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Correlations between Insulin Receptor Substrate-1 and Key Kinases in Diabetic Rats Treated with Puguntano Leaf Extract

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Data will be presented in the form of tables and graphs, as well as the results of the expression of the PGE2 gene. It is in line with the results of this study that the high ΔCq value of the PGE2 gene in the osteoarthritis synoviocyte control group will reduce the expression of the PGE2 gene [12].

Figure 1. Morphology cells; A) 24-hour synoviocyte cell; B) 48-hour  synoviocyte  cell;  C)  MSC-WJ  24  hours;  D)  MSC-WJ  48  hours;  E)  synoviocyte co-culture MSC-WJ 24 hours; F) synoviocyte co-culture  MSC-WJ 48 hours
Figure 1. Morphology cells; A) 24-hour synoviocyte cell; B) 48-hour synoviocyte cell; C) MSC-WJ 24 hours; D) MSC-WJ 48 hours; E) synoviocyte co-culture MSC-WJ 24 hours; F) synoviocyte co-culture MSC-WJ 48 hours

Acknowledgment

The results of this study reinforce previous research conducted by Bull et al., (2012) who stated that the effect of mesenchymal stem cells on explants of cartilage cells obtained from patients with knee osteoarthritis grade IV can reduce the expression level of the prostaglandin E2 gene by 50%. This study may explain the influence of Wharton Jelly mesenchymal stem cells on osteoarthritis synoviocytic cells through PGE2 gene expression parameters which play an important role in the inflammatory process in the pathogenesis of osteoarthritis.

Quantification of mesenchymal stem cells in the mononuclear cell fraction of bone marrow samples obtained for cell therapy. Mesenchymal stem cells secrete factors that inhibit inflammatory processes in short-term osteoarthritic synovium and cartilage explant culture.

Introduction

The fundamental role of estrogen and progesterone receptors in breast cancer prognosis and therapy management is well known and established. This new metabolic pathway represents the main source of estrogen and circulating androgen levels are involved in the rising rates reported for breast cancer.

Results

Sections examined were reported as positive for HER-2/neu with a score of 3+; cases with greater than or equal to 10% tumor cells showed intense complete membranous staining [19]. Sections examined were reported as AR-positive when more than 1% of tumor cells showed positive nuclear immunostaining [22], [23].

Discussion

Park et al., [6] revealed a significant correlation between AR expression and both histological type and grade. Qi et al., [33] found no significant correlation between AR expression and patient age and N stage.

The Difference of Serum Gastrin-17 Level Based on Gastritis Severity and Helicobacter Pylori Infection

Mann Whitney U test was used to determine the difference in serum Gastrin-17 levels based on H. Finally, we found a significant difference in serum Gastrin-17 level based on gastritis severity and H.

Table 1: Baseline characteristics
Table 1: Baseline characteristics

The Effect of Mesenchymal Stem Cell Wharton's Jelly on ADAMTS-4 and iNOS Levels in Osteoarthritis Rat Model

The immunosuppressive ability of MSC is shown by the increase in nitric oxide (NO) products which play a major role in inhibiting T-cell proliferation [10]. Inducible nitric oxide synthase induced MSC after activation by IFN IF and TNFα, IL-1α or IL-1β.

Material and Methods

Decreased levels of ADAMTS-4 in the group treated with MSC-WJ from the control group. Increased levels of iNOS in the group treated with MSC-WJ from the control group.

Figure  1:  Data  on  Characteristics  of  Mesenchymal  Stem  Cells  Wharton Jelly;  A)  Cells MSC-WJ reach  confluence
Figure 1: Data on Characteristics of Mesenchymal Stem Cells Wharton Jelly; A) Cells MSC-WJ reach confluence

The Impact of Goal-Directed Fluid Therapy in Prolonged Major Abdominal Surgery on Extravascular Lung Water and

This is most likely due to the significant reduction in fluid requirements in the GDT group. Although patients in the GDT group received less intraoperative fluid, they had higher MAP compared with the control group.

Figure 1: CONSORT chart showing patient recruitment; GDT: goal- goal-directed therapy
Figure 1: CONSORT chart showing patient recruitment; GDT: goal- goal-directed therapy

The Role of Presepsin in Patients with Acute Surgical Diseases

The median prothrombin index in blood plasma decreased with an increase in intra-abdominal pressure (IAP). The mean concentration of the sCD14 biomarker of the control group is 246 ng/ml (Figure 4).

