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Regression equations (mixed models, independent variables of interest for hypotheses are marked in bold):

Equations set 1:

SLEEPQUAtij = γ000 + γ001*PATj + γ002*OXYj + γ010*SEXij + γ020*AGEij + γ100*DAYtij + γ200*VALLAGtij

+ r0ij + u00j + etij

SLEEPQUAtij = γ000 + γ001*PATj + γ002*OXYj + γ010*SEXij + γ020*AGEij + γ100*DAYtij + γ200*CLOSELAGtij + r0ij + u00j + etij

VALLAG and CLOSELAG have been centered around the person mean, AGE has been centered around the group mean

Equations table 2:

SLEEPQUAtij = γ000 + γ001*PATj + γ002*OXYj + γ010*SEXij + γ020*AGEij + γ030*VALPMij + γ100*DAYtij + γ200*VALDMtij + r0ij + r2ij *VALDMtij+ u00j + etij

SLEEPQUAtij = γ000 + γ001*PATj + γ002*OXYj + γ010*SEXij + γ020*AGEij + γ030*VALPMij + γ040*OXYXVALPMij + γ100*DAYtij + γ200*VALDMti + r0ij + r2ij *VALDMtij+ u00j + etij

VALPM and AGE have been centered around the group mean, VALDM has been centered around the person mean

Equations table 3:

SLEEPQUAtij = γ000 + γ001*PATj + γ002*OXYj + γ010*SEXij + γ020*AGEij + γ030*CLOSEPMij + γ100*DAYtij + γ200*CLOSEDMtij + r0ij + r2ij *CLOSEDMtij+ u00j + etij

SLEEPQUAtij = γ000 + γ001*PATj + γ002*OXYj + γ010*SEXij + γ020*AGEij + γ030*CLOSEPMij + γ040*OXYXCLOSEij + γ100*DAYtij + γ200*CLOSEDMtij + r0ij + r2ij *CLOSEDMtij+ u00j + etij

CLOSEPM and AGE have been centered around the group mean, CLOSEDM has been centered around the person mean

Equations for interaction effect with male sex:

SLEEPQUAtij = γ000 + γ001*PATj + γ002*OXYj + γ010*SEXij + γ020*AGEij + γ030*VALPMij + γ040*MANXVALij + γ100*DAYtij + γ200*VALDMtij + r0ij + r2ij *VALDMtij+ u00j + etij

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SLEEPQUAtij = γ000 + γ001*PATj + γ002*OXYj + γ010*SEXij + γ020*AGEij + γ030*CLOSEPMij + γ040*MANXCLOSEij + γ100*DAYtij + γ200*CLOSEDMtij + r0ij + r2ij *CLOSEDMtij+ u00j + etij

VALPM, CLOSEPM and AGE have been centered around the group mean, VALDM and CLOSEDM have been centered around the person mean

Equations for table 4:

SLEEPQUAti = β10*WDAYti + β20*HDAYti + β30*FEMALEti + β31*PATi*FEMALEti +

β32*OXYi*FEMALEti + β33*WVALCBi*FEMALEti + β34*WAGEi*FEMALEti + β40*MALEti + β41*PATi*MALEti + β42*OXYi*MALEti + β43*HVALCBi*MALEti + β44*HAGEi*MALEti + β50*HVALCWti + β60*WVALCWti + r5i*HVALCWti + r6i*WVALCWti + eti

SLEEPQUAti = β10*WDAYti + β20*HDAYti + β30*FEMALEti + β31*PATi*FEMALEti + β32*OXYi*FEMALEti + β33*WVALCBi*FEMALEti + β34*WVALCBXOTi*FEMALEti + β35*WAGEi*FEMALEti + β40*MALEti + β41*PATi*MALEti + β42*OXYi*MALEti +

β43*HVALCBi*MALEti + β44*HVALCBXOTi*MALEti + β45*HAGEi*MALEti + β50*HVALCWti + β60*WVALCWti + r5i*HVALCWti + r6i*WVALCWti + eti

Equations for table 5:

SLEEPQUAti = β10*WDAYti + β20*HDAYti + β30*FEMALEti + β31*PATi*FEMALEti +

β32*OXYi*FEMALEti + β33*WCLOSECBi*FEMALEti + β34*WCLOSECBXOTi*FEMALEti + β35*WAGEi*FEMALEti + β40*MALEti + β41*PATi*MALEti + β42*OXYi*MALEti +

β43*HCLOSECBi*MALEti + β44*HCLOSECBXOTi*MALEti + β45*HAGEi*MALEti + β50*HCLOSECWti

+ β60*WCLOSECWti + r5i*HCLOSECWti + r6i*WCLOSECWti + eti

SLEEPQUAti = β10*WDAYti + β20*HDAYti + β30*FEMALEti + β31*PATi*FEMALEti +

β32*OXYi*FEMALEti + β33*WCLOSECBi*FEMALEti + β34*WCLOSECBXOTi*FEMALEti + β35*WAGEi*FEMALEti + β40*MALEti + β41*PATi*MALEti + β42*OXYi*MALEti +

β43*HCLOSECBi*MALEti + β44*HCLOSECBXOTi*MALEti + β45*HAGEi*MALEti + β50*HCLOSECWti + β60*WCLOSECWti + r5i*HCLOSECWti + r6i*WCLOSECWti + eti

Legend:

γ = intercept term

u = level 3 random error term r = level 2 random error term e = level 1 residual error term

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SLEEPQUA = sleep quality

PAT = partnership appreciation task (yes=1, no=0) OXY = substance (oxytocin=1, placebo=0) SEX = sex (male = 0, female = 1)

AGE = age

DAY = day of assessment VAL = valence of interaction CLOSE = felt closeness

VALLAG = valence of interaction (daily mean) from day before CLOSELAG = felt closeness (daily mean) from day before VALPM = valence of interaction person mean

VALDM = valence of interaction daily mean

OXYXVALPM = interaction term substance*valence of interaction (person mean) CLOSEPM = felt closeness person mean

CLOSDM = felt closeness daily mean

OXYXCLOSE = interaction term substance*felt closeness (person mean)

MANXVAL = interaction term male sex (yes=1, no=0)*valence of interaction (person mean) MANXCLOSE = interaction term male sex (yes=1, no=0)*felt closeness (person mean) MALE = male sex (yes=1, no=0)

FEMALE = female sex (yes=1, no=0) Prefix „W“ = variable refers to women Prefix „H“ = variable refers to men

Suffix „CB“ = person mean centered around the group mean (centered between) Suffix „CW“ = daily mean centered around the person mean (centered within) Suffix „XOT“ = interaction term with substance

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Table S1. Comparison of coefficients from the 3 level models with those of the 2 level distinguishable dyads models

3-level models 2-level distinguishable

dyads models

women men

B SE 95% confidence

interval B B

lower upper Model 1

substance 0.5 0.21 0.09 0.91 0.62 0.3

valence of interaction (between persons)

0.5 0.13 0.25 0.75 0.06a 0.53

Model 1.a

substance*valence

of interaction 0.27 0.15 -0.02 0.56 0.44 -0.09a

Model 2

substance 0.45 0.21 0.04 0.86 0.6 0.27

felt closeness 0.43 0.11 0.21 0.65 0a 0.42

Model 2.a substance*felt

closeness 0.31 0.14 0.04 0.58 0.46 0.21

Note. a = coefficient outside of 95% confidence interval

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