International
Symposium on Medicinal Plant andTraditional
MedicinePREFACE
Dosr Colleagues,
Ofl bohalf of ho organizilg oommittes, y{€ tvould liks b axpr€ss our grsat homr ard ploasurB br your
attondane and your adivo parlidpaliil on Inlemational Synpcium of Moduml Phnt and Tradltbnal
Modidno fff Human Wotihr8' hoH in Tawangmangu, Jum, 4-6n, 2014, oqanized by tt sdicinal Plant and Traditionel M€ddno Roseadr end Dovelopnent Contor (MPruRDC), Natimd lnstluto of Hoalh Resoardl and Devalopmenl, Minis[y of Healur Republic ol lndonosia cdaboraling wih National Wofiing Gmup of
lndon€sia Medidnal Plant
We were honored to have eight ksynote spoakeF boh lhom lndonosia and overseas lvho an playing a ledirg role in tp lrontine of oadr les€ar$ fold. ln hb rympcium, lvo patticulady bo$sd on mediinal
plant and faditional modcino wih t(sea albeba and Equitolu, deDiro as spocific bpics. lt was a great
sucooss b prwide tre oxcellent opporbnity to disaiss horv modicinal dant ard faditional medidn€
conuihjtss tor human wethrB. Al accoptsd arlidos will be publ'shed in he pmc*ding of synpcsium afr6r
rovie[,sd by compebnl rwiarvals.
Minisfy of Hsalfi, R6puHic of lndone3ia hurgh 'Saint'fikasi Jamu' pogram dmod b prcYido scientifc
evirJence based ol Jamu offcaq and sefaty for ulilizslion in hoalh s€rykEs. ln order b suppod hat pogram'
mseadr and dovelopment of medicinal plant and Eaditioml meditinal espedally Jamu, from upsboar b
doflnsboan by collaboration among ras€ardt instihJtos, univecitios and all sbkeholders Ebsolubly noodod. ln
his sympcium, ho distirquished invited spoak8s will pr€sfit h8ir labst findings rogsrding he symposium
henp, and rw trope hat 0p parlicipanb will enthushslically disotss fE nady raised Bseardl and dhical
questions wih tr leading expeds.
Ws hope you will harn an excellent opportunity to acquir€ adyance<t kmdedge and infumation of nEdicinal dant and faditbnal medkin€ and to sfriengilhon mutial ftiendship durir{ tlo symposium.
Sincsrsly youls,
Organizing Commitlee
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I,IST OF PARTICIPANTS AND ABSTRACT'S CODE
INSTITUTION E.MAIL
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TABLE OF CONTENTS
List of Participanb and Abstrac's Code...
WELCOME REMARKS BY SECREIARY GENEML NAT ONAL WORKING GROUP OF INDONES
il
MEDICINAL PI.ANTS
ORGANIZING COMMITTEE....
SYMPOSIUM RU1ES...
SYMPOSIUM PROGMM
.,
OML PRESENTATION SCHEDULE DAY 2, JUNE sTH 2014 ...14 ...3
irhhdzorn lxii
WELCOME REDIARKS
BY SECRETARY GENEML
NATIOI{AL WORI(II{G GROUP OF II{DONESIAI{ MEDICIT{AL PINilTS .l tr. aat ln!.flrdloo.l E n o3hm m lDdoDol. Ldhlnrl Plr ,
Jum {r - .l 2011, Ttwnungu, Cotrl Jrvr, lndonodr
Ys, Ercdclry lHr ol t5.l0t
oatr R.gttlic d lddl..b, lh, t{6bh UH
Yo,
E6diE, fftib. d $rb 0$t d Enb.Dtt . R.F Uc 0l h.lond, Brg.f od{rl btlrl Dkffrelftd Goycns d C.nH Ja,a a l'a R8ut*!