Table  1  shows  the  median  and  standard  deviation (SD) of these markers by groups
Table 1 shows the median and standard deviation (SD) of these markers by groups

Comparison of Contrast Enhanced Low-Dose Dobutamine Stress Echocardiography with 99mTc-Sestamibi Single-Photon

A head-to-head comparison of the individual segments in this study showed a 78.6% agreement between contrast-enhanced low-dose dobutamine stress echocardiography and ECG-gated myocardial SPECT. Similarly, Panza et al., reported dysfunctional segments without perfusion, but they thought this was due to the error.

Table 1: Baseline characteristics of the study population
Table 1: Baseline characteristics of the study population

Values and Correlations between C-Reactive Protein and Apolipoprotein B after Treatment with Methotrexate at Patients

Lipids, myocardial infarction, and ischemic stroke in patients with rheumatoid arthritis in the apolipoprotein-related mortality risk study (AMORIS). Lipid profile and cardiovascular risk in patients with rheumatoid arthritis: effect of disease and drug therapy.

Table 1: Patients and controls characteristics
Table 1: Patients and controls characteristics

Efficacy of Albendazole and Mebendazole With or Without Levamisole for Ascariasis and Trichuriasis

Combination of albendazole combined with levamisole showed better cure rate for mild trichuriasis (95.8%) than albendazole treatment (46.2%) and mebendazole + levamisole (83.3%), p = 0.00. Based on Table 6, the combination of albendazole with levamisole showed better cure rate for mild trichuriasis (95.8%) than albendazole treatment (46.2%) and mebendazole combined with levamisole (83.3%), p = 0.01.

Table 1: Characteristics of Subjects
Table 1: Characteristics of Subjects

Sexual Function in Iranian Female Multiple Sclerosis Patients

In their study, Ghajarzadeh et al., reported a negative and significant correlation between the total score of sexual dysfunction and the BDI score in MS patients [13]. In conclusion, the results of this study showed a significant association between depression and sexual dysfunction in the MS population.

Table  1:  Comparison  of  personal  properties  in  cases  and  controls groups
Table 1: Comparison of personal properties in cases and controls groups

Acknowledgements

Factors associated with sexual dysfunction in individuals with multiple sclerosis: Implications for assessment and treatment. Impact of sexual dysfunction on health-related quality of life in people with multiple sclerosis.

Correlation between Obesity and Lipid Profile in Type 2 Diabetes Mellitus Patients at the Endocrine and Metabolic Polyclinic in

LITAF is a TNF-α description of the regulator that should play a role in the immune mechanism against infection. The release of free fatty acids from endothelial lipoprotein from triglycerides, which increases the rise of lipoprotein β, causes lipotoxicity, which also interferes with the function of insulin receptors.

Table 1: Basic characteristics of research subjects
Table 1: Basic characteristics of research subjects

Acknowledgement

This release of free fatty acids from too much triacylglycerol can also inhibit fat synthesis and reduce the clearance of triacylglycerol. Free fatty acids also contribute to hyperglycemia by reducing the consumption of glucose by insulin-stimulated muscles.

The Association between Asthma and Obesity in Children – Inflammatory and Mechanical Factors

There was a significant difference between the patients from the three groups in the mean values ​​of the following non-specific inflammatory markers: a) Eosinophilia-elevated values ​​above normal (> 4%) were detected in children with asthma, both with normal and high asthma. BMI compared with overweight children without asthma (p. In addition, to avoid bias due to small sample size, obese patients were included in the overweight group.

Table 1: Demographic characteristics of the patients
Table 1: Demographic characteristics of the patients

Refractive Status in Children with Laser-Treated Retinopathy of Prematurity: Our Experience in Bulgaria

The aim of our study was to analyze the long-term refractive status in children 3.5 years after laser treatment for type 1 prethreshold ROP.

Patients and Methods

Astigmatism progression in early treatment retinopathy of prematurity study up to 6 years of age. Refractive and ocular biometric profile of children with a history of laser treatment for retinopathy of prematurity.

Multi-Modal Analgesic Technique for Pain Control in Patients Undergoing Diagnostic Gynecological Laparoscopy

Randomized Controlled Clinical Trial

A multimodal analgesic technique using a combination of two simple and safe methods (intraperitoneal local anesthetic and pulmonary recruitment) as analgesia for pain after laparoscopy has not yet been discussed. Therefore, the aim of this study was to investigate the effect of a multimodal analgesic technique on postoperative pain after diagnostic gynecological laparoscopy, in order to exploit the advantages of both techniques compared with intraperitoneal instillation of lidocaine alone and lung recruitment maneuver alone.

