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Supplemental Digital Content for “National Trends in Readmission Following Inpatient Surgery in the Hospital Readmissions Reduction Program Era”

Winta T. Mehtsun MD MPH Irene Papanicolas PhD

Jie Zheng PhD E. John Orav PhD Keith D. Lillemoe MD Ashish K. Jha MD MPH

Contents

Supplemental Digital Content Table 1 Procedure ICD-9 Codes Included in Analysis Supplemental Digital Content Table 2 Characteristics of Medicare Patients Undergoing Targeted and Non-Targeted Surgical Procedures in 2005 and 2014

Supplemental Digital Content Table 3 Annual Change in Readmission Rates Among Medicare Beneficiaries in Pre-ACA, HRRP Implementation, and HRRP Penalty Era

Supplemental Digital Content Table 4 Procedure Specific National Readmission Trends

Among Medicare Beneficiaries in Pre-ACA, HRRP Implementation, and HRRP Penalty Era

Supplemental Digital Content Table 5 National Readmission Trends Among Medicare

Beneficiaries in Pre-ACA, HRRP Implementation, and HRRP Penalty Era Across Quartiles of

Baseline Readmission

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Supplemental Digital Content Table 1 Procedure ICD-9 Codes Included in Analysis

Procedure ICD-9 Procedure Code

Coronary artery bypass graft 3610, 3611, 3612, 3613, 3614, 3615, 3617, 3619 Abdominal aortic aneurysm repair 3864, 3834, 3844, 3973, 3971

Pulmonary lobe resection/segmentectomy 3241, 3249, 3230, 3239

Colorectal resection 1731-1736, 1739, 4503, 4526, 4541, 4549, 4571-4576, 4579, 4581, 4582, 4583

Hip replacement 8151, 8152

Appendectomy 4709, 4720, 4791, 4701

Cholecystectomy 5120, 5122, 5121, 5103, 5104, 5123, 5124

Knee replacement 8154

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Supplemental Digital Content Table 2 Characteristics of Medicare patients Undergoing Targeted and Non-Targeted Surgical Procedures in 2005 and 2014

Targeted Non-Targeted

2005 2014 2005 2014

(N=517,148) (N=458,456) (N=266,498) (N=182,821)

Index Admission Characteristics

Elective Admission (%) 70 78.6 47.5+ 47.4+

Length of Stay (days, median) 5 4 8 6

Discharge Location

Home (%) 19.7 20.9 63.3 60.4

Home with VNA (%) 26.0 34.0 15.7 17.3

Skilled nursing facility

(%) 30.2 32.5 15.1+ 15.3+

Rehabilitation Facility

(%) 21.1 10.2 2.5 2.9

Patient Characteristics

Age (year, median) + 75.1+ 75.0+ 75.4+ 75.7+

Male (%)+ 41.2 40.6 46.8 48.5

Non-white race (%)+ 8.8+ 8.2+ 11.4+ 12.0+

Hypertension (%) 65.5 67.7 54.2 57.2

Diabetes (%) 19.4 21.3 17.6 20.5

Renal Failure (%) 2.7 7.7 3.7 8.7

Liver Disease (%) 0.4 0.7 1.8 2.4

Obesity (%) 6.1 14.2 3.2 8.7

Hospital Characteristics

Hospital Size +

Small (%) 25.7 25.8 28.2 26.6

Medium (%) 61.0 60.4 59.1 59.9

Large (%) 13.4 13.8 12.7 13.4

Teaching Status+

Major Teaching (%) 9.0 9.1 8.6 9.0

Minor (%) 12.8 13.1 12.5 12.9

Non-Teaching (%) 78.2 77.8 78.9 78.1

Targeted procedures included CABG, hip replacement, and knee replacement. Non-targeted procedures include colectomy, pulmonary lobectomy, AAA repair, cholecystectomy, and appendectomy. All comparisons between targeted procedures in 2005 vs. 2014 and non-targeted procedures in 2005 vs. 2014 are significant at p<0.001 except those denoted with +, which where p>0.05.

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Supplemental Digital Content Table 3 Annual Change in Readmission Rates Among Medicare Beneficiaries in Pre-ACA, HRRP Implementation, and HRRP Penalty Era

Non-targeted Conditions Targeted Conditions All Conditions

-0.60% -0.50% -0.40% -0.30% -0.20% -0.10% 0.00% 0.10%

-0.51%

-0.03%

-0.23%

-0.41%

-0.53%

-0.52%

0.10%

-0.40%

-0.24%

HRRP Penalty Period Annual Risk Adjusted Change in Readmission RatesHRRP Implementation Period Pre-ACA Period

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Supplemental Digital Content Table 4 Procedure Specific National Readmission Trends Among Medicare Beneficiaries in Pre- ACA, HRRP Implementation, and HRRP Penalty Era

2005 Unadjusted Readmission

Rate

Pre-ACA Period HRRP Implementation Period HRRP Penalty Period (Q1 2005 – Q1 2010) (Q2 2010 – Q2 2012) (Q3 2012 – Q4 2014)

Quarterly Slope Quarterly Slope Change in slope

from Pre- ACA Quarterly Slope

Change in slope from implementation of

ACA

[95% CI] [95% CI] [95% CI] [95% CI] [95% CI]

Targeted Procedures

CABG 18.8% -0.078% -0.232% -0.155% -0.269% -0.036%

+

[-0.098, -0.058] [-0.275, -0.189] [-0.207, -0.102] [-0.318, -0.219] [-0.117, 0.044]

