LAMPIRAN
Lampiran 1 Tabel Konversi Dosis (Paget and Barnes, 1964)
Mencit 20 g
Tikus 200 g
Marmut 400 g
K elinci
1 .5 kg
Kucing 2 kg
Kera 4 kg
Anjing 12 kg
Manusia 70 kg
Mencit 20 g
1 ,0
7 ,0
1 2,29
2 7,8
2 8,7
6 4,1
1 24,2
3 87,9 Tikus
200 g
0 ,14
1 ,0
1 ,74
3 ,9
4 ,2
9 ,2
1 7,8
6 0,5 Marmut
400 g
0 ,08
0 ,57
1 ,0
2 ,25
2 ,4
5 ,2
1 0,2
3 1,5
Kelinci 1.5 kg
0 ,04
0 ,25
0 ,44
1 ,0
1 ,06
2 ,4
4 ,5
1 4,2 Kucing
2 kg
0 ,03
0 ,23
0 ,41
0 ,92
1 ,0
2 ,2
4 ,1
1 3,0
Kera 4 kg
0 ,016
0 ,11
0 ,19
0 ,42
0 ,45
1 ,0
1 ,9
6 ,1 Anjing
2 kg
0 ,008
0 ,06
0 ,10
0 ,22
0 ,24
0 ,52
1 ,0
3 ,1
Manusia 70 kg
0 ,0026
0 ,018
0 ,031
0 ,07
0 ,76
0 ,16
0 ,32
1 ,0
Lampiran 2 Hasil Statistik
Descriptives
Kelompok S
tatistic
S td. Error
Neutrofil K
+
Mean 1
3,1429
1 ,48690 95% Confidence
Interval for Mean
Low er Bound
9 ,5045 Upp
er Bound
1 6,7812
5% Trimmed Mean 1
3,1032
Median 1
4,0000
Variance 1
5,476
62
Std. Deviation 3
,93398
Minimum 9
,00
Maximum 1
8,00
Range 9
,00
Interquartile Range 9
,00
Skewness ,
219
, 794
Kurtosis -
1,891
1 ,587 K
-
Mean 1
3,0000
1 ,04654 95% Confidence
Interval for Mean
Low er Bound
1 0,4392 Upp
er Bound
1 5,5608
5% Trimmed Mean 1
3,0000
Median 1
3,0000
Variance 7
,667
Std. Deviation 2
,76887
Minimum 9
,00
Maximum 1
7,00
Range 8
,00
Interquartile Range 5
,00
Skewness -
,198
, 794
Kurtosis -
,557
1 ,587 P
1
Mean 8
,0000
1 ,44749 95% Confidence
Interval for Mean
Low er Bound
4 ,4581
63
Upp er Bound
1 1,5419
5% Trimmed Mean 7
,8333
Median 7
,0000
Variance 1
4,667
Std. Deviation 3
,82971
Minimum 4
,00
Maximum 1
5,00
Range 1
1,00
Interquartile Range 6
,00
Skewness ,
922
, 794
Kurtosis ,
961
1 ,587 P
2
Mean 7
,8571
1 ,71031 95% Confidence
Interval for Mean
Low er Bound
3 ,6722 Upp
er Bound
1 2,0421
5% Trimmed Mean 7
,6190
Median 6
,0000
Variance 2
0,476
Std. Deviation 4
,52506
Minimum 3
,00
Maximum 1
7,00
Range 1
4,00
Interquartile Range 4
,00
64
Skewness 1
,611
, 794
Kurtosis 3
,061
1 ,587 P
3
Mean 1
0,8571
1 ,66803 95% Confidence
Interval for Mean
Low er Bound
6 ,7756 Upp
er Bound
1 4,9387
5% Trimmed Mean 1
0,6746
Median 1
0,0000
Variance 1
9,476
Std. Deviation 4
,41318
Minimum 7
,00
Maximum 1
8,00
Range 1
1,00
Interquartile Range 9
,00
Skewness ,
980
, 794
Kurtosis -
,709
1 ,587 L
imfosit
K +
Mean 7
7,4286
1 ,99830 95% Confidence
Interval for Mean
Low er Bound
7 2,5389 Upp
er Bound
8 2,3182
5% Trimmed Mean 7
7,4762
Median 7
7,0000
Variance 2
7,952
Std. Deviation 5
,28700
65
Minimum 7
0,00
Maximum 8
4,00
Range 1
4,00
Interquartile Range 1
0,00
Skewness ,
128
, 794
Kurtosis -
1,185
1 ,587 K
-
Mean 8
9,5714
1 ,46152 95% Confidence
Interval for Mean
Low er Bound
8 5,9952 Upp
er Bound
9 3,1477
5% Trimmed Mean 8
9,4683
Median 8
9,0000
Variance 1
4,952
Std. Deviation 3
,86683
Minimum 8
5,00
Maximum 9
6,00
Range 1
1,00
Interquartile Range 7
,00
Skewness ,
649
, 794
Kurtosis -
