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Prevalence, awareness and control of hypertension in elderly and very elderly in Poland - results of a cross-sectional representative survey.

Short title: Hypertension in elderly in Poland

Correspondence Author:

Prof. Tomasz Zdrojewski, MD, PhD

Medical University in Gdansk, Department of Preventive Medicine and Education, ul. Dębinki 7, 80-211 Gdansk, Poland

Tel./Fax: +48 58 349 25 38; e-mail: [email protected]

Supplemental materials

Words counts: 1016, Number of tables: 2, references: 5.

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Baseline characteristics - supplementation

Current smoking was reported almost three times more often by men than by women [19.4% (95% CI: 17.7–21.3) vs. 6.7% (95% CI: 5.8–7.6), respectively], similar to past smoking [52.3% (95% CI: 50.0–54.6) vs. 17.5% (95% CI: 16.2–18.9), respectively]. Esti- mated mean body mass index (BMI) in the Polish population aged 65+ was 29.6±5.5 kg/m2 in women vs. 28.1±4.6 kg/m2 in men (P <0.001), and waist circumference (WC) was 97.3±13.6 cm vs. 102.3±13.2 cm (P <0.001), respectively. Obesity, defined as BMI ≥30.0 kg/m2, was observed in 43.0% (95%CI: 41.2–44.9) of women and 31.7% (95%CI: 29.6–

33.9) of men. The corresponding rates of visceral obesity, defined as WC ≥80 cm in women and ≥94 cm in men, were: 91.3% (95%CI: 90.3–92.3) and 76.9% (95% CI: 74.9–

78.7), respectively. Using the earlier definition of visceral obesity of WC ≥88 cm for women and ≥102 cm for men, the prevalence rates were 77.8% (95%CI: 76.2–79.2) for women and 51.3% (95%CI: 49.0–53.6) for men. Hypercholesterolemia, defined as total cholesterol ≥190 mg/dl or lipid-lowering therapy, was present in 85.3% of women (95%CI:

83.9–86.6) and in 74.9% of men (95%CI:72.7–77.0). Awareness of diabetes or/and using glucose lowering therapy were recognized in 20.8% (95%CI: 19.4–22.3) of women and 17.1% (95%CI: 15.4–18.8) of men.

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Table S1.

Prevalence of hypertension in the PolSenior survey adopted the 150 and/or 90 mmHg as diagnostic criteria.

Women Men

n % [95% CI] % [95% CI]

Hypertension 4950

65–69 yrs 781 71.9 67.2 - 76.2 68.5 63.5 - 73.2

70-74 yrs 921 79.1 74.9 - 82.7 71.5 67.2 - 75.5

75-79 yrs 842 79.1 74.7 - 82.9 61.6 56.8 - 66.1

80–84 yrs 788 75.6 70.8 - 79.8 62.5 57.7 - 67.1

85-89 yrs 863 72.3 67.5 - 76.6 55.5 50.9 - 60.1

≥ 90 yrs 755 62.2 57.2 - 67.1 51.2 46 - 56.4

Isolated

Systolic Hypertension 4634

65–69 yrs 751 4.6 2.8 - 7.3 9.2 6.5 - 12.8

70-74 yrs 871 6.0 4.0 - 8.9 13.6 10.7 - 17.2

75-79 yrs 780 10.6 7.7 - 14.3 16.3 12.9 - 20.3

80–84 yrs 740 11.8 8.7 - 15.8 15.5 12.2 - 19.5

85-89 yrs 799 14.6 11.2 - 18.8 15.2 12.0 - 18.9

≥ 90 yrs 693 14.0 10.6 - 18.1 15.6 12.0 - 20.0

Data not weighted, presented as percentage [95% confidence interval];

Hypertension defined as antihypertensive treatment or BP ≥150 and/or 90 mmHg;

Isolated Systolic Hypertension defined as systolic BP ≥150 and diastolic BP <90 mmHg during each of two visits.

