LEMBAR
HASIL PENILAIAN SEJAWAT SEBIDANG ATAU PEER REVIEW KARYA ILMIAH : JURNAL ILMIAH
Judul Jurnal Ilmiah (Artikel) : Synthesis of Colloidal Silver Nanoparticles in Various Liquid Media Using Pulse Laser Ablation Method and Its Antibacterial Properties
Nama/ Jumlah Penulis : 3 Orang
Status Pengusul : Penulis pertama/ Penulis ke 3 / Penulis Korespondesi **
Identitas Jurnal Ilmiah : a. Nama Jurnal : Indonesian Journal of Chemistry b. Nomor ISSN : 1411-9420
c. Vol, No., Bln Thn : Vol 21, June 2021 d. Penerbit : Gadjah Mada University e. DOI artikel (jika ada) : 10.22146/ijc.60344
f. Alamat web jurnal : https://jurnal.ugm.ac.id/ijc/index
Alamat Artikel : https://journal.ugm.ac.id/ijc/article/view/60344
g. Terindex : Scopus
Kategori Publikasi Jurnal Ilmiah : √ Jurnal Ilmiah Internasional/Internasional Bereputasi (beri pada kategori yang tepat) Jurnal Ilmiah Nasional Terakreditasi
Jurnal Ilmiah Nasional Tidak Terakreditasi
Hasil Penilaian Peer Review :
Komponen Yang Dinilai
Nilai Maksimal Jurnal Ilmiah
Nilai Akhir Yang Diperoleh Internasional
Nasional Terakreditasi
Nasional Tidak Terakreditasi
a. Kelengkapan unsur isi jurnal (10%) 4 3
b. Ruang lingkup dan kedalaman pembahasan (30%)
12 12
c. Kecukupan dan kemutahiran
data/informasi dan metodologi (30%)
12 12
d. Kelengkapan unsur dan kualitas terbitan/jurnal (30%)
12 10
Total = (100%) 40 37
Nilai Pengusul = 40% x 37 = 14,8 Catatan Penilaian artikel oleh Reviewer :
1. Kesesuaian dan kelengkapan unsur isi jurnal:
Kesesuaian dan kelengkapan unsur jurnal sudah sesuai Guide of Author pada Indonesian Journal of Chemistry, Experimental Section, Result and Analysis, Conclussion, Acknowledgement, References). Substansi publikasi sesuai dengan bidang ilmu penulis yaitu fisika laser yang mempunyai keterkaitan antar bagian (skor=3,00)
2. Ruang lingkup dan kedalaman pembahasan:
Makalah sudah sesuai dengan ruang lingkup jurnal yaitu all areas of chemistry, including educational chemistry, applied chemistry, dan chemical engineering. Topik makaalah yang ditulis sesuai dengan kajian lingkup jurnal tersebut.
Pembahsaan sangat komprehensif dan sangat baik yang membandingkan dengan penelitian lain (12 dari 30 referensi) (skor=12,00)
3. Kecukupan dan kemutakhiran data/informasi dan metodologi:
Hasil penelitian cukup memberikan informasi pada bidang fisika laser yang disertai metodologi yang cukup baik untuk mencapai hasil yang diharapkan. Referensi sejumlah 30 buah dengan 19 referensi dibawah 10 tahun dan 11 referensi diatas 10 tahun serta medukung topik yang dibahas (skor = 12,00)
4. Kelengkapan unsur dan kualitas terbitan:
Indonesian Journal of Chemistry termasuk dalam kategori Jurnal Internasional Bereputasi dengan editorial board lebih dari empat negara dan kontributor lebih dari 4 negara, ISSN: 1411-9420 terindeks scopus dengan SJR=0,273 (2020)/Q3 dan proses review jurnal bagus (skor=10,00)
Semarang, 4 Maret 2022 Reviewer 1
Prof. Dr. Kusworo Adi, S.Si., M.T.