,283
1 ,587 P
1
Mean 9
0,5714
1 ,54083 95% Confidence
Interval for Mean
Low er Bound
8 6,8012 Upp
er Bound
9 4,3417
66
5% Trimmed Mean 9
0,6349
Median 9
1,0000
Variance 1
6,619
Std. Deviation 4
,07665
Minimum 8
4,00
Maximum 9
6,00
Range 1
2,00
Interquartile Range 7
,00
Skewness -
,435
, 794
Kurtosis -
,266
1 ,587 P
2
Mean 8
3,5714
1 ,32480 95% Confidence
Interval for Mean
Low er Bound
8 0,3298 Upp
er Bound
8 6,8131
5% Trimmed Mean 8
3,6349
Median 8
4,0000
Variance 1
2,286
Std. Deviation 3
,50510
Minimum 7
8,00
Maximum 8
8,00
Range 1
0,00
Interquartile Range 6
,00
Skewness -
,345
, 794
67
Kurtosis -
,638
1 ,587 P
3
Mean 8
4,2857
2 ,14603 95% Confidence
Interval for Mean
Low er Bound
7 9,0346 Upp
er Bound
8 9,5369
5% Trimmed Mean 8
4,2619
Median 8
4,0000
Variance 3
2,238
Std. Deviation 5
,67786
Minimum 7
7,00
Maximum 9
2,00
Range 1
5,00
Interquartile Range 1
1,00
Skewness -
,041
, 794
Kurtosis -
1,524
1 ,587
Tests of Normality
K elompok
Kolmogorov-Smirnova Shapiro-Wilk
S tatistic
d f
S ig.
S tatistic
d f
S ig.
N eutrofil
K +
, 216
7 ,
200*
, 853
7 ,
131 K
-
, 214
7 ,
200*
, 959
7 ,
808 P
1
, 174
7 ,
200*
, 911
7 ,
404 P
2
, 289
7 ,
078
, 826
7 ,
074
68
P 3
, 291
7 ,
074
, 833
7 ,
085 L
imfosit
K +
, 179
7 ,
200*
, 926
7 ,
514 K
-
, 170
7 ,
200*
, 955
7 ,
777 P
1
, 159
7 ,
200*
, 979
7 ,
955 P
2
, 122
7 ,
200*
, 974
7 ,
925 P
3
, 172
7 ,
200*
, 946
7 ,
693
*. This is a lower bound of the true significance.
a. Lilliefors Significance Correction
One-Sample Kolmogorov-Smirnov Test
N eutrofil
L imfosit
N 7 7
Normal Parametersa,b
Mea n
1 3,1429
7 7,4286 Std.
Deviation
3 ,93398
5 ,28700 Most Extreme
Differences
Abso lute
, 216
, 179 Positi
ve
, 216
, 170 Nega
tive
- ,177
- ,179
Test Statistic ,
216
, 179
Asymp. Sig. (2-tailed) ,
200c,d
, 200c,d a. Test distribution is Normal.
b. Calculated from data.
c. Lilliefors Significance Correction.
d. This is a lower bound of the true significance.
One-Sample Kolmogorov-Smirnov Test
69
N eutrofil
L imfosit
N 7 7
Normal Parametersa,b
Mea n
1 3,0000
8 9,5714 Std.
Deviation
2 ,76887
3 ,86683 Most Extreme
Differences
Abso lute
, 214
, 170 Positi
ve
, 146
, 170 Nega
tive
- ,214
- ,119
Test Statistic ,
214
, 170
Asymp. Sig. (2-tailed) ,
200c,d
, 200c,d a. Test distribution is Normal.
b. Calculated from data.
c. Lilliefors Significance Correction.
d. This is a lower bound of the true significance.
One-Sample Kolmogorov-Smirnov Test
N eutrofil
L imfosit
N 7 7
Normal Parametersa,b
Mea n
8 ,0000
9 0,5714 Std.
Deviation
3 ,82971
4 ,07665 Most Extreme
Differences
Abso lute
, 174
, 159 Positi
ve
, 174
, 095 Nega
tive
- ,148
- ,159
Test Statistic ,
174
, 159
Asymp. Sig. (2-tailed) ,
200c,d
, 200c,d a. Test distribution is Normal.
70
b. Calculated from data.
c. Lilliefors Significance Correction.
d. This is a lower bound of the true significance.