Hip Replacement 11.9% -0.104% -0.107% -0.00003

+ -0.105% 0.002%+

[-0.126, -0.083] [-0.131, -0.084] [-0.041, 0.035] [-0.128, -0.082] [-0.039, 0.044]

Knee Replacement 7.0% -0.075% -0.058% 0.00017

+ -0.075% -0.017%+

[-0.094, -0.056] [-0.074, -0.042] [-0.011, 0.046] [-0.090, -0.059] [-0.044, 0.010]

Non - Targeted Procedures

AAA Repair 13.0% 0.01%

+ -0.122% -0.131%* -0.151% -0.029%+

[-0.019, 0.038] [-0.182, -0.061] [-0.211, -0.051] [-0.224, -0.078] [-0.147, 0.089]

Lobectomy 13.3% -0.035%

* -0.04% -0.00001 -0.193% -0.157%*

[-0.068, -0.002] [-0.096, 0.024] [-0.085, 0.082] [-0.260, -0.126] [-0.271, -0.043]

Colectomy 15.0% 0.057% -0.093% -0.149% -0.102% -0.009%

+

[0.041, 0.072] [-0.127, -0.058] [-0.195, -0.104] [-0.145, -0.058] [-0.080, 0.061]

Appendectomy 10.1% 0.01%

+ -0.068%* -0.08%+ -0.05%+ 0.019%+

[-0.022, 0.038] [-0.131, -0.004] [-0.160, 0.010] [-0.129, 0.031] [-0.110, 0.147]

Cholecystectomy 12.8% 0.019%

* -0.134% -0.153%* -0.077% 0.056%+

[0.005, 0.033] [-0.165, -0.102] [-0.193, -0.112] [-0.117, -0.037] [-0.007, 0.12]

All comparisons are significant at p<0.001 except those denoted with *, which where 0.001< p <0.05, and +, which where p>0.05.

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Supplemental Digital Content Table 5 National Readmission Trends Among Medicare Beneficiaries in Pre-ACA, HRRP Implementation, and HRRP Penalty Era Across Quartiles of Baseline Readmission

Quartiles of Baseline Readmission Rates

Procedures

Pre-ACA Period HRRP Implementation Period HRRP Penalty Period

(Q1 2005 – Q1

2010) (Q2 2010 – Q2 2012) (Q3 2012 – Q4 2014)

Quarterly Slope [95% CI]

Quarterly Slope [95% CI]

Change in slope from Pre- ACA

[95% CI]

P-Value Quarterly Slope [95% CI]

Change in slope from implementation of

ACA [95% CI]

P-Value

Lowest Quartile (5.5%)a

Targeted

Procedures 0.005%+ -0.10% -0.10% <0.001 -0.08% 0.02%+ 0.45

[-0.01%, 0.02%] [-0.13%, -0.07%] [-0.14%, -0.07%] [-0.11%, -0.05%] [-0.03%, 0.07%]

Non - Targeted Procedures

0.11% -0.17% -0.28%

<0.001 -0.10%* 0.07%+

[0.09%, 0.14%] [-0.23%, -0.11%] [-0.36%, -0.20%] [-0.17%, -0.03%] [-0.05%, 0.18%] 0.25

2nd Quartile (12.6%)a

Targeted

Procedures 0.05% -0.14% -0.09% <0.001 -0.10% 0.04%+ 0.06

[-0.06%, -0.04%] [-0.16%, -0.11%] [-0.12%, -0.05%] [-0.12%, -0.07%] [-0.002%, 0.08%]

Non - Targeted Procedures

0.03%* -0.14% -0.17%

<0.001 -0.06%* 0.08%*

[0.01%, 0.04%] [-0.18%, -0.10%] [-0.22%, -0.12%] [-0.10%, -0.02%] [0.01%, 0.16%] 0.02

3rd Quartile (20.0%)a

Targeted

Procedures [-0.13%, -0.09%]-0.11% [-0.21%, -0.15%]-0.18% [-0.11%, -0.03%]-0.07% <0.001 [-0.15%, -0.10%]-0.13% [0.01%, 0.11%] 0.06%* 0.03 Non - Targeted

Procedures [-0.02%, 0.01%] -0.01%+ [-0.13%, -0.06%]-0.09% [-0.13%, -0.04%]-0.09% <0.001 [-0.15%, -0.05%]-0.10% [-0.08%, 0.07%]-0.01%+ 0.89

Highest Quartile (38.8)a

Targeted Procedures

-0.23% -0.07% 0.15%

<0.001 -0.14% -0.07%*

[-0.28%, -0.18%] [-0.11%, -0.04%] [0.08%, 0.22%] [-0.17%, -0.11%] [-0.12%, -0.01%] 0.02 Non - Targeted

Procedures [-0.02%, 0.02%]0.002%+ [-0.14%, -0.06%]-0.10% [-0.15%, -0.05%]-0.10% <0.001 [-0.17%, -0.06%]-0.12% [-0.10%, 0.07%]-0.02%+ 0.70 Targeted procedures include CABG, hip replacement, and knee replacement. Non-targeted procedures include colectomy, pulmonary lobectomy, AAA repair, cholecystectomy, and appendectomy.

All comparisons are significant at p<0.001 except those denoted with *, which where 0.001< p <0.05, and +, which where p>0.05.

a Mean readmission rate across hospitals in the given quartile in 2005.

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