NIP. 197203171998021001 Unit Kerja : Fisika
Bidang Ilmu: Fisika
√
LEMBAR
HASIL PENILAIAN SEJAWAT SEBIDANG ATAU PEER REVIEW KARYA ILMIAH : JURNAL ILMIAH
Judul Jurnal Ilmiah (Artikel) : Synthesis of Colloidal Silver Nanoparticles in Various Liquid Media Using Pulse Laser Ablation Method and Its Antibacterial Properties
Nama/ Jumlah Penulis : 3 Orang
Status Pengusul : Penulis pertama/ Penulis ke 3 / Penulis Korespondesi **
Identitas Jurnal Ilmiah : a. Nama Jurnal : Indonesian Journal of Chemistry b. Nomor ISSN : 1411-9420
c. Vol, No., Bln Thn : Vol 21, June 2021 d. Penerbit : Gadjah Mada University e. DOI artikel (jika ada) : 10.22146/ijc.60344
f. Alamat web jurnal : https://jurnal.ugm.ac.id/ijc/index
Alamat Artikel : https://journal.ugm.ac.id/ijc/article/view/60344
g. Terindex : Scopus
Kategori Publikasi Jurnal Ilmiah : √ Jurnal Ilmiah Internasional/Internasional Bereputasi (beri pada kategori yang tepat) Jurnal Ilmiah Nasional Terakreditasi
Jurnal Ilmiah Nasional Tidak Terakreditasi
Hasil Penilaian Peer Review :
Komponen Yang Dinilai
Nilai Maksimal Jurnal Ilmiah
Nilai Akhir Yang Diperoleh Internasional
Nasional Terakreditasi
Nasional Tidak Terakreditasi
a. Kelengkapan unsur isi jurnal (10%) 4 3,9
b. Ruang lingkup dan kedalaman pembahasan (30%)
12 11,8
c. Kecukupan dan kemutahiran
data/informasi dan metodologi (30%)
12 11,8
d. Kelengkapan unsur dan kualitas terbitan/jurnal (30%)
12 11,9
Total = (100%) 40 39,4
Nilai Pengusul = 40% x 39,4 = 15,76 Catatan Penilaian artikel oleh Reviewer :
1. Kesesuaian dan kelengkapan unsur isi jurnal:
Sangat sesuai dan lengkap mulai dari abstrak, pendahuluan, prosedur eksperimen, hasil dan pembahasan, sampai pada kesimpulan dan dafar pustaka yang digunakan.
2. Ruang lingkup dan kedalaman pembahasan:
Paper ini membahas tentang sintesis nanopartikel perak (AgNPs) sebagai agen antibakteri dalam produk konsumen, kosmetik, dan industri makanan, dalam berbagai media polivinilpirolidon (PVP), polietilen glikol (PEG), dan kitosan menggunakan metode sintesis ablasi laser pulsa.
3. Kecukupan dan kemutakhiran data/informasi dan metodologi:
Data-data hasil yang diperoleh dalam penelitian mutakhir dengan didukung metodologi yang tepat.
4. Kelengkapan unsur dan kualitas terbitan:
Karya ini diterbitkan dalam jurnal berkualitas Q3 dengan SJR 0,27 oleh Gadjah Mada University dengan unsur-unsur yang lengkap serta kualitas yang baik.
Semarang, 05 Maret 2022 Reviewer 2
Dr. Eng. Eko Hidayanto, S.Si., M.Si.
NIP. 197301031998021001 Unit Kerja : Fisika
Bidang Ilmu: Fakultas Sains dan Matematika
√
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Indonesian Journal of Chemistry
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Synthesis of colloidal silver nanoparticles in various liquid media using pulse laser ablation method and its antibacterial properties
Avicenna S., Nurhasanah I., Khumaeni A.
