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CV Dr. Hani 2012

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Curriculum Vitae of

Dr.

HANI ZAKARIA ASFOUR

Personal Details:

Name: Hani Zakaria Asfour Date of birth: 11/05/1974 Gender: Male

Marital Status: Married

Permanent Address: Jeddah, Saudi Arabia

Work Address: P.O Box - 80205 Jeddah 21589, Saudi Arabia E-mails: hasfour@hotmail.com

Contact Numbers: 02-6400000 (Ext. 22122, 18471), Home: 02-6919182 Mobile: 00966506255504

Current Positions:

Vice Dean for Pharmacy School at King Abdualziz University, Jeddah, Saudi Arabia

Deputy Director for Finance and Administrative Affairs of Princess Al- Jawhara Center for Excellence in Research of Hereditary Disorders

Supervisor for Academic Affairs, School of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.

Assistant professor at Medical Parasitology Department, King Abdulaziz University, Jeddah, Saudi Arabia.

Lap supervisor at Princess Al-Jawhara center of excellence in research of hereditary disorders

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Previous Positions and Experience:

2006-2008

Assistant Professor, Chairman of Medical Biology Department, School of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.

2003-2006

Teaching assistant, Biology Department, University of North Texas, U.S.A 2000 - 2002

Did Masters in Molecular Biology (Microbial Genetics) from College of Art and Sciences, University of North Texas, Denton, Texas, USA

1998-1999

Teaching Assistant, Medical Biology Dept, School of Medicine, King Abdulaziz University

When I was teaching assistant at King Abdulaziz University Faculty of Medicine, Department of Medical Biology, I was teaching and supervising tutorials of small group teaching, and laboratory classes for specialization for first year Medical students, Dentistry, Pharmacy, and Medical Technology students.

I was also responsible for teaching "Principle of Microbiology" for several undergraduate students at the University of North Texas, Biology Department.

Current Licenses and Certification :

2006 - Ph.D. Molecular Biology (Microbial Genetics), College of Art and Sciences, University of North Texas, Denton, Texas, U.S.A.

2002 - M.S. Molecular Biology (Microbial Genetics), College of Art and Sciences, University of North Texas, Denton, Texas, USA.

1997 - B.Sc. Microbiology,(Honor) College of Science, King Abdulaziz University, Jeddah, Saudi Arabia

International Memberships :

1) Active Member of American Society of Microbiology 2) Member of Saudi Biological Society (SBS)

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3) Arab Association for Optimal use of Antibiotics

National & Local Committees :

 Member of Main Task Force Committee for Academic Accreditation of Faculty of Medicine, KAU

 Head, Committee for Academic accreditation of Faculty of Medicine (Medical Students)

 Head of Sport Committee, College of Medicine 1429 – 1431

 Head, Committee for Academic Affairs, college of Pharmacy

 Member of curriculum committee, college of Pharmacy

 Head of laboratory committee, college of Pharmacy

 Member of Medicine Academic Affairs Committee

 Member of Medical colleges Admission & Registration Committee

 Member of Medical Genetic Module

Medical Education Research Interest and Experiences :

イAssessing student's achievements in undergraduate medical training.

ロStudy Guide: their uses and preparations.

Additional Professional Activities

 During the past years my research emphasis was placed on:

 Pyrimidine Metabolism in Bacteria with special focus on the Regulatory Eenzyme, Aspartate Transcarbamolase (ATCase).

 All Pyrimidine Enzymes Assays, using different techniques such as Spectrophotometer.

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 The role of Pyrimidine Enzymes in the regulation of the Pyrimidine pathway and other Chemical pathways.

 Genetic organization and biochemistry of prokaryotic DNA.

 Practical application of Polymerase Chain Reaction (PCR)

 Through these research projects I obtained knowledge and techniques in recombinant DNA technology, amplifying of cloned gene, bacterial strain construction, Making competent cells, transformation, selection and purification of wild type and mutant ATCase by using affinity chromatography. .

The focus of my master and Ph.D research was on pyrimidine metabolism in bacteria with special emphasis on the regulatory enzyme. In my master thesis my research was focused in the study of the regulatory enzyme Aspartate transcarbamoylase (ATCase) in Pseudomonas putida. In this project I dealt with the purification and kinetic characterization of mutant and wild type Pseudomonas putida ATCase. During that time I experienced different techniques such as, strain construction, making competent cells, transformation, selection, and purification of ATCase by using ionic exchange column. In addition to that, techniques in cell biology were also experienced by taking a practical course.

The main focus in my Ph.D research was to study the relation between different mutants in the pyrimdine genes and the production of virulence factors in the opportunistic pathogen, Pseudomonas aeruginosa. This study showed that all mutant strains were deficient in the production of virulence factors. Low level production of pyocyanin, hemolysin, casein protease, and elastase were found in the mutant strains compared to the wild type strain. Swimming, swarming, and twitching motility were also impaired. Many different techniques were experienced during that time including the following:

polymerase chain reaction (PCR) and its different application, hybridization, Southern blot, gel electrophoresis, DNA isolation, Protein purification, and construction of mutant strain.