[)llhgrl$.d WHO R4.u..fd,. b kiqt-
fifrUidEd fildr G(lcd l{.timC h.fra d }Ldh REsdl.jd o€Ylhg t trcH,
Dlth0ard oitcb. G'|rC f5inC Mta d Agiafhrt Ra.dl ad Drrd$rtnL faOA [rdilglidrd Tl''. R.Frf
0aKt ngan .r Dittict
tidtullrod ho S6ril9 8cd d ho NstdC TrdftE ol hdql6b lloddC PH r,fillglfi.d s9.eirE,
tltruaEd Ps,lirpet eS,
Lda n Gan0a.nan,
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Th. dgfl ro.& d 0! b.9'nhg ol h. blks b b gh,o fimb txr gtadtdo b God $si 13 d h.vr b.rl Cvsl
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h q, onr]r trd lrodyb.
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hwe ltutg fiUrrs<m b ffi h ta sFpo.im, 69€.!ly b eud !9.*.c liun Sofi l(gc,
virhJll' lnd..d 1B'6ht* irhg dte dhorbdgBtd up.rLnc..hna.yltp(an.
Irn
p,urd ol rdcon*tg lq.r r[ h TaErynl|gu, 0! dl ol tta pttft.trd a,{ Enq,r hru ddhrlira u l
good !cf|{y d f! ildl *.
f,HherirEd Pteid1
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mlfed b b. h.ld itmebdy. Ih.t nit.. a ahd b.drne. tt htflrrd(rl d ord(fid lE dt
rd b eCy hom b rled llsr tr ho d6ale,[6,r ol
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e m.dldC Crr kr dufiE rd cd|rrut co5, hat gurt nstlt a:dc id iiqdc b tr doco d
lfqril tfirr, lli! t! Hcsf b tId b tldE l)in ,.il il.nlndol $d o . urt! ol dcfrm t,
p.qlo rtt od.o.r0r,fi ad caldnl d.cfr.ncr.
DAiUfld ed'ld Ptt+trt.
otn lfi tm &vs lrrln mdc.sl Fd rnid, dr, liardl UltE !f to b. grrfld. Tr Sadl btb6ad b. dlqrt.d *u*l ob 3 d.yr t.tttlrb1ttlah Trd@l tLddtb lfmt nrrli.!'.
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tr hqldo5 fEn . d a b rbrlc[ltl h. p.q5{cutdlly. tl(lEv!., E & lEC. tEl !t lEaa.dl
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odff*{ yello or tlcrr Olrld Enffy (IICE), p..tole,ly b dEarlgc mtand ldt{dhrr. ol ,n dch
r8r rfrieb. Tho soqEtss of nsfthd dail ed Mhrd rEdidlo rBoardl
'ld d6,sloFrrrt edviuos involvliE r!..arci, dndognnt dc.lgr, prel}P., tU, ttfl&U.! h6 grorfi d hdid hdrsfy, er6
8it ico slppod stn$ be $L b coeb coqotltvo Fd6, accoFUc Uy mdol botl d(In !0caly and
intmatooly, ild sccossbh h. h6dh lrvle. &n dr hc dfi !ir8, i] b rfl I luy ldig uey h. hs tl3o d
h..tel ,n ddm mto6aly. Ld! lod( rt tE D!try. ifmD.r of oqr! m Sito d|q{n, m.ddd ptsnl r6.0utr m vsy &rd{rt M ro m CX frgilhC b eal r8w m&iab, we a,e dco aob b mesbr ho
!.dnrdogy, thgr, x,hrt lIC(63 lJs yery dor b moy! lumrtr?
thc qitt rld trc wfrgn .s?
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lrddmed*nlfinn.t?
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uo,i beilr.r.-'; ard El.f D.ltr hlm r* "hdo h Fsld !. gr..t I I th. polndJ
IrEoD0rL.l h h. ft{l coo.*doo...'. Iho.o m ho rsdo.lil rd|g8 riidl Jr6ys E g by tt
lfibncobn b.C $gq!.
hr Mriit, Bep* U.nbd eld AI EE Pl@fiE
tY. cofts3 hat h. dah dt he !&ty d sfllcscl d Jetrl 0End mcdclr) ao ![ ruy hbd.
Sbdd.d mcdchC *nb e ebo hu in ruflt r. SH..ly, d.b ol rGardr l[dutm' plof,r, prlIiffB, t!.6rdr{d.', d d 0r rrutrly hhrdo,rs rscErfflg tr. d6rr6loF E l Jm, ol e
!c.h,rd and cdr d rE d 5 be cordcb(l' Codd.,irg itoc ocd0qis, hc hhty
oal{.rl0r, RSJbtc
ot hddE e end U,lO Re.amdr,! b |rdonqer costrg ncw{tEdcl ol Jrru &S.sr call.d Jrn lltr tr€l b dbhbtDrd,ld.