Patients and Method

In the lidocaine group, VAS 1 was 5 (4-6), which was better than that of the pulmonary group. Randomized clinical trial of the impact of the pulmonary recruitment maneuver on the reduction of shoulder pain after laparoscopy.

Figure 1: Flow diagram for the patients in the trial
Figure 1: Flow diagram for the patients in the trial

Serum Vascular Endothelial Growth Factor in Egyptian Obese Women with Insulin Resistance

It has been previously demonstrated that VEGF is responsible for much of the angiogenic activity of adipose tissue [13]. However, according to a population-based cross-sectional study, it was observed that VEGF has a small effect on the development of atherosclerosis [16].

Subjects and Methods

In the present study, significantly increased serum VEGF levels were observed in obese IR women compared to the control group (p < 0.05). In the current study, a significantly higher concentration of VEGF was found in obese IR patients.

Table  1:  Clinical  and  biochemical  characteristics  of  obese  women with IR and healthy controls
Table 1: Clinical and biochemical characteristics of obese women with IR and healthy controls

Declarations

In addition, higher levels of VEGF were observed in patients with type -1 diabetes compared to healthy controls [33]. Significantly increased levels of VEGF were found in cases of metabolic syndrome compared to healthy controls [34].

Comparison of the Effects of Albumin 5% versus Ringer's Lactate on Blood Loss and Coagulation after Vascular Surgery

In-TEM clot formation time measured in seconds; there was no statistically significant difference between the two groups p = 0.77. In-TEM Maximum clot strength measured in mm had no statistically significant difference between the two groups P = 0.085.

Figure 1: CONSORT Flow Diagram
Figure 1: CONSORT Flow Diagram

Goldenhar Syndrome: A Case Report

Case Report

Goldenhar syndrome is a congenital disorder known as dysplasia/oculo-auricular-vertebral (OAV) syndrome with the classic triad syndrome of mandibular hypoplasia (facial asymmetry), ear malformation (microtia/anotia and preauricular fistula) and/or eyes (bulbar dermoid cyst). , microphthalmia), as well as vertebral anomalies [7]. This case was first reported in 1952 by Maurice Goldenhar [1], [2]. In conclusion, patients with Goldenhar syndrome may have multiple congenital abnormalities and should be thoroughly evaluated with other multidisciplinary.

Figure 1: The face is not symmetrical
Figure 1: The face is not symmetrical

Giant Pelvic Neurofibroma in Patient with Plexiform Sciatic Neurofibroma and Neurofibromatosis Type 1

Clinical display of numerous café-au-lait spots on the skin of the upper limbs. The presence of neurofibromas in the course of the iliac vessels on the right, where the largest measures 75/49 mm (Figure 3a).

Figure 1: A), B) Clinical examination: in the area of the genitals, the  gluteal region and the upper medial part of the right hip, a plexiform  tumour-like  formation  with  a  darker-skin-colour  appearance,  which  resembles  clinically  as  "worm
Figure 1: A), B) Clinical examination: in the area of the genitals, the gluteal region and the upper medial part of the right hip, a plexiform tumour-like formation with a darker-skin-colour appearance, which resembles clinically as "worm

Surgical Management (Microsurgery) of Traumatic Penile Amputation: A Case Report

Next, microvascular re-anastomosis of the left dorsal artery and only one dorsal vein was successfully performed. Correlation of the number of repaired arteries or veins with skin loss did not provide a clear conclusion.

Figure 1: Complete penile amputation at the base of the penis A  detailed  discussion  regarding  surgical  reimplantation  of  the  amputated  penile  stump  was  undertaken
Figure 1: Complete penile amputation at the base of the penis A detailed discussion regarding surgical reimplantation of the amputated penile stump was undertaken

Cerebellar Cryptococcal Abscess in HIV-Negative Patient: A Case Report and Literature Review

Case Presentation

Multiple hypointense lesions in the left cerebellar hemisphere on T1W1, hypertensive on T2W1 and limited to DW1, with contrast-enhancing rim. Invasive fungal infections are estimated to cause more than 1.5 million deaths per year worldwide - the majority of cases occurring in immunocompromised patients [3].

Figure  1:  Head  MRI.  Multiple  hypointense  lesions  in  the  left  cerebellar  hemisphere  of  T1W1,  hypertense  on  T2W1  and  restricted  to  DW1,  with  contrast  enhancement  rim
Figure 1: Head MRI. Multiple hypointense lesions in the left cerebellar hemisphere of T1W1, hypertense on T2W1 and restricted to DW1, with contrast enhancement rim

Case Report: A Simple Thoraco - Abdominal Flap to Reconstruct Wide Defect of Radical Mastectomy in Squamous Cell Carcinoma

To cover the defects on the medial side of the TA flap, a split-thickness skin graft from the left thigh was used. Pure primary squamous cell carcinoma of the breast: a rare presentation and clinicopathological comparison with common ductal carcinoma of the breast.

