

organisations over the past five years

1. Perhimpunan Dokter Hewan Indonesia 2. Ikatan Farmakologi Indonesia

3. CCRC (Cancer Chemopreventif Research Center)

Referensi

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