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The following content was supplied by the authors as supporting material and has not been copy-edited or verified by JBJS.

Appendix

Appendix I: Example search strategy.

Table 1: Example search strategy run on the Medline database from 1946-August 1

st

, 2019.

# Searches

1 platelet rich plasma.mp 2 placebo.mp

3 leukocyte.mp 4 hyaluronic acid.mp 5 knee osteoarthritis.mp 6 2 or 3 or 4

7 1 and 6 and 5

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C

OPYRIGHT

©

BY

T

HE

J

OURNAL OF

B

ONE AND

J

OINT

S

URGERY

, I

NCORPORATED

A

BBAS ET AL

.

T

HE

E

FFECT OF

L

EUKOCYTE

C

ONCENTRATION ON

P

LATELET

-R

ICH

P

LASMA

I

NJECTIONS FOR

K

NEE

O

STEOARTHRITIS

. A N

ETWORK

M

ETA

- A

NALYSIS

http://dx.doi.org/10.2106/JBJS.20.02258 Page 2

Appendix II: Nodesplit analysis.

Figure 1: WOMAC consistency results for 6 months follow-up using nodesplit analysis.

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Figure 2: WOMAC pain consistency results for 6 months follow-up using nodesplit analysis.

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C

OPYRIGHT

©

BY

T

HE

J

OURNAL OF

B

ONE AND

J

OINT

S

URGERY

, I

NCORPORATED

A

BBAS ET AL

.

T

HE

E

FFECT OF

L

EUKOCYTE

C

ONCENTRATION ON

P

LATELET

-R

ICH

P

LASMA

I

NJECTIONS FOR

K

NEE

O

STEOARTHRITIS

. A N

ETWORK

M

ETA

- A

NALYSIS

http://dx.doi.org/10.2106/JBJS.20.02258 Page 4

Figure 3: IKDC consistency results for 6 months follow-up using nodesplit analysis.

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