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Department of Physics, Faculty of Science and Mathematics, Diponegoro University, Jl. Prof. Soedarto SH, Tembalang, Semarang, 50275, Indonesia
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Abstract
The silver nanoparticles (AgNPs) have been applied as an antibacterial agent in consumer products, cosmetics, and food industries. In this present work, AgNPs were synthesized in various mediums of polyvinylpyrrolidone (PVP), polyethylene glycol (PEG), and chitosan using the pulse laser ablation synthesis method. Experimentally, a pulse Nd:YAG laser beam (1064 nm, 7 ns, 30 mJ) was directed using a silver mirror and focused using a quartz lens with a focal length of 30 mm on a silver metal plate placed in a petri dish containing liquid mediums for 120 min to produce colloidal silver nanoparticles. The results certified that All AgNPs have a spherical shape with polydisperse size in all media, including PVP, PEG, and chitosan. The smallest AgNPs have been produced in PVP medium with an averaged smallest size of 11.62 nm. Based on this result, PVP is the preferred medium to produce AgNPs with the smallest size and good stability. The produced silver nanoparticles have been successfully employed as an antibacterial agent, which is experimentally demonstrated by using Escherichia coli and Staphylococcus aureus. The result certified that the produced silver nanoparticles
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Chitosan; Liquid media of PVP; Nd:YAG laser; PEG; Pulse laser ablation technique; Silver nanoparticles
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References (30)
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Toxicity of Silver Nanomaterials in Higher Eukaryotes
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Silver nanoparticles as a medical device in healthcare settings:
A five-step approach for candidate screening of coating agents
Cited 60 times http://rsos.royalsocietypublishing.org/content/5/1/171113.full.pdf
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Multifunctional WS &M-AgNPs superhydrophobic conductive sponges for application in various sensors
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3/3/22, 8:07 PM Editorial Team
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Home > About the Journal > Editorial Team
Editorial Team
Editor-in-Chief
Nuryono Nuryono, Laboratory of Inorganic Chemistry, Department of Chemistry, Universitas Gadjah Mada, Indonesia
Managing Editor
Indriana Kartini, Laboratory of Inorganic Chemistry, Department of Chemistry, Universitas Gadjah Mada, Indonesia
Editorial Board
Dr. Fajar Inggit Pambudi, Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Gadjah Mada, Indonesia, Indonesia
Dr. Stalis Norma Ethica, Universitas Muhammadiyah Semarang, Indonesia Dr. Wahyu Dita Saputri, National Research and Innovation Agency, Indonesia
Tau k Abdillah Natsir, Departemen Kimia, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Gadjah Mada (UGM), Sekip utara Bulaksumur, Yogyakarta, 55281, Indonesia
Dr. Maulidan Firdaus, Department of Chemistry, Universitas Sebelas Maret, Indonesia
Niko Prasetyo, Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Gadjah Mada, Indonesia Robby Noor Cahyono
Dr. Tran Anh Vy, Department of Chemical and Biochemical Engineering, Gachon University, Korea, Republic of
Dr. Mahmood Ahmed, Department of Chemistry, Division of Science and Technology, University of Education, College Road, Lahore- Pakistan, Pakistan
Dr. Charles Edwin Raja Gabriel, University of Notre Dame, Notre Dame, Indiana, United States
Assoc. Prof. Dr. Roswanira Abdul Wahab, Department of Chemistry, Universiti Teknologi Malaysia, Malaysia Mudasir Mudasir, Laboratory of Analytical Chemistry, Department of Chemistry, Universitas Gadjah Mada, Indonesia Prof. Hideaki Hisamoto, Department of Applied Chemistry, Osaka Prefecture University, Japan
Prof. Joe da Costa, Department of Chemical Engineering, University of Queensland, Australia Dr. Maurizio Barbieri , Department of Earth Science, Sapienza University, Italy
Ming Cai, Tongji University, China
Muhammad Idham Darussalam Mardjan, Laboratory of Organic Chemistry, Department of Chemistry, Universitas Gadjah Mada, Indonesia Prof. Pornthep Sompornpisut, Department of Chemistry, Chulalongkorn University, Thailand
Prof. Dr. Taghreed Hashim Al-Noor, Ibn-Al-Haitham Education College /University of Baghdad, Iraq
Assoc. Prof. Dr. Praveen Kumar Sharma, Department of Chemistry, Lovely Professional University, Punjab, India
Dr. Saprizal Hadisaputra, Chemistry Education Division, Faculty of Science and Education, University of Mataram, Indonesia Dr. Satya Candra Wibawa Sakti, Laboratory of Inorganic Chemistry, Department of Chemistry, Universitas Airlangga, Indonesia Dr. Winifred Uduak Anake, Department of Chemistry, College of Science and Technology, Covenant University, Nigeria Aulia Sukma Hutama, Laboratory of Physical Chemistry, Department of Chemistry, Universitas Gadjah Mada, Indonesia Dr. Adhi Dwi Hatmanto, Universitas Gadjah Mada, Indonesia
Administration Support
Djoko Prihandono, Department of Chemistry, Universitas Gadjah Mada, Indonesia
Iqmal Tahir, Laboratory of Physical Chemistry, Department of Chemistry, Universitas Gadjah Mada, Indonesia
Aulia Ratri Hapsari, Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Gadjah Mada, Indonesia
Indonesian Journal of Chemistry (ISSN 1411-9420 / 2460-1578) - Chemistry Department, Universitas Gadjah Mada, Indonesia.