To trel.nd, we *rd b h. Uhhb. o{ H.slfi lBp€chdy, slbr he edllng d Ut ryrrpo*,ll dldalt ,
bc *ilr Edy hndod 0r Jmrt{6f 'nsy
On Uo ohE hdd UE a4gorl of Etl t{ rl giradrbod he acoGlonlill
'ld tho utrzaton d Js , h od..
b m*run ttr hol$ ol poeb, nfuor [i o6b b. tlotnfii, Jfn d6ege hmq rEddrlzdon dJsn/
end lhgt!*rg tr prod.l ccculty.
Ld6rrdGootmil,
0n bGtdf d tr FoKI I{ S TO, I wqid IG b 6!9lr!s ot a0F€ddm b 0re otlfutons d rrrry
lndl,ldd md l,[dtrtm B llll !3 rpoEr&
I$o gtlaty apprlcbb l, tro tGlols dhrt dh. comnlir.
of ilPIffrDC h o.lrElg ffi] m,rEliml Sydpo.im Fdy,
Ido hope t$ !iltE iley @ni5uh b 0E
d.drymnt d ut uHon d Ucddd Balr a$ Jrn, h lndooolh.
Trwpmenp Juef,,2011
NduC Wb.ldrg Grutp ol hdo06.b tilc.Ifid PLls,
lnddr Yuim M. S.K .. M.lG.
S.crrEy Gn rc
Aff:orr12
TERiIS OF REPFEN,ENCE
I t ct(Gn(Iflo
hd ad. b d lmn as maftadrdlfy coffy *€r ls li$ Udodcel lBfl,los ,t b.!c
nnbi of dirurt drdcr. qlrd gu{., lld ffirC mmd InorLogr. lndor*r ldl
mddr b tr rn fil d tr. horLdgr, rcOr!, *fs rd Fdkr !o!d q| !!odE, !.ts6 fll
idgm!oe.drroldfi.fi dIic. (lVlO, 2Of ).
J'Iu a m ol h.lar&r f&C nt (Ero tEl ha. b6o r6aly
'r!d t g.l.r&ns h lEltr
ranhrE a. qtlt C pit IlU! h.. b.il h.ru.d .tEfto h r!..gdl
'ld uuzlbo ol m.ddrd
Fnt a. Jsni r n6{id lro. Sda.dicadqt of Jr d!5tnd. Sdantfrcdo ol,br, a iirlty
d tio r'r proganr b p.oyida lddlc 6,id.noa o( Jilr, dllcsq ild aably br rdizddl h hiltr
tntoa.
Hom|hn Uo(hf,r{ty itd qlt d a rC I Sdldicdd|
0aJ.m, b poldC cnC.ry! b] ohirg tp
Jxrl r rr hon@d hd h i! 0$r co,:lty. Iha acffi, I! idla,r ird hirtC H^dy en yrry
irh.Uirg b hdr O. petv!. prulIltys, p,r'r.rtIo dld qrdvr tb. ol Jfiu h cunnrr*U
Fglcdon. Pol(ru^s TO a tb0il.c ffb,thg Grotr ol h.lond il.ddrC Plri btr ooErffi.r
cdlttlle 0f llcdr rnd dadopmll h.{t !m. aod d rnr 4laiioo cota.rdoo
ornbpm
aand r,|uzel d nraafdtd Cilt
Poru NAS TO h6 !r. ostr .gno b orynU! od.ba.fv. trrirr Mc. s yr. h hb ,Er, 201't,
E2PZfOOI (Ilr Crrr! ol tloddEl nd tld Tra(frqd l ddE RE dr
'td D.vrlonT.n .r) b
aoAohd r [r.oqri ol a€n rnE rerC $rpq,,, a ftffit l lffirc: hfrr'ft tx,'dld
,t&irc b hnat adrr. Tt{r rynTqtln b b tire bedli Hre creit h t! fdd ol Bnrd
plduc! dm.s8l rur$lhrffit rn kllCobd prtt .{i,a br $dnda uflu&.r dm.(Hrc
pbnl rld dind nrddr tr h. {utriul b.n ff ol hnrity rd,ap5 (bvdo@il dtr drtl6&
Ill. rodd htb h f$! lllll9odm m tr. cryb.&i, wven, dts*o itd &v*C.mi d
Esrrdr', ee Rd. u Vrdr lld Llr.r qrO.or (tor.l Pit.
