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of diagnoses With Underlying Disease Bystander Other AOM LRTI Croup URI FWLS Supplemental Figure 2-B SUPPLEMENTAL FIGURE 2 A and B

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HCoV-NL63 HCoV-OC43 PIV Picornavirus RSV

No. of diagnoses

Without Underlying Disease

Bystander Other AOM LRTI Croup URI FWLS

0 10 20 30 40 50

HCoV-NL63 HCoV-OC43 PIV Picornavirus RSV

No. of diagnoses

With Underlying Disease

Bystander Other AOM LRTI Croup URI FWLS

Supplemental Figure 2-B

SUPPLEMENTAL FIGURE 2 A and B. Clinical diagnoses associated with single respiratory virus infections according to age (Supplemental Figure 2A) and presence or absence of underlying disease (Supplemental Figure 2B). “Other” clinical diagnoses

include acute gastroenteritis (n=5), cellulitis or cervical lymphadenitis (n=3), non-specific viral illness (n=2), seizure or other neurologic problems (n=3), apnea with bradycardia (n=1), and Kawasaki disease (n=1). AOM indicates acute otitis media; LRTIs,

lower respiratory tract infections; URI, upper respiratory tract infection; FWLS, fever without localizing signs; HCoV, human coronavirus; PIV, parainfluenza virus; RSV, respiratory syncytial virus.

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