40 DAFTAR PUSTAKA
Al-Quran dan Terjemahannya. 2014. Jakarta: Departemen Agama RI.
Arisuryanti T dan Daryono BS. Genetika Populasi. Yogyakarta: Fakultas Biologi Universitas Gadjah Mada. 2007
Chowbay B, Zhou S, Lee E. 2005. An interethnic comparison of polymorphisms of the genes encoding drug-metabolizing enzymes and drug transporters:
experience in singapore. LDMR. 37(2):327-378.
Deguchi T. Sequences and Expression oAf lleles of Polymorphic Arylamine N- Acetyltransferase of Human Liver. THE JOURNAL OF BIOLOGICAL CHEMISTRY. 1992;267(25):18140-18147.
Dorland,W.A Newman. 2011. Kamus Saku Kedokteran Dorland. Jakarta:EGC Global Tuberculosis Report 2015. World Health Organization. . Geneva: WHO.
2015
Katzung, Bertram G. Basic & clinical pharmacology 10 th ed. McGraw Hill Lange ebook. San Fransisco.2016.
Kita T, Tanigawara Y, Chikazawa S, Hatanaka H, Sakaeda T, Komada F et al. N- Acetyltransferase2 Genotype Correlated with Isoniazid Acetylation in Japanese Tuberculous Patients. Biol Pharm Bull. 2001;24(5):544-549.
Kubota R, Ohno M, Hasunuma T, Iijima H, Azuma J. Dose-escalation study of isoniazid in healthy volunteers with the rapid acetylator He of arylamine N- acetyltransferase 2. European Journal of Clinical Pharmacology.
2007;63(10):927-933.
Perhimpunan Dokter Paru Indonesia. Pedoman Diagnosis & Penatalaksanaan di Indonesia. Jakarta: PDPI. 2006.
Ponchel, Frederique et al. "Real-Time PCR Based On SYBR-Green I Fluorescence:
An Alternative To The Taqman Assay For A Relative Quantification Of Gene Rearrangements, Gene Amplifications And Micro Gene Deletions". BMC Biotechnology 3.1 (2003): 18. Web. 5 Jan. 2017.
Popa, Olivia et al. INTRODUCTION TO SNP GENOTYPING BY REAL-TIME PCR. 1st ed. ROMANIA: Travaux du Muséum National d’Histoire Naturelle
“Grigore Antipa”. 2009:LII:515-522
41 Sambrook J, Fritsch EF, and Maniatis T. 2001. Molecular Cloning. Cold Spring Harbor Press. Texas: University of Texas South Western Medical Centre. p:
47.
Treatment of tuberculosis guidelines – 4th ed. World Health Organization. Geneva:
WHO. 2010.
Vuilleumier N, Rossier M, Chiappe A, Degoumois F, Dayer P, Mermillod B et al.
CYP2E1 genotype and isoniazid-induced hepatotoxicity in patients treated for latent tuberculosis. European Journal of Clinical Pharmacology.
2006;62(6):423-429.
Yuliwulandari R, Sachrowardi Q, Nishida N, Takasu M, Batubara L, Susmiarsih T et al. Polymorphisms of promoter and coding regions of the arylamine N- acetyltransferase 2 (NAT2) gene in the Indonesian population: proposal for a new nomenclature. Journal of Human Genetics. 2007;53(3):201-209.
Yuliwulandari, R. et al. "Polymorphisms Of HLA Genes In Western Javanese (Indonesia): Close Affinities To Southeast Asian Populations". Tissue Antigens 73.1 (2009): 46-53. Web. 5 Mar. 2017.
Yuliwulandari, Rika et al. "NAT2 Variants Are Associated With Drug-Induced Liver Injury Caused By Anti-Tuberculosis Drugs In Indonesian Patients With Tuberculosis". Journal of Human Genetics 61.6 (2016): 533-537.
42 ANGGARAN PENELITIAN
Material Satuan Kuantitas Harga Satuan
(Rp) Total
Buffer AL Isolasi DNA (216 mL)
per mL 28 11.500 322.000
96 Plate PCR perplate 2 25.000 50.000
Scaling Plate perlembar 2 25.000 50.000
Taqman Assay per sampel 69 32.000 2.208.000
Mastermix per sampel 69 5.250 362.350
TOTAL 2.992.250
43 BIODATA PENELITI
Nama : Rian Nurdiansyah
NIM : 1102013249
Tempat/tanggal lahir : Cirebon, 8 Juni 1995 Jenis Kelamin : Laki - Laki
Fakultas/program studi : Kedokteran umum
E-mail : rnnurdiansyah3@gmail.com
Nomor Telepon / HP : 085691469484
Alamat rumah :Jl. Transad 2 no 15 rt02/08 Jatiranggon Jatisampurna Ujung aspal Bekasi Riwayat Pendidikan : TK Walisongo 1999-2001
SDIT Al – Ishmah 2001 - 2007
Mts N 22 Jakarta 2007 - 2010 SMAN 67 Jakarta 2010 - 2013
S1 Fakultas Kedokteran Umum Universitas YARSI 2013 – Sekarang