rtArcnl
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1. &. t{ffii ltroi SpA IPH (tlldh ffnur, lnddrb]
Fdq (lr faerdin of Trdb.rl M.dcir h t&brd tldr Cr!
2. Pro{. t}. (}E) Ihl{an bfn (Srb Orir.d ErtrFir. fffi., hdonab)
Stngalile ol ifr.!!y ol S orm.d Ent Fa. GUIIN) dl lnddrd TrdtcC lld.h (fff)
DadoFlra,r PLnry 8F.dr
l. D. mnd,lf tmllmF'trr (i,tlo R.gulffin b hdo.r..h)
Pffitdlg Traerd llrddr b, tE Cqrru,ity d Hdh Cs $ltbm
Z Ditcb, Ga.d ol .liod h.fra d lldr Mrb RErdr rld thr,tSfn il flnfiy d
Halh, hdm.d.
Eyildrr 8...d Jrn br tLilr S6,i:a $!bm h hdanc.b
3. 0hscb.Gfi..do(fuo.d ffi,bd^giq/atr! Rr!.dt lld oadqrt tl froyolAgiqnl!,
f.aon da
B'8ak mtlgh Ptogsn b Srmort Srr*nalfy ol ffi U.dcid Ph
1. 0r. AnduL. ch,hpttu (Dertn nl ol Trfrod llGddr,Inffi)
Fd.irg lnagrdcr llli Trdlird tlcth. h ltCb Sndcr
5. M. Clren(Hads*,,*a(tuccrdrsb0lBdrycdq thhr,Cyxmnafeh.Vl@F)
A.in rc.d R!..idt h Dalrloo.rEf d Uadcia Errt rtd Elo(lYlrtly Cilan do.'l
l*or.13
6. t)r. dr. Tduo, M.Sc (Naliond lnstt te of Hedfi Reseadr ad Devdopnrng
Evolulion ol lndonc$a Tradiliml Medicine
7. Dr. dr. Sii6flanb (Na0ond lnsdtub of Hoalh Rosoardl.nd Devdopmon0
Oinid Reseadr m Traditinal and Curplonenbry lhdijne
8. tlgtysr lti lhu Humg, PhD (Reseadr Centor of Girseng and MedUnal tilatriab, Ho Ctri Minh City
l{Nlimal ln3litrb of irodi:inal Msbri*, M6h.m)
Iho Milosbne d yEh8m Giusong Rosoard| srd oe\roloFnont
9. GP JenU The Che[engE of Toditbnat iledldne tn Cilobd iia]keb
10. Dr. Sei.Rpng Oh ([XrEcbr of tlat]ral iladi*re Resoadt C6nfB (lGl€8n R6s6s.rh l.rst[tb m
Biotogy anO Sioffigy)
Pwrofiical Rdo in Modiinal Plant Sbn&dzation .l1.
I)r. k. Pasril Wahid, M.S., APU. fiho C€ofB ol Phnbtio.r Resoardl and DorotoprEnt, Mlr*sty d
Aghilttr, lndonqria) Resaldl Revim d L* (W nlpl L.l
Crlllbr hp.r Toplc.
'1. Ehnomodlcineandehnoy'urmaology
2. Medunalplgll qilhalitn and omanatim
3. Pod harEsl bdrmlogy, quatty @nbd & msrkoting of ffil poducb
1. li4deia bblogy & bkmdmology of nodidml planb
5. Phybdernisty of mod&al *nB
6. Phsrnamlogy ar{ dini).l st dy of mfikirC plant and fad.tbnal nedicine
II. PURPOSES
The pupose of Uis synrpcitm b b lmplwe ho rde d Janu in lrod$ ard to sdfgrro lndmosiil
hoaltfiy podo. nis syrryc*m b dmod:
L b illuwe he uuiza0on of Jam nd$/o*ing in lndone$a
2. b imgwa ho inb6t d Jemu ulilizalbn by cfimunity and medicd 8bfi
U. OAIEATDYEXUE
0.b : June 446r,20lrl
Phc. : Aldiluium of Ih. Confo of ModHnd pbnt and Tradlilnal tlodidp Rolaardl ad
Development L*u Sfeet No. ,l0, Tewengmauu, Karangryar, Solo.
