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Supplemental Digital Content 1. Detailed search query for all included databases.

Topic Chordoma – Resection and radiotherapy

Reference Manager Covidence

Timeline

Restrictions or Limitations Key Articles

Databases PubMed, Embase, Cochrane, Scopus, Web of

Science, and ClinicalTrials.gov.

Date Run July 8, 2021

Total Number of Results 2979

Number of Duplicates Removed Remaining Number of Results

Search Prepared By Stella M. Seal, MLS

PubMed

Search number

Query Results

4 #1 AND #2 AND #3 574

3 "Radiotherapy"[Mesh] OR "radiotherapy" [Subheading] OR radiotherap* [tw]

OR radiat* [tw] OR "radio-therap*" [tw] OR "sterotactic" [tw] OR "proton beam" [tw] OR "carbon ion" [tw] OR "particle therap*" [tw] OR "hypo fractionation" [tw] OR "hypo fractionated" [tw] OR "radiation therapy" OR radiaton* [tw] OR "carbon ion" OR hadron [tw] OR proton [tw] OR "proton therapy" OR "carbon ion therapy" OR "hadron therapy" OR "charged ion"

985,464

2 chordoma [mesh] OR chordoma* [tw] OR chordoma [all fields] OR chordomas [all fields] OR chondosarcoma* [tw]

4,920 1 resect* [tw] OR "en bloc" [tw] OR "gross-total" [tw] 382,766

Embase

No. Query Results

#4 #1 AND #2 AND #3 947

#3 'en bloc resection'/exp OR 'gross total resection'/exp OR resect*:ti,ab,kw OR 'en bloc':ti,ab,kw OR 'gross total':ti,ab,kw

559628

#2 'radiotherapy'/exp OR radiotherap*:ti,ab,kw OR radiat*:ti,ab,kw OR 'radio- therap*':ti,ab,kw OR 'stereotactic':ti,ab,kw OR 'proton beam':ti,ab,kw OR 'particle therap*':ti,ab,kw OR 'hypo fractionation':ti,ab,kw OR 'hypo

fractionated':ti,ab,kw OR 'radiation therapy':ti,ab,kw OR radiaton*:ti,ab,kw OR 'carbon ion':ti,ab,kw OR hadron:ti,ab,kw OR proton:ti,ab,kw OR 'proton

therapy':ti,ab,kw OR 'carbon ion therapy':ti,ab,kw OR 'hadron therapy':ti,ab,kw OR 'charged ion':ti,ab,kw

113099 9

(2)

#1 'chordoma'/exp OR 'chordoma' OR chordoma*:ti,ab,kw OR chondosarcoma*:ti,ab,kw

7296

Cochrane

Search Name: Resection and Radiotherapy in Chordoma Date Run: 08/07/2021 21:22:30

Comment:

ID Search Hits

#1 MeSH descriptor: [Chordoma] explode all trees 15

#2 chordoma* OR chondosarcoma* 60

#3 #1 or #2 60

#4 resect* OR "en bloc" OR "gross total" 29876

#5 MeSH descriptor: [Radiotherapy] explode all trees 6290

#6 radiotherap* OR radiat* OR "radio-therap*" OR "sterotactic" OR "proton beam"

OR "carbon ion" OR "particle therap*" OR "hypo fractionation" OR "hypo fractionated" OR "radiation therapy" OR radiaton* OR "carbon ion" OR hadron OR proton OR "proton therapy" OR "carbon ion therapy" OR "hadron therapy"

OR "charged ion"

56981

#7 #5 or #6 57302

#8 #3 AND #4 AND #7 13

Web of Science

((ALL=(chordoma* OR chondosarcoma*)) AND

ALL=(resect* OR "en bloc" OR "gross total")) AND

ALL=(radiotherap* OR radiat* OR "radio-therap*" OR "stereotactic" OR "proton beam" OR "carbon ion"

OR "particle therap*" OR "hypo fractionation" OR "hypo fractionated" OR "radiation therapy" OR radiaton* OR "carbon ion" OR hadron OR proton OR "proton therapy" OR "carbon ion therapy" OR

"hadron therapy" OR "charged ion") Web of Science Core Collection Searched 7/8/21

679 references

Scopus

TITLE-ABS-KEY (chordoma* OR chondosarcoma*) AND

(3)

TITLE-ABS-KEY (resect* OR "en bloc" OR "gross total") AND

TITLE-ABS-KEY (radiotherap* OR radiat* OR "radio-therap*" OR "stereotactic" OR "proton beam" OR

"carbon ion" OR "particle therap*" OR "hypo fractionation" OR "hypo fractionated" OR "radiation therapy" OR radiaton* OR "carbon ion" OR hadron OR proton OR "proton therapy" OR "carbon ion therapy" OR "hadron therapy" OR "charged ion")

Searched 7/8/21 753 references

Clinicaltrials.gov

26 Studies found for: radiotherapy | chordoma Searched 7/8/21

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