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Supplemental Digital Content

Appendix 1. Results of Generalized Linear Models Estimating Caregiving Costs: Testing Sensitivity of Model Results to Self-Employed Status (Excluding Self-Employed Caregivers)

Variable Model n Coefficient

($ amount)

SE 95% CI

(lower, upper

p

Model 1: Total Indirect Costs+ 780

TRD (1) vs No TRD (0) 0.300

(2483.11) 0.063 0.177, 0.423 .0000

Age -0.161

(-2754.16) 0.029 -0.218,

-0.105 .0000

Male -0.137

(-2030.97)

0.091 -0.315, 0.042

.1321

White 0.041

( 566.89) 0.070 -0.096,

0.178 .5582

Part-time Job -0.310

(-4352.57) 0.077 -0.461,

-0.159 .0001

Major Condition indicator 0.395

(4336.26) 0.073 0.252,

0.538 .0000 TRD No TRD Difference

Estimated indirect Cost of TRD vs.

No TRD*

9,580.32 7,097.21 2483.11 .0000

Model 2: Total Direct Costs 785

TRD (1) vs No TRD (0) 0.290

(7024.03) 0.052 0.188,

0.391 .0000

Age -0.008

(-223.38) 0.023 -0.053,

0.037 .7401

Male -0.095

(-2615.97) 0.080 -0.252,

0.062 .2378

White 0.424

(10504.19)

0.082 0.264, 0.585

.0000

Part-time Job -0.222

(-6689.52) 0.072 -0.363,

-0.080 .0022

Major Condition indicator 0.116

(3051.43) 0.055 0.008,

0.224 .0339 TRD No TRD Difference

Estimated Direct Cost of TRD vs. No

TRD* 27,940.63 20,916.60 7024.03 .0000

+ All costs are annualized and based on the United States Bureau of Labor Statistics estimated annual average hourly wage of $25 per hour for 2018.

*Cost were estimated through GLM Models with Gaussian Family and log link functions.

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Appendix 2. Results of Generalized Linear Models Estimating Caregiving Costs: Testing Sensitivity of Model Results to Caregiver Depression Status (Excluding Caregivers with Positive Depression Screening)

Variable Model n Coefficient

($ amount)

SE 95% CI

(lower, upper

p

Model 1: Total Indirect Costs 964

TRD (1) vs No TRD (0) 0.329

(2868.38) 0.060 0.211, 0.446 .0000

Age -0.049

(-598.79) 0.026 -0.100,

0.002 .0569

Male 0.331

(4185.07)

0.063 0.207, 0.454 .0000

White 0.029

( 423.51) 0.059 -0.087,

0.144 .6265

Part-time Job 0.223

(3388.50) 0.063 0.100, 0.347 .0004

Major Condition indicator 0.112

(1844.26) 0.059 -0.004,

0.227 .0591

TRD No TRD Difference Estimated indirect Cost of TRD vs.

No TRD*

10,239.84 7,371.46 2868.38 .0000

Model 2: Total Direct Costs 1055

TRD (1) vs No TRD (0) 0.346

(8164.27) 0.050 0.248, 0.444 .0000

Age -0.003

( -76.36) 0.021 -0.044,

0.038 .8954

Male -0.033

(-937.60) 0.056 -0.143,

0.076 .5525

White 0.467

(11763.28)

0.071 0.328, 0.606 .0000

Part-time Job -0.012

(-363.26) 0.055 -0.119,

0.096 .8325

Major Condition indicator 0.050

(1551.83) 0.051 -0.050,

0.150 .3246

TRD No TRD Difference Estimated Direct Cost of TRD vs. No

TRD* 27,939.84 19,775.57 8164.27 .0000

+ All costs are annualized and based on the United States Bureau of Labor Statistics estimated annual average hourly wage of $25 per hour for 2018.

*Cost were estimated through GLM Models with Gaussian Family and log link functions.

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Supplemental Digital Content

Appendix 3: Frequency of Providing Caregiving Assistance by Type Provided

Missing TRD No TRD p

Grooming, % (N) 43 .0000

Not at all 37.0 (60) 23.1 (231)

<1 a week 9.9 (16) 28.8 (287)

1-2 times a week 17.3 (28) 33.1 (330)

3-6 times a week 20.4 (33) 10.3 (103)

Every day 15.4 (25) 4.7 (47)

Administering/managing medications, % (N)

52 .0000

Not at all 22.8 (37) 14.4 (142)

<1 a week 9.3 (15) 27.6 (273)

1-2 times a week 15.4 (25) 33.9 (335)

3-6 times a week 14.2 (23) 12.0 (119)

Every day 38.3 (62) 12.1 (120)

Housework, % (N) 43 .0000

Not at all 23.5 (38) 8.5 (85)

<1 a week 14.8 (24) 34.3 (342)

1-2 times a week 22.2 (36) 39.1 (390)

3-6 times a week 12.3 (20) 8.3 (83)

Every day 27.2 (44) 9.8 (98)

Shopping, % (N) 47 .0000

Not at all 15.3 (25) 6.1 (61)

<1 a week 26.4 (43) 35.6 (354)

1-2 times a week 27.6 (45) 22.3 (221)

3-6 times a week 11.7 (19) 29.1 (289)

Every day 19.0 (31) 6.8 (68)

Preparing Meals, % (N) 48 .0000

Not at all 18.0 (29) 9.6 (95)

<1 a week 8.7 (14) 27.3 (271)

1-2 times a week 18.6 (30) 42.8 (425)

3-6 times a week 19.9 (32) 7.8 (78)

Every day 34.8 (56) 12.6 (125)

Transporting, % (N) 46

Not at all 22.2 (36) 12.1 (120) .0000

<1 a week 8.0 (13) 17.7 (176)

1-2 times a week 20.4 (33) 55.5 (552)

3-6 times a week 26.5 (43) 8.2 (82)

Every day 22.8 (37) 6.5 (65)

Managing finances, % (N) 44 .0000

Not at all 9.8 (16) 10.8 (108)

<1 a week 11.0 (18) 14.0 (139)

1-2 times a week 15.3 (25) 56.6 (564)

3-6 times a week 23.9 (39) 5.9 (59)

Every day 39.9 (65) 12.7 (126)

Providing encouragement, %

(N) 46 .0000

Not at all 11.7 (19) 12.2 (121)

<1 a week 34.6 (56) 36.0 (358)

1-2 times a week 27.2 (44) 15.0 (149)

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3-6 times a week 9.9 (16) 28.9 (288)

Every day 16.7 (27) 7.9 (79)

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