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Supplementary table 1: Bivariate analysis showing associations between perception and barrier factors to guideline implementation and Nurses working with cardiovascular patients perceived knowledge of European Society of Cardiology (ESC) guidelines of participants.

Knowledge poor/average n

(%)

Knowledge good/very good/excellent

n (%)

χ2 p

The ESC guidelines are easy to use (468) Agree/ strongly agree (395) (84%) 136 (35) 259 (65)

28.45 <0.001 Disagree/ strongly disagree (73) (16%) 50 (68) 23 (32)

There are inconsistent messages from different guidelines (475)

Agree/ strongly agree (219) (46%) 101 (40%) 94 (43%)

.452 0.501 Disagree/ strongly disagree (256) (54%) 155 (60%) 125 (57%)

The ESC guidelines are good educational tools (471) Agree/ strongly agree (431) (92%) 162 (38) 269 (62)

10.34 0.001 Disagree/ strongly disagree (40) (8%) 26 (65) 14 (35)

The ESC guidelines change too often (460) Agree/ strongly agree (144) (31%) 68 (47) 76 (53)

4.68 0.030 Disagree/ strongly disagree (316) (69%) 114 (36) 202 (64)

The ESC guidelines are too long (452) Agree/ strongly agree (247) (55%) 103 (42) 144 (58)

1.775 0.183 Disagree/ strongly disagree (205) (45%) 72 (35) 133 (65)

The ESC guidelines are easy to access (470) Agree/ strongly agree (363) (77%) 128 (35) 235 (65)

14.06 <0.001 Disagree/ strongly disagree (107) (23%) 60 (56) 47 (44)

The ESC guidelines have unrealistic targets for patients to achieve (443)

Agree/ strongly agree (124) (28%) 56 (45) 68 (55)

2.356 0.125 Disagree/ strongly disagree (319) (72%) 117 (37) 202 (63)

I do not agree with some of the ESC guidelines (451) Agree/ strongly agree (87) (19%) 31 (36) 56 (64)

0.418 0.518 Disagree/ strongly disagree (364) (81%) 146 (40) 218 (60)

There is no leadership on ESC guideline implementation in my workplace (468)

Agree/ strongly agree (311) (67%) 146 (47) 165 (53)

16.87 <0.001 Disagree/ strongly disagree (157) (33%) 42 (27) 115 (73)

There are not enough resources to adequately implement and follow up the recommendations in the ESC guidelines (478)

Agree/ strongly agree (323) (68%) 151 (47) 172 (53)

10.98 0.001 Disagree/ strongly disagree (155) (32%) 47 (30) 108 (70)

There is a consistent message throughout the team Agree/ strongly agree (340) (71%) 122 (36) 218 (64) 14.71 <0.001

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that guidelines are important (481) Disagree/ strongly disagree (141) (29%) 78 (55) 63 (45) Lack of time is a major barrier to using ESC guidelines

(478)

Agree/ strongly agree (323) (68%) 152 (47) 171 (53)

18.81 <0.001 Disagree/ strongly disagree (155) (32%) 40 (26) 115 (74)

I feel I have the responsibility to use the ESC guidelines (467)

Agree/ strongly agree (392) (84%) 146 (37) 246 (63)

12.56 0.001 Disagree/ strongly disagree (75) (16%) 45 (60) 30 (40)

I understand all the detail in ESC guidelines (470) Agree/ strongly agree (223) (47%) 58 (26) 165 (74)

36.5 <0.001 Disagree/ strongly disagree (247) (53%) 133 (54) 114 (56)

I do not use ESC guidelines because my role does not specify that I should (475)

Agree/ strongly agree (114) (24%) 69 (60) 45 (40)

22.46 <0.001 Disagree/ strongly disagree (361) (76%) 126 (35) 235 (65)

I have the confidence to challenge other members of the multidisciplinary team when ESC guidelines are not implemented (469)

Agree/ strongly agree (276) (59%) 77 (28) 199 (72)

45.43 <0.001 Disagree/ strongly disagree (193) (41%) 114 (59) 79 (41)

I would need further information on ESC guideline updates (477)

Agree/ strongly agree (404) (85%) 184 (45) 222 (55)

11.67 <0.001 Disagree/ strongly disagree (73) (15%) 17 (23) 56 (77)

I would need further education to implement ESC guidelines (482)

Agree/ strongly agree (377) (78%) 183 (49) 194 (51)

30.03 <0.001 Disagree/ strongly disagree (105) (22%) 19 (18) 86 (82)

I am not in a position to influence current practices and routines that would assist the implementation of ESC guidelines (481)

Agree/ strongly agree (247) (51%) 131 (53) 116 (47)

25.47 <0.001 Disagree/ strongly disagree (234) (49%) 70 (30) 164 (70)

My workload prevents me taking on the additional task of ensuring guidelines are implemented and followed up (478)

Agree/ strongly agree (286) (60%) 137 (48) 149 (52)

12.47 <0.001 Disagree/ strongly disagree (192) (40%) 60 (31) 132 (28)

Although risk factors are monitored, usual care in my practice does not always have automatic follow up

Agree/ strongly agree (241) (50%) 107 (44) 134 (56)

1.489 0.222 Disagree/ strongly disagree (239) (50%) 92 (39) 147 (61)

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(480)

* significant level 0.05

# Fishers exact test

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