Supplementary digital content for article:
Factors associated with Rebound Hyperthermia after Targeted Temperature Management in out-of-hospital cardiac arrest patients: an explorative sub-study of the TTH48 trial
Aki Holm, Hans Kirkegaard, Fabio Silvio Taccone, Eldar Søreide, Anders M Grejs, Valdo Toome, Christian Hassager, Bodil S Rasmussen, Timo Laitio, Christian Storm, Johanna Hästbacka, Markus B Skrifvars
Corresponding author:
MD, PhD, EDIC, FCICM, professor Markus B Skrifvars
Department of Emergency Care and Services, University of Helsinki and Helsinki University Hospital, Finland
[email protected] +358504272424
Supplementary figure and table legends:
Supplementary figure 1. Patient inclusion flowchart. RH = rebound hyperthermia.
Supplementary figure 2. Patients exceeding temperature thresholds after rewarming. CPC = cerebral performance category.
Supplementary figure 3. Patients below temperature thresholds after rewarmimng. CPC = cerebral performance category.
Figure 4 Loess smoother scatterplot of CRP (mean value line) from CA for RH patients. CA = cardiac arrest, CRP = C-reactive protein, RH = rebound hyperthermia.
Figure 5. Loess smoother scatterplot of CRP (mean value line) from CA for no RH patients. CA
= cardiac arrest, CRP = C-reactive protein, RH = rebound hyperthermia.
Supplementary figure 6. Loess smoother scatterplot of CRP (mean line) by hours from CA for patients with RH and CPC 1-2 at 6 months. CA = cardiac arrest, CPC = cerebral performance category, CRP = C-reactive protein, RH = rebound hypothermia.
Supplementary figure 7. Loess smoother scatterplot of CRP (mean line) by hours from CA for patients with no RH and CPC 1–2 at 6 months. CA = cardiac arrest, CPC = cerebral
performance category, CRP = C-reactive protein, RH = rebound hypothermia.
Supplementary figure 8. Loess smoother scatterplot of CRP (mean line) by hours from CA for patients with RH and CPC 3-5 at 6 months. CA = cardiac arrest, CPC = cerebral performance category, CRP = C-reactive protein, RH = rebound hypothermia.
Supplementary figure 9. Loess smoother scatterplot of CRP (mean line) by hours from CA for patients with no RH and CPC 3-5 at 6 months. CA = cardiac arrest, CPC = cerebral
performance category, CRP = C-reactive protein, RH = rebound hypothermia.
Supplementary table 1. Demographic characteristics and resuscitation factors Supplementary table 2. ICU parameters
Supplementary table 3. Threshold comparison results for first 72 h after rewarming end Supplementary table 4. Time and area over threshold comparison within first 72 after end of rewarmimng
