https://links.lww.com/SCS/B781

Table S1. Patient demographics and peri-operative characteristics

Characteristics Group 1 Group 2 p-value

Total number of patients 6 9 —

Female/Male 6/0 6/3 —

Age at surgery, median  SD (years) 21.5  18.4 19.3  5.9 — Operative time, median  SD (hours) 5.2  1.6 4.7  0.7 0.19

Length of stay, median  SD (days) 2.0  0.7 2.0  0.5 0.24

Total treatment time, median  SD (years) 2.4  1.3 6.4  4.4 0.03 * Length of follow-up, median  SD (years) 1.1  2.4 1.8  1.6 —

SD = standard deviation

Table S2. Individual patient disease characteristics and treatment

Patient no. Sex Age Condylar status

Affected side

SPECT Treatment

1 F 23 Active Right Positive High condylectomy, BSSO, LeFort I, genioplasty, 3^rd molar extraction, fat grafting

2 F 19 Active Right Positive High condylectomy, BSSO, LeFort I, genioplasty, 3^rd molar extraction, disk plication

3 F 18 Active Left Positive High condylectomy, BSSO, LeFort I, genioplasty, meniscectomy

4 F 17 Active Left Positive High condylectomy, BSSO, LeFort I, genioplasty, disk plication, fat grafting

5 F 53 Active Left Negative High condylectomy, BSSO, LeFort I, genioplasty, fat grafting

6 F 57 Active Left Borderline High condylectomy, genioplasty, arthroplasty, mandibular contouring 7 F 33 Inactive Right Negative LeFort I, BSSO, genioplasty

8 F 21 Inactive Right Negative LeFort I, BSSO, genioplasty 9 F 18 Inactive Right Negative LeFort I, BSSO, genioplasty 10 F 29 Inactive Right Borderline LeFort I, BSSO, genioplasty 11 F 19 Inactive Left Negative LeFort I, BSSO, genioplasty 12 M 17 Inactive Right Positive LeFort I, BSSO, genioplasty 13 M 22 Inactive Right Negative LeFort I, BSSO, genioplasty 14 F 14 Inactive Left Negative LeFort I, BSSO, genioplasty

15 M 18 Inactive Left Negative BSSO, genioplasty, septorhinoplasty BSSO: bilateral sagittal split osteotomy

Table S3. Post-operative outcomes

Outcome Group 1 Group 2 p-value

Facial nerve impairment, n (%) 1 (16.7) 0 0.40

Malocclusion at LFU, n (%) 0 0 —

TMJ symptoms, n (%) 0 0 —

Readmission, n (%) 1 (16.7) 1 (1.11) 0.99

Additional symmetrizing procedures, n (%) 1 (16.7) 1 (11.1) 0.99

Patient satisfaction, n (%) 6 (100) 9 (100) —

LFU, last follow-up; TMJ, temporomandibular joint

Table S4. Subjective asymmetry ratings

Patient no. Mean pre-op score Mean post-op score p-value Group 1

1 1.88 1.56 0.08

2 3.76 2.16 < 0.01 *

3 2.36 2.14 0.23

4 4.28 1.92 < 0.01*

5 2.2 2.8 <0.01 *

6 3.14 2.42 < 0.01*

Group 2

7 2.78 1.84 < 0.01*

8 3.08 2.54 < 0.01 *

9 3.68 1.86 < 0.01*

10 2.84 1.8 < 0.01*

11 3.1 2.22 < 0.01*

12 3.44 1.8 < 0.01*

13 2.96 1.46 < 0.01*

14 2.66 2.04 < 0.01*

15 2.48 3.26 < 0.01*