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Table S1. Laboratory data of patients with synthetic cathinone or methamphetamine

intoxication.

Synthetic cathinone (n = 24)

Methamphetamine (n =

48) p

WBC, μL 9760 [8295, 14580] 9175 [7770, 11160] 0.207

Seg, % 71.6 [67.0, 81.1] 65.8 [57.1, 73.8] 0.003**

Lym, % 20.1 [11.5, 24.6] 25.8 [19.8, 33.8] 0.003**

Hb, % 14.5 [13.5, 15.7] 14.8 [13.9, 15.8] 0.573

PLT, per 1000 uL 263.0 [244.5, 340.5] 291.5 [256.0, 333.0] 0.528

BUN, mg/dL 10.0 [9.0, 12.0] 10.0 [9.0, 13.0] 0.699

Cr, mg/dL 1.00 [0.84, 1.19] 0.92 [0.82, 1.04] 0.245

ALT, U/L 18.0 [12.5, 34.0] 23.5 [15.0, 40.0] 0.232

AST, U/L 27.0 [19.5, 47.5] 26.0 [19.0, 41.0] 0.995

T.BIL, mg/dL 1.00 [0.60, 1.40] 0.60 [0.40, 0.90] 0.005**

Na, mEq/L 140.5 [139.0, 142.0] 140.0 [138.5, 142.0] 0.618

K, mEq/L 3.60 [3.55, 3.80] 3.70 [3.50, 4.00] 0.192

CPK, U/L 272.0 [158.0, 1348.0] 239.0 [142.0, 377.0] 0.217

Glu, mg/dL 98.0 [93.0, 108.0] 101.0 [93.0, 109.0] 0.542

Notes. Abbreviations: WBC, white blood cells; Seg, segment; Lym, lymphocytes; Hb,

hemoglobin; PLT, platelets; BUN, blood urea nitrogen; Cr, creatinine; ALT, alanine aminotransferase; AST, aspartate aminotransferase; T.BIL, total bilirubin; Na, sodium; K, potassium; CPK, creatine-phosphokinase; Glu, glucose.

Data are presented as median [25th percentile, 75th percentile].

*p < 0.05.

**p < 0.01.

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Table S2. Laboratory data of patients who required or did not require hospitalization.

Hospitalized (n = 24) Non-hospitalized (n = 48) p

WBC, μL 8555 [7940, 9905] 9525 [8090, 11980] 0.125

Seg, % 65.9 [57.1, 73.7] 68.3 [63.4, 75.5] 0.166

Lym, % 24.4 [18.6, 34.4] 22.1 [15.3, 28.2] 0.160

Hb, % 14.5 [13.1, 15.7] 14.9 [13.8, 15.8] 0.414

PLT, per 1000 uL 265.0 [231.5, 317.0] 287.0 [256.0, 346.0] 0.064

BUN, mg/dL 10.0 [9.0, 12.5] 10.0 [9.0, 13.0] 0.985

Cr, mg/dL 0.88 [0.81, 1.14] 0.93 [0.85, 1.07] 0.634

ALT, U/L 18.0 [12.5, 34.5] 24.0 [15.0, 40.0] 0.295

AST, U/L 23.5 [17.5, 42.5] 27.5 [20.0, 41.0] 0.194

T.BIL, mg/dL 0.65 [0.50, 1.00] 0.70 [0.50, 1.10] 0.435

Na, mEq/L 141.0 [139.5, 142.5] 140.0 [138.5, 142.0] 0.113

K, mEq/L 3.70 [3.60, 3.95] 3.65 [3.50, 3.85] 0.501

CPK, U/L 186.0 [148.0, 372.0] 273.0 [145.0, 972.5] 0.209

Glu, mg/dL 103.5 [92.5, 119.5] 100.5 [93.0, 108.0] 0.354

Notes. Abbreviations: WBC, white blood cells; Seg, segment; Lym, lymphocytes; Hb,

hemoglobin; PLT, platelets; BUN, blood urea nitrogen; Cr, creatinine; ALT, alanine aminotransferase; AST, aspartate aminotransferase; T.BIL, total bilirubin; Na, sodium; K, potassium; CPK, creatine-phosphokinase; Glu, glucose.

Data are presented as median [25th percentile, 75th percentile].

*p < 0.05.

**p < 0.01.

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Table S3. Laboratory data of patients with or without physical complications related to

stimulant intoxication.

With physical complication (n = 15)

Without physical complication

(n = 57) p

WBC, μL 10960 [8160, 16260] 9190 [7910, 10760] 0.095

Seg, % 71.7 [67.2, 82.6] 66.5 [57.3, 74.6] 0.053

Lym, % 21.0 [11.3, 24.1] 24.7 [17.4, 32.4] 0.049

Hb, % 14.7 [13.2, 15.7] 14.8 [13.7, 15.8] 0.626

PLT, per 1000 uL 305.0 [261.0, 356.0] 280.0 [253.0, 330.0] 0.161

BUN, mg/dL 11.0 [10.0, 16.0] 10.0 [8.0, 12.0] 0.014*

Cr, mg/dL 1.11 [0.85, 1.41] 0.90 [0.82, 1.04] 0.042

ALT, U/L 18.0 [12.0, 52.0] 22.0 [14.0, 37.0] 0.926

AST, U/L 25.0 [19.0, 72.0] 27.0 [19.0, 41.0] 0.606

T.BIL, mg/dL 0.70 [0.50, 1.40] 0.70 [0.45, 1.00] 0.241

Na, mEq/L 140.0 [139.0, 144.0] 140.0 [139.0, 142.0] 0.649

K, mEq/L 3.80 [3.60, 3.90] 3.70 [3.50, 3.90] 0.367

CPK, U/L 421.0 [158.0, 2471.0] 239.0 [143.0, 446.0] 0.118

Glu, mg/dL 103.5 [91.0, 128.0] 100.5 [93.0, 108.5] 0.479

Notes. Abbreviations: WBC, white blood cells; Seg, segment; Lym, lymphocytes; Hb,

hemoglobin; PLT, platelets; BUN, blood urea nitrogen; Cr, creatinine; ALT, alanine aminotransferase; AST, aspartate aminotransferase; T.BIL, total bilirubin; Na, sodium; K, potassium; CPK, creatine-phosphokinase; Glu, glucose.

Data are presented as median [25th percentile, 75th percentile].

*p < 0.05.

**p < 0.01.

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