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Home > Archives > Vol 21, No 3 (2021)
Vol 21, No 3 (2021)
Accredited by RISTEK-BRIN No.: 85/M/KPT/2020 (April 1, 2020)
Table of Contents
Articles
Enhancement of Cobalt Concentration Supported on Mesoporous Silica towards the Characteristics and Activities of Catalysts for the Conversion of Waste Coconut Oil into Gasoline and Diesel Oil
Wega Trisunaryanti, Triyono Triyono, Nugroho Raka Santoso, Savitri Larasati, Cahyarani Paramesti, Dyah Ayu Fatmawati
10.22146/ijc.55633 Abstract views : 1967 | views : 1639
527-536
In uence of Calcination Temperature on Size, Morphology and Optical Properties of ZNO/C Composite Synthesized by a Colloidal Method
Siham Lhimr, Saidati Bouhlassa, Bouchaib Ammary
10.22146/ijc.56309 Abstract views : 2023 | views : 1040
537-545
Phytochemical Analysis of Bioactive Extracts and Seed Oil of Three Euphorbia Species from Algerian Flora by LC-MS and GC-MS
Nadia Toudert, Farida Zakkad, Noureddine Dadda, Abdelouaheb Djilani, Amadou Dicko, Salah Eddine Djilani
10.22146/ijc.56679 Abstract views : 1200 | views : 909
546-553
Equilibrium Modeling of Astaxanthin Extraction from Haematococcus pluvialis
Putri Restu Dewati, Rochmadi Rochmadi, Abdul Rohman, Avido Yuliestyan, Arief Budiman 10.22146/ijc.56965 Abstract views : 1359 | views : 891
554-563
Synthesis of Cu2+ Doped ZnO by the Combination of Sol-Gel-Sonochemical Methods with Duck Egg Albumen as Additive for Photocatalytic Degradation of Methyl Orange
Sherly Kasuma Warda Ningsih, Hary Sanjaya, Bahrizal Bahrizal, Edi Nasra, Syuhada Yurnas 10.22146/ijc.57077 Abstract views : 1122 | views : 1147
564-574
Synthesis, Antiproliferative and Antimalarial Activities of Dinuclear Silver(I) Complexes with Triphenylphosphine and Thiosemicarbazones Ligands
Nur Adila Fatin Mohd Khir, Mohd Ridzuan Mohd Abdul Razak, Fariza Juliana Nordin, Nur Rahimah Fitrah Mohd Sofyan Nur Fadilah Rajab Rozie Sarip
575-587
Home About Login Register Search Current Archives Announcements Statistics Indexing & Abstracting Journal History Contact
3/3/22, 8:08 PM Vol 21, No 3 (2021)
https://jurnal.ugm.ac.id/ijc/issue/view/4577 2/3
KEYWORDS
HPLCQSARTiO2
adsorption
antioxidantbiodieselcatalyst characterization
chitosan
eugenolextractionheavy metals immobilizationkinetics methylene blue molecular docking photocatalyst silica synthesis transesteri cation zeolite
Indones. J. Chem.
