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Three distinct eras of vaccine denialism have been detailed, with the third (current) era distinguished by the use of the Internet to spread anti-vaccination ideologies. However, scientific investigations and rigorous experiments to find the source of this immunity began in the late 18th century. At that time, several scientists, guided by evidence of the effect of microorganisms and non-living pathogens on disease, discovered the first method of creating attenuated forms of disease in the laboratory, rather than finding naturally occurring attenuated forms.

Because almost the entire U.S. population is vaccinated through these routine doctor visits (Centers for Disease Control, 2010), the population as a whole is afforded immunity because there are not enough unvaccinated individuals for an infection to develop and spread in a epidemic. If parents cannot provide proof of the child's vaccination or obtain an authorized exemption, the child cannot be enrolled. Having done this, analysis of a survey of University of Mississippi students provided a glimpse into the measurable, contemporary effects such movements had on students' views on vaccination.

Figure 1.1. Community Immunity ("Herd" Immunity) (National Institute of Allergy  and Infectious Diseases)
Figure 1.1. Community Immunity ("Herd" Immunity) (National Institute of Allergy and Infectious Diseases)

Literature Review Literature Review

By the end of the century, Jenner's work was published and his method of creating immunity, called "vaccination" after the name of the cowpox virus, vaccinia, spread worldwide (Pead, 2006). With these developments, the age of vaccination began to take shape with mass-produced smallpox vaccinations and the first vaccination programs in the late 19th and 20th centuries. One woman we vaccinated admitted that she had escaped vaccination during four previous visits from the Ministry of Health.

This power, and the limitations on it, laid the foundation for public health policy that would be made for the rest of the 20th century. With advances in technology at the end of the 19th century, vaccines became available against a growing number of diseases. Anti-vaccination literature of the period reflects a pervasive fear that the new vaccines and treatments—with all their unknown and unpleasant side effects—would be made mandatory.

These groups fought from the turn of the century until the 1920s, lobbying state legislatures and local governments to scale back state powers that forced citizens to receive vaccinations. However, as many vocal leaders of the movement began to die in the 1920s, vaccination rates began to rise again (Colgrove, 2006). He served as Governor of New York for one term and President of the United States for three terms while paralyzed from the waist down as a result of the infection (Fairchild, 2001).

Sabin's vaccine depended on a weakened form of poliovirus, while Salk used an inactivated form of the virus. Although an early shipment of the vaccine caused rare cases of paralysis due to improper activation, belief in the vaccine remained strong: less than 1 percent of New York City parents refused to vaccinate their children (Colgrove, 2006; Cutler, 1955). Regardless of the source of the failures, policymakers across the country began to consider whether the lack of mandatory vaccination laws in many states was detrimental to forced vaccination programs relying solely on persuasion and marketing.

By 1986, the cost of the vaccine had risen from ten cents to three dollars, and the annual number of lawsuits against its manufacturers had exploded from two to 250 (Colgrove, 2006; Freed, Katz, & Clark, 1996; United States, 1987). ). The first period began with the development of the first vaccine at the end of the 18th century and continued until the middle of the 19th century, with many conflicts regarding the uncertain long-term effects of vaccination and the legal consequences of mandatory vaccination. Against this historical background, it is important to evaluate today's beliefs about vaccines.

Figure 2.1. The Cow-Pock-or-the Wonderful Effects of the New Inoculation!-  (Gillray)
Figure 2.1. The Cow-Pock-or-the Wonderful Effects of the New Inoculation!- (Gillray)

Methodology

The research was largely based on a questionnaire published in the report of the World Health Organization (WHO) SAGE task force on vaccine hesitancy. This report, published in November 2014, details the findings and recommendations of the World Health Organization's Strategic Advisory Group of Experts on Immunization (SAGE) on measuring and combating vaccine hesitancy, a term the group described as “(for) delay in acceptance or refusal vaccines. despite the availability of vaccination services." This group, composed of public health experts from around the world, developed a. Because of variables in socioeconomic conditions in different regions, the group recommended that specific questions and the order of questions be changed.

I designed my survey using Qualtrics survey software licensed by the University of Mississippi and hosted on the Qualtrics website. Skip logic was used to prevent respondents who indicated they were under 18 years of age and/or were not a student at the University of Mississippi from completing the survey. Because the survey was offered online, potential respondents were solicited through their University of Mississippi student email accounts.

The sample was randomly selected and stratified by gender, ethnicity, and academic classification to be representative of the University of Mississippi student population. The survey was sent by email on September 15, 2015, and a reminder email was sent eight days later on September 23. 384 responses were received and 69 responses were removed because they were incomplete or because respondents indicated they were under 18 years of age, not a student, or a graduate student.

