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Impact of Illicit Drug Use on Quality of Life in Opioid-Dependent HIV Patients

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Supplemental Digital Content 1 to manuscript:

Impact of Illicit Drug Use on Health-Related Quality of Life in Opioid Dependent Patients Undergoing HIV Treatment

Brandon Aden, MD, MPH

1,2

Allison Dunning, MS

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Bohdan Nosyk, PhD

3,4

Eve Wittenberg, PhD

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Jeremy W. Bray, PhD

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Bruce R. Schackman, PhD

1,2

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Department of Medicine, Weill Cornell Medical College, New York, NY

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Department of

Healthcare Policy and Research, Weill Cornell Medical College, New York, NY;

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British Columbia

Centre for Excellence in HIV/AIDS, Vancouver, British Columbia;

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Faculty of Health Sciences,

Simon Fraser University, Burnaby, British Columbia;

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Center for Health Decision Science,

Harvard School of Public Health, Boston, MA;

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Department of Economics, The University of

North Carolina at Greensboro, Greensboro, NC

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Table. Full Multivariate Linear Model of SF6D Scores for BHIVES Cohort

Model variable Estimate p-value

Intercept 0.738

Age 50+ ref

Age 40-49 0.002 0.82

30-39 0.027 0.08

Age <30 -0.043 0.17

Male ref

Female -0.036 <0.01

Asian/Pacific Islander/Native American ref

African American -0.070 <0.01

Caucasian -0.021 0.38

Hispanic -0.072 <0.01

Not married ref

Married 0.025 0.08

Not stably housed ref

Stably Housed 0.023 0.02

Not working ref

Working 0.067 <0.01

Not facing criminal charges and not on parole ref

Facing criminal charges or on parole -0.028 0.01

CD4 Count>350 cells/μL ref

CD4 Count ≤350 cells/μL -0.011 0.23

Not on ART ref

On ART with poor adherence 0.022 0.26

On ART with good adherence 0.082 <0.01

Not using other drugs Ref

Using other drugs‡ -0.028 0.02

Not using illicit opioids Ref

Using illicit opioids 0.000 0.98

Not in Buprenorphine treatment ref

Buprenorphine treatment 0.026 0.03

On ART with poor adherence, using illicit opioids -0.049 0.04 On ART with good adherence, using illicit opioids -0.067 <0.01

‡Includes cocaine (includes crack cocaine), barbiturates, sedative/hypnotics, amphetamines (includes methamphetamines), hallucinogens, and inhalants

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