One-Sample Kolmogorov-Smirnov Test
N eutrofil
L imfosit
N 7 7
Normal Parametersa,b
Mea n
7 ,8571
8 3,5714 Std.
Deviation
4 ,52506
3 ,50510 Most Extreme
Differences
Abso lute
, 289
, 122 Positi
ve
, 289
, 103 Nega
tive
- ,198
- ,122
Test Statistic ,
289
, 122
Asymp. Sig. (2-tailed) ,
078c
, 200c,d a. Test distribution is Normal.
b. Calculated from data.
c. Lilliefors Significance Correction.
d. This is a lower bound of the true significance.
One-Sample Kolmogorov-Smirnov Test
N eutrofil
L imfosit
N 7 7
Normal Parametersa,b
Mea n
1 0,8571
8 4,2857 Std.
Deviation
4 ,41318
5 ,67786 Most Extreme
Differences
Abso lute
, 291
, 172 Positi
ve
, 291
, 152
71
Nega tive
- ,191
- ,172
Test Statistic ,
291
, 172
Asymp. Sig. (2-tailed) ,
074c
, 200c,d a. Test distribution is Normal.
b. Calculated from data.
c. Lilliefors Significance Correction.
d. This is a lower bound of the true significance.
ANOVA
Sum of
Squares df
Mean
Square F
Si g.
N eutrofil
Between Groups
186,000 4 46,500 2,
990
,0 34 Within
Groups
466,571 30 15,552
Total 652,571 34
Li mfosit
Between Groups
782,457 4 195,61
4
9, 400
,0 00 Within
Groups
624,286 30 20,810
Total 1406,74
3
34
Multiple Comparisons
LSD Dependent Variable
(I) Kelompok
(J) Kelompok
Mean Difference (I-J)
S td. Error
S ig.
95% Confidence Interval
Low er Bound
Neutrofil K+ K- ,1428
6
2 ,10797
, 946
- 4,1622
P1 5,142
86*
2 ,10797
, 021
,837 8
P2 5,285
71*
2 ,10797
, 018
,980 7
P3 2,285
71
2 ,10797
, 287
- 2,0193
K- K+ -
,14286
2 ,10797
, 946
- 4,4479
72
P1 5,000
00*
2 ,10797
, 024
,695 0
P2 5,142
86*
2 ,10797
, 021
,837 8
P3 2,142
86
2 ,10797
, 317
- 2,1622
P1 K+ -
5,14286*
2 ,10797
, 021
- 9,4479
K- -
5,00000*
2 ,10797
, 024
- 9,3050
P2 ,1428
6
2 ,10797
, 946
- 4,1622
P3 -
2,85714
2 ,10797
, 185
- 7,1622
P2 K+ -
5,28571*
2 ,10797
, 018
- 9,5908
K- -
5,14286*
2 ,10797
, 021
- 9,4479
P1 -
,14286
2 ,10797
, 946
- 4,4479
P3 -
3,00000
2 ,10797
, 165
- 7,3050
P3 K+ -
2,28571
2 ,10797
, 287
- 6,5908
K- -
2,14286
2 ,10797
, 317
- 6,4479
P1 2,857
14
2 ,10797
, 185
- 1,4479
P2 3,000
00
2 ,10797
, 165
- 1,3050
Limfosit K+ K- -
12,14286*
2 ,43836
, 000
- 17,1226
P1 -
13,14286*
2 ,43836
, 000
- 18,1226
P2 -
6,14286*
2 ,43836
, 017
- 11,1226
P3 -
6,85714*
2 ,43836
, 009
- 11,8369
K- K+ 12,14
286*
2 ,43836
, 000
7,16 31
P1 -
1,00000
2 ,43836
, 685
- 5,9798
P2 6,000
00*
2 ,43836
, 020
1,02 02
73
P3 5,285
71*
2 ,43836
, 038
,305 9
P1 K+ 13,14
286*
2 ,43836
, 000
8,16 31
K- 1,000
00
2 ,43836
, 685
- 3,9798
P2 7,000
00*
2 ,43836
, 007
2,02 02
P3 6,285
71*
2 ,43836
, 015
1,30 59
P2 K+ 6,142
86*
2 ,43836
, 017
1,16 31
K- -
6,00000*
2 ,43836
, 020
- 10,9798
P1 -
7,00000*
2 ,43836
, 007
- 11,9798
P3 -
,71429
2 ,43836
, 772
- 5,6941
P3 K+ 6,857
14*
2 ,43836
, 009
1,87 74
K- -
5,28571*
2 ,43836
, 038
- 10,2655
P1 -
6,28571*
2 ,43836
, 015
- 11,2655
P2 ,7142
9
2 ,43836
, 772
- 4,2655
*. The mean difference is significant at the 0.05 level.