The cross-tabulation function of the software was used to provide both descriptive statistics (univariate and bivariate) and chi-square tests. Chi-square tests were similarly used to analyze the significance of responses by demographic category and of responses to individual questions.

Results and Analysis

Question  6:  What  is  your  academic  classi5ication?

Question  4:  What  category  does  your  major  fall   under?

90.8% of respondents answered yes to the question, do you think childhood vaccinations are safe? When asked if they "believe the benefits of childhood vaccination outweigh any risks," 87% said "yes." 23.9% of respondents said "yes" when asked if they "believe(d) that there are other, better ways to prevent vaccine-preventable diseases than with a vaccine." When asked if they "believe(d) that some vaccines could cause autism in children," 22.6% answered "yes." When they were asked an additional question to give one reason why they had or would consider it, 44.7% of this group said they would do so if they thought the vaccine was unnecessary, 13.5% if considered the vaccine unsafe, 10.4%. % if they think the vaccine is not effective, 6.7% due to a negative experience with previous vaccination, 5.5% if they could not afford the vaccination, a further 5.5% if they read or heard negative media about vaccination, 4 .3% because they knew someone who had a reaction to a vaccination, 4.3%.

Similar results were found when respondents were asked if they would ever not vaccinate their child. When asked a follow-up question about why they did or would consider doing this, 37.9% responded that they would do this or might do this if they believed the vaccination was not safe, 27.3% if they believed the vaccine was not necessary, and 9.1% if their child had previously had a reaction to the vaccination, 6.8% if they had heard or read about it. 3% if they knew someone who had a reaction to the vaccine, 2.3% because they don't believe in vaccination, 1.5% told someone the vaccine was unsafe, 0.6% if their child was allergic to something in it vaccine, and 2.3% had multiple reasons (see Figure 5.4).

As with the similar question about reasons why respondents would refuse vaccination for themselves, no respondents indicated that they were religiously opposed to vaccination.

Question  21:  Why  have  you  or  would  you   refuse  a  vaccination  for  yourself?

Results for and the text for the second part of questions can be found in the following tables (see tables 5.2-5.4). All responses were given a value of 1-5, with "Strongly Disagree" assigned a value of 1 and "Strongly Agree" assigned a value of 5.

Question  23:  Why  have  you  or  would  you   refuse  a  vaccination  for  your  child?

Almost no statistically significant (p-value < 0.05) p-values ​​were found when testing the responses to the individual demographic question with the two parts of the questions that made up the rest of the survey. In order to obtain such results, all questions of the first part of the survey, except for questions 18, 21 and 23, were tested with all questions of the first and second part. Looking at Tables 5.5, it is apparent that questions 28, 36 and 37 are exceptions to the network of relationships formed by the questions in both parts of the survey.

Such low means indicate extremely high rates of "strongly disagree" and "disagree," which is indicative of relatively homogeneous beliefs regardless of respondents' answers to other questions. Like the analysis of the first set of survey questions, question 28 was an exception to the relationships shown by the other questions due to question 28's high level of responses indicating "neither agree nor disagree" and mean value of 2.81. There are four major findings from the literature review and study of the University of Mississippi campus.

The third era began in the middle of the 20th century and has continued to the present day. Results from the survey showed that the sample of University of Mississippi students was more pro-vaccine than national population surveys. The survey results also showed a strong correlation between anti-vaccine responses to questions in both sections of the survey.

Additionally, further survey research on University of Mississippi student beliefs about vaccines could potentially benefit from an expanded section on respondent demographics. With so many places showing the effects of the burgeoning anti-vaccination movement, the greatest potential to prevent further declines in vaccination rates is challenging the exemption laws that allow children to remain unvaccinated. Smallpox: Defeating Death's Most Dreaded Minister,” Annals of Internal Medicine 127, no.

Davidovitch, N., "Negotiating Disagreement: Homeopathy and Anti-Vaccination at the Turn of the Twentieth Century," in The Politics of Healing, 11-28. 34; Community-wide Use of Oral Poliovirus Vaccine: Effectiveness of the Cincinnati Program." American Journal of Diseases of Children. Childhood Immunization Program: Hearing before the Subcommittee on Health and the Environment of the Committee on Energy and Commerce, House of Representatives, One Hundredth Congress , first session, 11 March 1987.

Table 5.2. Survey Questions Part 2.1
Table 5.2. Survey Questions Part 2.1

Gambar

Figure 1.1. Community Immunity (&#34;Herd&#34; Immunity) (National Institute of Allergy  and Infectious Diseases)
Figure 1.2. State Non-Medical Exemptions from School Immunization Requirements,  2015 (National Conference of State Legislatures)
Figure 2.1. The Cow-Pock-or-the Wonderful Effects of the New Inoculation!-  (Gillray)
Table 5.1. Survey Questions Part 1  1. Are you at least 18 years of age?
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