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Table S2.

Population-based studies on hypertension epidemiology with available data for individuals aged 80 years and older – review of last decade.

Country Acronym

Reference position

Period Population Sample No. of

respondents

Age (years)

Oldest age-cat-

egory

The oldest age-category Prevalence

(%)

Control

(%)

Poland PolSenior - 2007-2010 national random sample 4950 ≥ 65 ≥ 90 63% 36%

UK, England HSE [1] 2011 national representative 4466 ≥ ≥ 80 80%

not available

USA NHANES [2] 1999-2004 national representative 3810 ≥ 65 ≥ 85 78% 45%

USA NHANES [3] 2005-2010 national representative 1048 ≥ 80 77% 51%

Israel

Jerusalem Longitudinal Study

[4] 2005-2006 regional

representative sample born in the years 1920-1921

1159 85 85 90%♯? 38%

USA Framingham

Heart Study [5] 1990-1999 national

original cohort (1948-52) and offspring cohort (1971-73) reexamined in 2- and 4-year intervals, respectively

5296 (14 458 person-

examinations)

≥ 60 ≥ 80 74% 40%

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the continuation of Table 5.

Latin Amer- ica, India, China

10/66 DRG [6] 2003-2009 national representative

17 014 (approximately 2000 per coun-

try)

≥ 65 ≥ 80

36% in rural India to 82%

in urban China*

not available

France Three City

Study [7] 1999-2001 regional random sample 9090 ≥ 65 ≥ 80 not

available

not available

Japan - [8] 1999-2004 regional 5 rural towns 1 256 ≥ 70 ≥ 80 76% 27%

Hypertension defined primarily or calculated as BP ≥140 and/or 90 mmHg.

Hypertension control among treated if BP <140/90 mmHg.

estimated based on available data

* standardized prevalence for age, sex and education

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References

1. Falaschetti E, Mindell J, Knott C, Poulter N. Hypertension management in England: a serial cross-sectional study from 1994 to 2011. Lancet 2014; 383: 1912-1919.

2. McDonald M, Hertz RP, Unger AN, Lustik MB. Prevalence, awareness, and management of hypertension, dyslipidemia, and diabetes among United States adults aged 65 and older. J Gerontol A Biol Sci Med Sci 2009; 64: 256-263.

3. Bromfield SG, Bowling CB, Tanner RM, Peralta CA, Odden MC, Oparil S, et al. Trends in hy- pertension prevalence, awareness, treatment, and control among US adults 80 years and older, 1988-2010. J Clin Hypertens (Greenwich ) 2014; 16: 270-276.

4. Jacobs JM, Stessman J, Ein-Mor E, Bursztyn M. Hypertension and 5-year mortality among 85-year-olds: the Jerusalem Longitudinal Study. J Am Med Dir Assoc 2012; 13: 759 e1-6.

5. Lloyd-Jones DM, Evans JC, Levy D. Hypertension in adults across the age spectrum: current outcomes and control in the community. JAMA 2005; 294: 466-472.

6. Prince MJ, Ebrahim S, Acosta D, Ferri CP, Guerra M, Huang Y, et al. Hypertension preva- lence, awareness, treatment and control among older people in Latin America, India and China: a 10/66 cross-sectional population-based survey. J Hypertens 2012; 30: 177-187.

7. Brindel P, Hanon O, Dartigues JF, Ritchie K, Lacombe JM, Ducimetiere P, et al. Prevalence, awareness, treatment, and control of hypertension in the elderly: the Three City study. J Hy- pertens 2006; 24: 51-58.

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8. Ishine M, Okumiya K, Hirosaki M, Sakamoto R, Fujisawa M, Hotta N, et al. Prevalence of hy- pertension and its awareness, treatment, and satisfactory control through treatment in elderly Japanese. J Am Geriatr Soc 2008; 56: 374-375.

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