SUPPLEMENTARY TABLE 3: Values of anti-glycoprotein 2 IgG antibodies against isoform 4 in patients with Crohn’s disease
Patient
Number Patient ID Serum sample Date
(dd/mm/yy )
Iso4 IgG in
U/ml not
stable stable positive or negative
stable
positive stable negative
1 MC-014 1 06/12/06 1,39
MC-014 2 29/07/08 98,84
MC-014 3 15/01/09 54,91 x
2 MC-017 1 15/12/09 22,44
MC-017 2 02/03/10 23,4
MC-017 3 31/01/11 23,47 x x
3 MC-018 1 16/05/01 17,46
MC-018 2 16/10/02 13,59
MC-018 3 16/05/07 12,57 x x
4 MC-019 1 14/08/09 39,1
MC-019 2 02/11/09 301
MC-019 3 19/07/11 53,93 x x
5 MC-020 1 25/08/04 26,98
MC-020 2 27/02/07 20,64
MC-020 3 06/05/08 32,74 x
6 MC-024 1 08/12/99 11,19
MC-024 2 21/07/06 15,66
MC-024 3 02/12/08 11,43 x x
7 MC-032 1 19/06/07 10,72
MC-032 2 04/11/10 10,18
MC-032 3 17/02/11 9,21 x x
8 MC-035 1 10/02/05 29,48
MC-035 2 07/01/08 19,89 x
9 MC-041 1 26/08/04 237,97
MC-041 2 15/11/05 208,66
MC-041 3 27/04/12 301 x x
10 MC-042 1 16/11/06 8,51
MC-042 2 08/05/07 5,47
MC-042 3 19/10/10 22,44 x x
11 MC-049 1 05/07/99 24,63
MC-049 2 08/05/00 27,83 x x
12 MC-073 1 29/12/03 10,24
MC-073 2 24/04/08 4,08 x x
13 MC-071 1 05/02/08 10,04
MC-071 2 17/06/08 7,83 x x
14 MC-078 1 08/02/06 11,19
MC-078 2 29/06/07 23,89
MC-078 3 13/03/08 19,63 x
15 MC-079 1 14/07/09 235,09
MC-079 2 22/05/12 301 x x
16 MC-081 1 06/03/08 7,33
MC-081 2 24/09/08 11,62 x x
17 MC-091 2 09/03/10 9,62
MC-091 1 24/09/09 7,82 x x
18 MC-094 1 21/10/97 5,63
MC-094 2 17/07/06 18,19 x x
19 MC-096 1 27/08/10 7,51
MC-096 2 07/12/10 7,15 x x
20 MC-098 1 24/02/06 5,16
MC-098 2 29/08/06 20,32
MC-098 3 04/08/10 12,17 x x
21 MC-102 1 04/04/13 301
MC-102 2 01/08/13 231,38 x x
22 MC-103 1 26/11/98 6,06
MC-103 2 02/12/03 9,13
MC-103 3 15/11/05 6,21 x x
23 MC-107 1 12/02/08 12,54
MC-107 2 23/02/11 14,03 x x
24 MC-111 1 27/06/03 35,72
MC-111 2 24/01/06 20,57 x
25 MC-115 1 30/11/09 30,18
MC-115 2 30/03/10 91,75
MC-115 3 18/07/12 66,01 x x
26 MC-116 1 27/09/05 29,76
MC-116 2 16/01/07 251,79
MC-116 3 23/10/06 161,96 x x
27 MC-118 1 11/04/07 7,51
MC-118 2 26/07/07 13,72
MC-118 3 04/02/10 28,04 x
28 MC-120 1 07/08/01 301
MC-120 2 20/08/03 301
MC-120 3 15/08/06 301 x x
29 MC-123 1 15/08/12 21,48
MC-123 2 18/11/13 301 x
30 MC-125 1 05/02/13 14,49
MC-125 3 03/07/13 13,69
MC-125 2 20/02/13 14,71 x x
31 MC-126 1 12/07/07 42,54
MC-126 2 30/04/08 28,56 x x
32 MC-127 1 04/02/04 12,93
MC-127 2 11/04/06 9,19
MC-127 3 29/03/07 11,96 x x
33 MC-129 1 02/07/01 26,98
MC-129 2 04/04/06 35,24 x x
34 MC-136 1 12/02/08 10,72
MC-136 2 20/05/08 10,6 x x
35 MC-141 1 25/03/03 205,92
MC-141 2 16/08/06 185,61
MC-141 3 26/06/09 160,73 x x
36 MC-143 1 18/03/02 23,22
MC-143 2 08/04/08 10,63
MC-143 3 03/02/09 35,53 x
37 MC-146 1 05/06/13 6,51
MC-146 2 07/08/13 25,85
MC-146 3 15/11/13 19,24 x
38 MC-147 1 21/02/06 2,79
MC-147 2 06/03/07 14,13
MC-147 3 24/04/08 11,83 x x
39 MC-149 1 20/10/11 17,1
MC-149 2 20/12/11 18,88
MC-149 3 15/01/13 15,81 x x
40 MC-155 1 28/08/08 26,22
MC-155 2 30/08/13 110,75 x x
41 MC-156 1 06/10/03 203,32
MC-156 2 15/11/05 43,69
MC-156 3 27/02/07 56,65 x x
42 MC-159 1 10/06/99 9,21
MC-159 2 17/05/00 6,52
MC-159 3 13/11/01 11,16 x x
43 MC-168 1 10/03/99 23,82
MC-168 2 02/08/07 22 x x
44 MC-169 1 24/07/02 72,4
MC-169 2 10/02/04 77,32 x x
45 MC-171 1 06/05/08 17,95
MC-171 2 02/02/09 20,91 x x
46 MC-172 1 19/01/00 20,06
MC-172 2 17/08/04 6,99
MC-172 3 24/05/05 12,16 x x
47 MC-176 1 10/08/04 47,91
MC-176 2 13/10/06 6,78 x
∑ 10 37 16 21
Titers of IgG antibodies against glycoprotein 2 isoform 4 in 47 patients with Crohn’s disease at 120 time-points. 37 (79%) have been stable positive or negative whereas 10 patients switched from negative to positive or vice versa.
Antibody titers below the minimum standard were defined as 1 U/ml and values above maximum were set 301 U/ml.