V. PARNCPAf,fB
Tho elpocbd padidpants a,!:
l. Acad6fi*)s, rosoidle s and studfib in ho field of hElh, pttemacy, agridlturo,and bblogy
2. Profsasimab: rnodicd docbrs, pnarmaUef, nursss, lEdtr anaF, nuh,tof*rts, n*Or;vei, neafi Fad[dat
3. hBtt dofis lllabd b irdusfy d Jrni, fadiiiond modhino, and pturnaoeutcat Th€ p€ddpilB d be diyidod inb trflo catogorios:
l. P.ss6nbr parlidpanb (ord and posior)
2. Rogular pedkipsnb
u. oRcr,iltzER
Its rynpoeim b organiz0d by Modidl8l Plant 8nd Traditk nal irodijne Rssoardl and Darolop,nont
C€nte (MPruRDC), Natind lnstit b ot H€dh R6sdl and Devdopnrern Ministy of H6altr Ropnub d lndoneeh
it#:ore 14
ORGANIZING COMMITTEE
Director Advlsory
Project Director
Steering Committe
Organizing Committee
Chaiman
Vice*halrman
Secretariale
Treasurer
SclentMc Board Coordinator
Publication, Coordinator
Promotlon,
Agenda and Coordinator
and
Minister of Health
Director General of National lnstitute of Health Researdr and
Development
General Secreatary of Working Group of lndonesia Medicinal Plant Director of Medicinal Plant and Traditional Medicine Research and Development Centre
Prof. Dr. dr. Agus Punradianto, SH., M.Si., Sp.F(K) DR.dr. Trihono, M.Sc. (NIHRD)
Prot Suwijiyo Pramono, DEA., Apt Prof. L. Broto S. Kardono
Prof. DR. Amri Bachtiar Prof. DR. Gemini Alam dr. Noor W'rjayahadi
Nagiot Cansalony Tambunan, SKM., ME dr. Oanang Ardiyanto
Tri Widayat, M. Sc
lndah Laksmiwati, S.Sos Ema Wahyuningsih, SS Saitul Danang, SS
Ristiyanti Punraningsih, SE Heri Dwi Prasetiyo, SE
Dyah Perwitasari, SE.
Wahyu Joko Priambodo, S.Si Drs. Slamet Wahyono
Nita Supriyati, M. Biotech Rohmat Mujahid, M.Sc Dyah Subositi, M. Sc dr Agus Triyono
dr Sunu Pamadyo Fauzi, MP
Heru sudrajat, MP
Rahma Widyastuti, SP drh. Galuh Ralnawati Nurul Husniati L, SP
dr. Peristiwan Ridha Widhi Astana
Documentation
Harto Widodo, M.Biotech.
Prasetyo Hermanto, S.Kom Pedro Harmoko, S.Sos
Kristoforus lvan Pramudya W, Si.Kom lr Yuli Widiyastuti MP
Sari Haryanti, M.Sc
Nuning Rahmawati, M. Sc Amalia Damayanti, M. Si Meeting
intnhlzorn 15
dr. Zuraida Zulkamain M.B. Samil Adi, M.Si
ElokVVtdayanti, M,Si Fitriana, S.Farm
Saryanto, S.Si., M
Endang Brotoioyo,Attd
tealand Eeverage
Coordinator Toif Setieni, fud
Sugeng Wnarsih Equipment, accomodaff on, and Tnnsportatbn
Cdordinator : Akhmad Saikhu, M.ScPH
Edwin Fajar Setyawan, Sl(M
AgusWn&rto, STP
Exhibltim and SponoonhiP
Coordinabr
Agus Efierdy, ST
Sanrvoro Kamino Rusmanto
Esa Aii Pratama, S.E.