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International Training and Workshops :

Attended training on "DISCOVERY COURSES IN MEDICAL EDUCATION", at Center for Medical Education, University of Dundee. UK. 20-24 Jul 2009

Workshops and conference Attended :

 Course of study in the skills and techniques of " EFFECTIVE PERSONAL PRODUCTIVITY". Organized by LEADERSHIP MANAGEMENT

INTERNATIONAL, INC. Hilton, Jeddah from Apr.01.2012-May.13.2012

 Workshop on " Leadership and Management in Medical Education" at King Abdulaziz University, Medical Education Department, Faculty of Medicine, 04 June -05th June 2011.

 Presented a lecture on Basic genetics on"Intensive Course And Workshop In Basic Medical Genetics" at Princess Al-Jawhara Center for Excellence in Research of Hereditary Disorders during May 2-3, 2011

 Attended the workshop entitled " Recruiting, Developing, and Retaining a Faculty for the Twenty-First Century" organized by Academic Leadership Center, Ministry of Higher Education, during January, 04-05, 2011.

 Attended training in " Strategies for Success in Proposal Writing " organized by King Abdulaziz City for Science and Technology, Riyadh, Saudi Arabia, during Oct. 30-31. 2010.

 Attended the “Strategic Management Skills” training program under Center for Teaching & Learning Development at King Abdulaziz University, on 01-03 March, 2010

 Training course for "Innovation Management" during the 5th Quality Day Program at King Abdulaziz University, April 29, 2008

 6th Arab conference for the optimal use of Antibiotics, Morroco 2008

 Workshop on "Effective Assessment of Student Performance" at King Fahd Medical Research Center, King Abdulaziz University, Jeddah. KSA, (08-13 March 2008.)

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 Study Guides: Their Uses and Preparation (22 April 2007, School of Medicine King Abdulaziz University.)

 Conference about "An Introduction to Center Of Excellence In Genomic Medicine Research (CEGMR)" at King Fahad Research Center, King Abdulaziz University on 2nd June 2007.

 Communication Skill ( 23June- 4July 2007, King Abdulaziz University)

 Workshop of Essential Skills for Medical Education Course, 3-4 Sep 2007, King Abdulaziz University, School of Medicine.

 6th GCC Medical Education conference held at King Abdulaziz University, Jeddah, KSA 25-26 Shawal 1428/ 6-7 November, 2007

Publications :

.

1. Faidallah HM, Rostom SA, Asiri AM, Khan KA, Radwan MF, Asfour HZ.

(Dec, 2011). 3-Cyano-8-methyl-2-oxo-1,4-disubstituted-1,2,5,6,7,8- hexahydroquinolines. synthesis and biological evaluation as antimicrobial and cytotoxic agents. Journal of Enzyme inhibition and Medicinal Chemistry.

2. Yassien, M., Asfour, H. (Nov, 2011). Production of α-amylase by Streptomyces species isolated from West Area of Saudi Arabia. Journal of Pharmacy Research, Vol. 4 (12), pp 4393-4395

3. Hani Z. Asfour, Mohamed H. AlQahtani, Khaled A. Balto and Sufian M.

ElAssouli. (July 2011). Heat shock proteins, estrogen and progesterone receptors expression in breast carcinoma, Journal of medicine and medical science, Vol. 2(7), pp.977-984.

4. Alaa Hadhoud, Azza M. Abdulaziz, Hani Z. Asfour and Ahmed M. Alhejin.

(January,2011). Imp-1 Metallo Beta-Lactamase Producing Pseudomonas aeruginosa and Resistance to Antibiotics, Egyption Journal of Medical Microbiology, Vol(20) No(1), 191-198.

5. Asfour H. (April, 2009). Metallo Beta-Lactamases in Clinical Pseudomonas aeruginosa Isolate and Carbapenem Resistance, Zagazig University Medical

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6. S. A. Cope, T.C. Spigener, J. L. Huneycutt, P. Ralli, H. Asfour and G. A.

O’Donovan (2007). Pyrimidine Auxotrophy is Synonymous with Decreased Virulence in Pseudomonas aeruginosa, Abstract B-488 Abstract 107th Annual Meeting American Society for Microbiology

7. Asfour, H. (2006). Regulation of pyrimidine biosynthesis and virulence factor production in wild type, Pyr- and Crc- mutants in Pseudomonas aeruginosa. Ph.D. Dissertation. University of North Texas. U.S.A

8. Asfour, H. (2002). Effector response of the aspartate transcarbamoylase (ATCase) from wild type Pseudomonas putida and a mutant with 11 amino acids deleted at the N-terminus of PyrB. M.S. Thesis. University of North Texas. U.S.A

9. J. A. Meixner, D.A. Beck, C.G.A. Maier, H. Asfour, and G.A. O’Donovan (2002). Pyrimidine salvage schemes in soil bacteria. Abstract K-82, p.

281, Abstract 102nd Annual Meeting, American Society for Microbiology

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