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Supplemental

Table 1. Demographic and clinical characteristics and risk behaviors at screening by enrollment status.

TDF2 clinical trial, Botswana 2007-2010.

Characteristic Total Screened (N=2532)

Screened and Not Enrolled (N=1331)

Screened and Enrolled

(N=1201) p-value Age (in years)

18-24 1450 (57.3) 771 (58.0) 679 (56.5) 0.0002

25-29 905 (35.7) 493 (37.0) 412 (34.3)

30-39 177 (7.0) 67 (5.0) 110 (9.2)

Gender

Female 1191 (47.0) 639 (48.0) 552 (46.0) 0.3027

Male 1341 (53.0) 692 (52.0) 649 (54.0)

Education

Primary or less 106 (4.2) 66 (5.0) 40 (3.3) 0.0006

Secondary (Jr/Sr) 1904 (75.2) 1026 (77.1) 878 (73.1) Post-secondary 522 (20.6) 239 (18.0) 283 (23.6) Screening Site

Gaborone 1155 (45.6) 515 (38.7) 640 (53.3) <0.0001

Francistown 1377 (54.4) 816 (61.3) 561 (46.7)

Marital Status

Married or Cohabitating 143 (5.7) 73 (5.5) 70 (5.8) 0.3647

Single 2383 (94.1) 1256 (94.4) 1127 (93.8)

Separated or Divorced 5 (0.2) 1 (0.1) 4 (0.3)

Missing 1 (0.04) 1 (0.1) 0 (0.0)

Occupational Status

Employed 914 (36.1) 441 (33.1) 473 (39.4) 0.0011

Unemployed 1618 (63.9) 890 (66.9) 728 (60.6)

HIV Status

Positive 198 (7.8) 198 (14.9) 0 (0.0) <0.0001

Negative 1896 (74.9) 695 (52.2) 1201 (100.0)

Not Indicated 2 (0.1) 2 (0.2) 0 (0.0)

Missing 436 (17.2) 436 (32.8) 0 (0.0)

Number of Lifetime Sexual Partners

0-1 151 (6.0) 103 (7.7) 48 (4.0) <0.0001

2+ 2240 (88.5) 1123 (84.4) 1117 (93.0)

Missing 141 (5.6) 105 (7.9) 36 (3.0)

Number of Different Partners in Last 3 Months

0 231 (9.1) 231 (17.4) 0 (0.0) <0.000

1 1668 (65.9) 819 (61.5) 849 (70.7)

2 422 (16.7) 196 (14.7) 226 (18.8)

3+ 205 (8.1) 79 (5.9) 126 (10.5)

Missing 6 (0.2) 6 (0.5) 0 (0.0

Number of Times of

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Vaginal Sex with

Different Partners in Last 3 Months

0 233 (9.2) 231 (17.4) 2 (0.2)

1 122 (4.8) 64 (4.8) 58 (4.8)

2 184 (7.3) 95 (7.1) 89 (7.4)

3+ 1606 (63.4) 718 (53.9) 888 (73.9)

Missing 387 (15.3) 223 (16.8) 164 (13.7) <0.0001

Used Condoms with Different Partners in the Last 3 Months

Yes 2085 (82.4) 987 (74.2) 1098 (91.4) <0.0001**

No 207 (8.2) 105 (7.9) 102 (8.5)

Missing 240 (9.5) 239 (18.0) 1 (0.1)

**If Missing values are excluded from the Chi-Square Test, the p-value becomes 0.3521

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