indexed by:
CURRENT ISSUE Fitrah Mohd Sofyan, Nur Fadilah Rajab, Rozie Sarip
10.22146/ijc.57343 Abstract views : 1213 | views : 688 | views : 145
Deposition of Hydroxyapatite on Silica Made from Rice Husk Ash to Produce the Powder Component of Calcium Phosphate Cement
Tri Windarti, Widjijono Widjijono, Nuryono Nuryono 10.22146/ijc.57900 Abstract views : 2701 | views : 1509
588-597
Polarity Effect on the Electronic Structure of Molybdenum Dichalcogenides MoXY (X, Y = S, Se): A Computational Study Based on Density-Functional Theory
Salsabila Amanda Putri, Edi Suharyadi, Moh. Adhib Ulil Absor 10.22146/ijc.57949 Abstract views : 1305 | views : 987
598-608
Groundwater Recharge Area Based on Hydrochemical and Environmental Isotopes Analysis in the South Bandung Volcanic Area
Rizka Maria, Satrio Satrio, Teuku Yan Waliyana Muda Iskandarsyah, Bombom Rachmat Suganda, Robert Mohammad Delinom, Dyah Marganingrum, Wahyu Purwoko, Dady Sukmayadi, Hendarmawan Hendarmawan
10.22146/ijc.58633 Abstract views : 1473 | views : 1055
609-625
Morphology of NdFeB-Type Permanent Magnet Coercivity Enhancement by Heat Treatment Process Eva Afrilinda, Dagus Resmana Djuanda, Shinta Virdhian, Martin Doloksaribu, Moch Iqbal Zaelana Muttahar, Sri Bimo Pratomo
10.22146/ijc.59096 Abstract views : 1383 | views : 1005
626-634
Hierarchical Structure of Magnetic Nanoparticles -Fe3O4- Ferro uids Revealed by Small Angle X-Ray Scattering
Gea Fitria, Arum Patriati, Mujamilah Mujamilah, Maria Christina Prihatiningsih, Edy Giri Rachman Putra, Siriwat Soontaranon
10.22146/ijc.59114 Abstract views : 832 | views : 737
635-643
Modeling and Thermodynamic Values of Complex Equilibrium of Cobalt(II) with Diethylenetriaminepentaacetic Acid in Aqueous Solution
Ghusoon Faidhi Hameed, Fawzi Yahya Wadday, Nahla Shakir Salman 10.22146/ijc.59169 Abstract views : 1565 | views : 1009
644-650
Analysis and Characterization of Solid and Liquid Organic Fertilizer from Hydrothermal Carbonization (HTC) of Chicken Feather and Blood Waste
Agus Kuncaka, Rizky Ibnufaatih Arvianto, Almas Sha ra Ramadhanty Bunga Latifa, Munawir Ramadhan Rambe, Adhitasari Suratman, Sugeng Triono
10.22146/ijc.59353 Abstract views : 1234 | views : 1357
651-658
Synthesis, Characterization and Optimization of Oleyl Oleate Wax Ester Using Ionic Liquid Catalysts Naowara Al-Ara , Nadia Salih, Jumat Salimon
10.22146/ijc.59694 Abstract views : 920 | views : 761
659-668
Performance Improvements of Bixin and Metal-Bixin Complexes Sensitized Solar Cells by 1-Methyl-3- propylimidazolium Iodide in Electrolyte System
Winda Rahmalia, Septiani Septiani, Uray Amira Naselia, Thamrin Usman, Imelda Hotmarisi Silalahi, Zéphirin Mouloungui
10.22146/ijc.60633 Abstract views : 981 | views : 780
669-678
Surface Complexation of Chromium(VI) on Iron(III) Hydroxide: Mechanisms and Stability Constants of Surfaces Complexes
Mhamed Hmamou, Fatima Ezzahra Maarouf, Bouchaib Ammary, Abdelkebir Bellaouchou 10.22146/ijc.60634 Abstract views : 1028 | views : 983
679-689