Figure 1: Lump with an ulcer on the left breast
Figure 1: Lump with an ulcer on the left breast

Clinical Behaviour and Marginal Sealing of Bulk-Fill Resin Composite Restorations Using Light Amplified High-Intensity

Clinical evaluation of the restorations Assessments of the restorations were done at baseline (one week after placement of the restoration), after 6 and 12 months using the modified US Public Health Service (USPHS) criteria [14], [15] . Results of clinical evaluation of the restorations (Marginal discoloration) At baseline, all restorations showed a score of 0 (100%).

Table 1: Eligibility criteria of the trial
Table 1: Eligibility criteria of the trial

Alveolar Cleft Reconstruction Using Different Grafting Techniques

This study included twenty-four patients who had a unilateral cleft and required alveolar cleft grafting. It showed that the ability of stem cells to treat large alveolar cleft defects is safe.

Figure 1: Iliac crest technique (left); Bone marrow stem cells trocar  (right)
Figure 1: Iliac crest technique (left); Bone marrow stem cells trocar (right)

Influence of Motivation on Academic Performance among Dental College Students

Correlations between the Motivation Task Value Subscale and Academic Performance according to student characteristics. Correlations between Test Anxiety Motivation Subscale and Academic Performance by Student Characteristics.

Table 1: Comparison of mean composite scores for motivation  strategy among the study participants (n=175)
Table 1: Comparison of mean composite scores for motivation strategy among the study participants (n=175)

Analysis of Nitrosamines in Processed Meat Products in Medan City by Liquid Chromatography-Mass Spectrometry

Material and Method

In Figure 2, it can be seen that the obtained calibration curve has a linear relationship between peak area and concentration. In figure 3 it can be seen that the obtained calibration curve has a linear relationship between peak area and concentration.

Table  1:  Tailing  Factor with  different  ratio  of  mobile  phase  for  analysis of NDEA, NMTCA, and NTCA
Table 1: Tailing Factor with different ratio of mobile phase for analysis of NDEA, NMTCA, and NTCA

The Content of Extracellular Nucleic Acids in the Blood and Ejaculate of Men of Reproductive Age Living in the Ecologically

The content of extracellular nucleic acids in the blood and ejaculate of men of childbearing age living in ecological. The subjects of the study were the blood and ejaculate of men of reproductive age living in the regions of the Aral Sea.

Table  1:  Indicators  of  extracellular  nucleic  acids  in  blood  plasma in men (M ± m)
Table 1: Indicators of extracellular nucleic acids in blood plasma in men (M ± m)

A Study of Noise Pollution Measurements and Possible Effects on Public Health in Ota Metropolis, Nigeria

H0: The effects of the noise pollution level are the same for morning, afternoon and evening. In conclusion, further analyzes of the noise pollution level in the Ota metropolis have been provided in this study.

Figure 1: Summary report for morning measurements on LNP
Figure 1: Summary report for morning measurements on LNP

The Link Between HIV Knowledge and Prophylaxis to Health Professionals

There is an increasing trend in wearing gloves before manipulating and using syringes with increasing work experience of the health professional (p = 0.01). 55.9% of respondents reported that transmission of the virus from an HIV-infected patient during a syringe injection accident to a healthcare professional was > 75%.

Table 1: Job profile of participants in the survey
Table 1: Job profile of participants in the survey

Impact of Pharmacist Intervention on Improving the Quality of Life of Patients with Type 2 Diabetes Mellitus

The quality of life of the patients with T2DM before and after interventions by pharmacists is shown in Table 3. Only 36% of the patients with T2DM had a good quality of life in the pre-intervention group.

Gambar

Figure  2:  A)  AR-positive  nuclear  expression  (X200  original  magnification) in HER-2 enriched breast  carcinoma; B) ER-negative  nuclear  expression  (X200  original  magnification);  C)  PR  negative  nuclear expression (X200 original magnification)
Table 1: Clinicopathological findings and their correlation with  androgen receptors expression
Table 1: Baseline characteristics
Figure  1:  Data  on  Characteristics  of  Mesenchymal  Stem  Cells  Wharton Jelly;  A)  Cells MSC-WJ reach  confluence
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