Supplementary Table 1. Univariate analysis (Cox proportional HR) - all-cause
mortality: detailed results.
BMI means body mass index, DSA:
donor- specific anti-HLA
Characteristic s
Variable Label Number
of patien
ts
Number
of deaths HR 95% CI p
Recipient characteristic
s
Age (per 1-yr
increment)
415 100 1.03
1
[1.012- 1.051]
<0.00 1
Gender Male 327 74 1 -
Female 88 26 1.41 [0.90-2.22] 0.14
Weight 415 100 1 [0.98-1.01] 0.79
(per 1-kg increment)
BMI < 18.5 kg/m2 18 8 2.72 [1.28-5.75]
≥ 18.5 and < 25
kg/m2 235 47 1 -
≥ 25 and < 30
kg/m2 123 31 1.32 [0.84-2.08] 0.03
≥ 30 kg/m2 39 14 1.94 [1.07-3.53]
Past history of No 333 75 1 -
cardiac surgery Yes 82 25 1.44 [0.92-2.27] 0.13
Time since onset Yes 130 27 1 -
of HF ≤ 1 year No 274 68 1.21 [0.77-1.89] 0.38
Duration on the list
(per 1-day increment)
415 100 0.99 [0.99-
1.001] 0.69
Pre-HTx ECMO No 297 78 1 -
Yes 118 22 0.69 [0.43 - 1.11] 0.11
Long term MCS No 356 83 1 -
Yes 59 17 1.36 [0.81-2.30] 0.26
Mechanical No 402 97 1 -
ventilation Yes 13 3 0.88 [0.28-2.77] 0.82
Creatinine
clearance ≥ 90 171 25 1 -
(ml/min/1.73 m2) ≥ 60 and < 90 130 31 1.73 [1.02-2.94]
≥ 30 and < 60 104 39 2.64 [1.60-4.37] <0.00 1
< 30 or dialysis 10 5 3.83 [1.46-10.03]
Total bilirubin 387 93 1.00 [0.99-1.01] 0.92
(per 1-mmol/l increment) Donor
characteristic s
Age < 50 years 212 37 1 -
≥ 50 years 203 63 1.94 [1.30-2.92] 0.001
Sex Male 260 56 1 -
Female 155 44 1.39 [0.93-2.06] 0.10
Weight 415 100 0.99 [0.98-1.004] 0.16
(per 1-kg increment)
Cause of death Traumatic 88 23 1 -
Cerebrovascular 237 51 0.71 [0.43-1.16] 0.32
Anoxia 80 23 1.05 [0.59-1.87]
Other 10 3 1.09 [0.33-3.64]
Prior cardiac
arrest No 301 71 1
Yes 114 29 1.16 [0.76-1.79] 0.49
Transplant characteristic
s
Gender
mismatch No 315 74 1 -
Yes 100 26 1.11 [0.71-1.74] 0.65
Weight
mismatch No 375 86 1 - 0.088
Yes 40 14 1.69 [0.96-2.97]
Cold ischemia 414 99 1.39 [1.10-1.76] 0.004
(per 1-hour increment)
HLA mismatch 414 100 0.96 [0.84-1.09] 0.51
(per 1 MM increment)
Anti-HLA DSA No 238 59 1 -
at day 0 Yes 177 41 0.96 [0.64-1.42] 0.82