Carotenoid Analysis from Commercial Banana Cultivars (Musa spp.) in Malang, East Java, Indonesia Jodiawan Jodiawan, Devi Natalia Chrisdiyanti, Nur Vi’atin, Monika Nur Utami Prihastyanti, Rosita Dwi Chandra, Heriyanto Heriyanto, Chandra Ayu Siswanti, Lia Hapsari, Tatas Hardo Panintingjati Brotosudarmo
10.22146/ijc.60865 Abstract views : 1554 | views : 822
690-698
Anticancer Activities of Chemical Constituents from Leaves and Twigs of Mitrephora winitii
Sukee Sukdee, Puttinan Meepowpan, Narong Nantasaen, Siriporn Jungsuttiwong, Sarinya Hadsadee, Wilart Pompimon
10.22146/ijc.61085 Abstract views : 1947 | views : 895
699-707
3/3/22, 8:08 PM Vol 21, No 3 (2021)
https://jurnal.ugm.ac.id/ijc/issue/view/4577 3/3
Synthesis and DFT Study of the Complexation of Schiff Base Derived Curcumin and L-Tyrosine with Al(III), Ag(I), and Pb(II) Metal Ions
Ali Mahmood Ali, Tagreed Hashim Al-Noor, Eid Abdalrazaq, Abdel Aziz Qasem Jbarah 10.22146/ijc.62188 Abstract views : 1367 | views : 662
708-724
A Theoretical Study on Vibrational Energies of Molecular Hydrogen and Its Isotopes Using a Semi-classical Approximation
Redi Kristian Pingak, Albert Zicko Johannes, Fidelis Nitti, Meksianis Zadrak Ndii 10.22146/ijc.63294 Abstract views : 1706 | views : 1631
725-739
A Green Method for Synthesis of Silver-Nanoparticles-Diatomite (AgNPs-D) Composite from Pineapple (Ananas comosus) Leaf Extract
Saprini Hamdiani, Yeng-Fong Shih
10.22146/ijc.63573 Abstract views : 1604 | views : 1088
740-752
Short Communication
Data Fusion of UV-Vis and FTIR Spectra Combined with Principal Component Analysis for Distinguishing of Andrographis paniculata Extracts Based on Cultivation Ages and Solvent Extraction
Antonio Kautsar, Wulan Tri Wahyuni, Utami Dyah Sya tri, Syifa Mu ihah, Nursifa Mawadah, Eti Rohaeti, Zulhan Arif, Bambang Prajogo, Muhammad Bachri Amran, Abdul Rohman, Mohamad Ra 10.22146/ijc.60321 Abstract views : 1018 | views : 904
753-760
Synthesis of Colloidal Silver Nanoparticles in Various Liquid Media Using Pulse Laser Ablation Method and Its Antibacterial Properties
Syifa Avicenna, Iis Nurhasanah, Ali Khumaeni
10.22146/ijc.60344 Abstract views : 1171 | views : 635
761-768
Solvatochromism and Theoretical Studies of Dicyanobis(phenylpyridine)iridium(III) Complex Using Density Functional Theory
Noorshida Mohd Ali, Anthony J. H. M. Meijer, Michael D. Ward, Norlinda Daud, Norhayati Hashim, Illyas Md Isa
10.22146/ijc.62763 Abstract views : 1153 | views : 759 | views : 198
769-775
Review
Potentiality of Graphene Oxide and Polyoxometalate as Radionuclides Adsorbent to Restore the Environment after Fukushima Disaster: A Mini Review
Bangun Satrio Nugroho, Muh Nur Khoiru Wihadi, Fabian Grote, Siegfried Eigler, Satoru Nakashima 10.22146/ijc.60493 Abstract views : 2053 | views : 937
776-786
Indonesian Journal of Chemistry (ISSN 1411-9420 / 2460-1578) - Chemistry Department, Universitas Gadjah Mada, Indonesia.
View The Statistics of Indones. J. Chem.
Indones. J. Chem., 2021, 21 (3), 699 - 707
Sukee Sukdee et al.