Nongah Ratd, Arnd
AsdWuryani, Amd
Bagas NurMi, Amd
ul5
region. Amidiol, inophyllum-c, inophyllum€, oleanolic
fu
ranodienone, ocoteine, pronuciferine and enadoline have EGFR and can be developed as new anticancer agent.
acid, inophyllolide chromanol, chitranone, polential anticancer aclivity by inhibiting human
Ksywords: lndonesia herbal database, docking, in silico, anticancer, Epidermal Growth Fac{or Receptor
0.MPP-015
DEIERMINATION OF ANTIOXIDAT{T ACTIVITY USING DPPH UETHOD TO THE ETHYL ACETATE FRACTION OF VELVEI APPLE(Diospyros Drencoi A. Dc.) LEAF IIIETHANOL EXTRACT
Yulio l{ur Aii Surya and Yohanes Dwiatnaka'
Faculty of Pharmacy, Sanah Dharma University, lndonesia 'Conesponding aufior: [email protected]
Free radicals activity causes cells damage and promotes degenerative diseases. Flavonoid is a phenolic
compound known as natural antioxidant. Velvet apple (Dbspfos Dlancli A. DC.) plant has high mntent of phenolic compound. This research was aimed to determine he total phenolic content and antioidani ac{ivity from ethyl acetate fra6{ion of mohanol extract of velvet apple's leaf. Determination ol total phenolic content
as gallic acid equivalent was determined using the Folin4iocalteu method. The antioxidant actvity was
determined using oPPH (l ,1{iphenyl-2-picrylhydrazy') mehod. The anlioxidant activity was shted as 1C50.
The result showed hat the ohyl acetate ftaction of methanolic extrac't of velvet apgle's loaf contained total phenolic of 933.5t6.62 mg/g (as gallic acid equivalent) and uE lC50 was 13.9t0.25 mcg/mL.
Koywords: antioxidanl, Diospyns blancoi A. 0C., ethyl acetate fraction, DPPH, total phenolic contenl
o-MPP416
STABILITY CHARACTERIZAIION OF FCAROTET{E FRO ATBON BAI{ANA lllusa paradlslaca srprentum) PEEL: ITS POTENCY AS VITAIflN A SUPPLEiIENT
Suparmf', Harta Prasetyalr, llartar o l{artosupond and Lasmono Trl Sunaryantd
rMedical Faqllty, Sultan Agung lslamic University, Semarang, lndonesia zsemarang Eye Center Sultan Agung lslamic Hospilal, Semerang, lndonesia 3Master Program of Biology Satya wacana Christian Unive6ity. Salaliga, lndonesia
'Agrioltural Faqrlty Satya Wacana Christian University, Salatiga, lndonesia
'Corssponding author: supami@unissula ac.id
Exploration eflorts of Fcarotene pigment from Ambon banana luusa pandisiaca sapisnlum ) peel as a
natural source of vitamin A, became one of the altemative solutions to overcome he problems ol vitamin A capsules supplying in lndonesia. However, he use ol his pigments in vitamin A supplement products may face some problems due to ib stability during storage. The characterizalion of Fcamtene on temperaturs,
pH, light, and oxidator-reductor was investigated to determine ib stability.The spectE absorplion was analyzed by UV-Vis spectroscopy. The stability of p - carotene crude extract from yellow banana peel compaEd wit! Fcarotene mafter E-Merck. Crude extracl and p{afoteno was more slable at low
temperature (4 'C )to roorn temperature (27 'C). Crude exllact relatively rnore stable at high temPrature
(50'C) compared wilh Fcarotene. Crude extract Fcarotene was more stable in dark storage conditions
.Polychromatic light inadiation for 3 hours per half hour had caused degradation of 2.4 % and 1.9 %; for the crude extract and 0 - calotene respectively. Crude extract was more stable at pH 6 (neufal). The oxidizing and reducing agenb did not significanty influence the stability of the pigment. Fcarotene lrom yellow ambon banana peel was slable on tgmperature, pH, light, and oxidatorreductor. lt is potential as vitamin A
supplement.
Keywods:ambon banana peel, Fcarotene, light, pH, oxidator, reduc{or, stability tompelature