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Appendix

We conducted a systematic review of papers to determine robotic TKA failure rates to derive an annualized failure rate for robotic TKA revision.

Figure X. Flow diagram presenting the systematic review process used in this study for robotic total knee arthroplasty studies

Studies included in analysis (n = 11 )

Full-text articles excluded Computer-assisted

navigation (n =10) Follow-up less than 1 year

(n=12)

IncludedEligibilityScreeningIdentfcaton

Full-text articles assessed for eligibility

(n = 33 )

Records excluded (n = 278 ) Records screened

(n = 311 )

Records after duplicates removed (n =311)

Records identified through database searching

(n =311)

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Table detailing the studies from the systematic review used to derive robotic- assisted TKA revision rates

Studies Year Age F/u

(years)

Sample size System TKA revisions

Park et al 2007 63 3.5 32 ROBODO

C

0

Song et al 2011 67 1 30 ROBODO

C

0

Kim et al 2016 38 5 32 ROBODO

C

2 septic

Liow et al 2017 - 2 31 ROBODO

C

2 (1 septic, 1 aseptic)

Yang et al 2017 66 10 71 ROBODO

C

2

Cho et al 2019 68 11 155 ROBODO

C

2 (both septic)

Marchand et al 2019 65 1 53 MAKO 0

Jeon et al 2019 84 10 84 ROBODO

C

1 aseptic

Smith et al 2019 68 1 120 MAKO 0

Malkani et al 2019 - 2 188 MAKO 2 aseptic

Kim et al 2020 60 13 674 ROBODO

C

15 (all aseptic)

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Scatterplot depicting the total costs and QALYs of the 10,000 iterative simulations of the probabilistic sensitivity analysis where the model’s sensitive parameters are varied across distributions: QOL of a robotic-assisted TKA at 1-year and >1 year, the QOL of a conventional TKA at 1-year and >1 year, the probability of early (≤1 year) and late (>1 year) conventional TKA failure, the probability of early (≤1 year) and late (>1 year) robotic-assisted TKA failure, the QOL of an optimal TKA, and the annualized total per-case cost of robotic-assistance.

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