699
Anticancer Activities of Chemical Constituents from Leaves and Twigs of Mitrephora winitii
Sukee Sukdee
1, Puttinan Meepowpan
1*, Narong Nantasaen
2, Siriporn Jungsuttiwong
3, Sarinya Hadsadee
3, and Wilart Pompimon
41
Department of Chemistry, Center of Excellence for Innovation in Chemistry (PERCH-CIC), Faculty of Science, Graduate School, Chiang Mai University, 239 Huay Kaew Road, Chiang Mai 50200, Thailand
2
The Forest Herbarium, Department of National Park, Wildlife and Plant Conservation, Ministry of Natural Resources and Environment, Bangkok, 10220, Thailand
3
Center for Organic Electronic and Alternative Energy, Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Ubon Ratchathani University, Ubon Ratchathani, 34190, Thailand
4
Laboratory of Natural Products, Faculty of Science and Center for Innovation in Chemistry, Lampang Rajabhat University, Lampang, 52100, Thailand
* Corresponding author:
tel: +668-69192120
email: [email protected] Received: November 4, 2020 Accepted: March 9, 2021 DOI: 10.22146/ijc.61085
Abstract: The genus Mitrephora has been investigated, and its anti-inflammatory, anti- bacterial, and anti-parasitical activities were examined along with its potential as an anti-cancer cell line and inhibitor for platelet aggregation. In this work, air-dried leaves and twigs of M. winitii were grounded and extracted with n-hexane, ethyl acetate, and methanol, respectively. Chromatographic separations of these extracts led to the isolation of three known compounds and one new compound (compound 2). The chemical structures of these were identified using the spectroscopic investigation of 1D- and 2D-NMR, and the resulting data confirmed these as stigmasterol (1), (3,4-dimethoxyphenyl)(5-(3,4- dimethoxyphenyl)-4-(hydroxymethyl)tetrahydrofuran-3-yl)methanol (2), diayangambin (3), and methyl-L-inositol (4). The chemical constituents were reported the first time in M. winitii. Compound 2 showed anti-cancer cell lines with ED
5013.07 µg/mL against KB cells and then was tested for cytotoxicity against MCF-7 cells with ED
5011.77 µg/mL.
Keywords: Mitrephora winitii; anticancer; extraction; extract
■ INTRODUCTION
Within the pantropical family of shrubs, trees, and lianas, the Annonaceae family comprises an interesting group of medicinal plants. Consisting of roughly 130 genera and 2,500 species, the majority of these are found in Asia, Australia, and Pacific regions [1]. One of these is the genus Mitrephora, which is comprised of some 48 species found in Asia and Australia [2]. In Thailand, 12 species are found, and some plants in this genus have been used in the country for the production of folk medicine [3]. These genera have great potential for the treatment of cancers, bacterial infections, brain dysfunctions, and hypertension [1]. Phytochemical investigations have established that Mitrephora species contain diterpenoids,
polyacetylene carboxylic acids/esters, fatty acids, lignans, sesquiterpenes, alkaloids [4-9], the diterpenoids and alkaloids have shown significant anti-microbial, anti-malarial, anti-platelet aggregation, and cytotoxic potential [10-12]. Interestingly, the M. winitii was the new source and reported on the antitumor and potent cytotoxic activities of the genus showed high activity anticancer agents.
The M. winitii [13] extracts with solvents (n-
hexane, ethyl acetate, and methanol) and isolated by
column chromatography was found to contain four
compounds. They were identified using IR, NMR, and
ESI-MS spectrometry to yield stigmasterol (1), (3,4-
dimethoxyphenyl)(5-(3,4-dimethoxyphenyl)-4-(hydroxy
Indones. J. Chem., 2021, 21 (3), 708 - 724
Ali Mahmood Ali et al.
708
Synthesis and DFT Study of the Complexation of Schiff Base
Derived Curcumin and L-Tyrosine with Al(III), Ag(I), and Pb(II) Metal Ions
Ali Mahmood Ali
1, Tagreed Hashim Al-Noor
1, Eid Abdalrazaq
2*, and Abdel Aziz Qasem Jbarah
21
Department of Chemistry, Ibn Al-Haithem College of Education for Pure Science, Baghdad University, Baghdad, Iraq
2
