SEARCH STRATEGIES
OVID MEDLINE:
1. Traumatic brain injury.mp or exp. Brain injuries, Traumatic 2. Limit 1 to (English language and humans)
3. Exp. Head injuries, Closed/ Or Head injur*.mp or exp Head Injuries, Penetrating/ Or exp Brain Injuries/
4. Limit 3 to (English language and humans)
5. Intracranial pressure.mp or exp Intracranial pressure/
6. Limit 5 to (English language and humans)
7. Exp Intracranial Pressure/ or ICP.mp or exp Brain injuries, Traumatic/ or exp Intracranial Hypertension/ or exp Brain Injuries/
8. Limit 7 to (English language and humans) 9. 2 or 4 or 6 or 8 = 85811 results
10. Exp Deep Sedation or Sedation.mp
11. Limit 10 to (English language and humans) 12. Sedat*.mp
13. Limit 12 to (English language and humans)
14. exp "Hypnotics and Sedatives"/ or Propofol.mp. or exp Propofol/ or exp Anesthesia, Intravenous/ or exp Anesthetics, Intravenous/
15. Limit 14 to (English language and humans) 16. Midazolam.mp or exp Midazolam/
17. Limit 16 to (English language and humans) 18. Ketamine.mp or exp Ketamine/
19. Limit 18 to (English language and humans) 20. Opiates.mp or exp Opiate Alkaloids/
21. Limit 20 to (English language and humans)
22. Dexmedetomidine.mp. or exp Dexmedetomidine/ or exp Adrenergic alpha-Agonists/
23. Limit 22 to (English language and humans)
24. 11 or 13 or 15 or 17 or 19 or 21 or 23 = 145029 results 25. 9 and 24 = 1759 results
26. Limit 25 to (“all adult (19 plus years)” and clinical trial = 183 results (13.07.2021)
OVID Embase:
1. Traumatic brain injury.mp or exp. Brain injuries, Traumatic 2. Limit 1 to (English language and humans)
3. Exp. Head injuries, Closed/ Or Head injur*.mp or exp Head Injuries, Penetrating/ Or exp Brain Injuries/
4. Limit 3 to (English language and humans)
5. Intracranial pressure.mp or exp Intracranial pressure/
6. Limit 5 to (English language and humans)
7. Exp Intracranial Pressure/ or ICP.mp or exp Brain injuries, Traumatic/ or exp Intracranial Hypertension/ or exp Brain Injuries/
8. Limit 7 to (English language and humans) 9. 2 or 4 or 6 or 8 = 241476 results
10. Sedation.mp or exp deep sedation/ or exp sedation/
11. Limit 10 to (human and English language)
12. exp propofol/ or exp sedation/ or Sedat*.mp. or exp sedative agent/ or exp ketamine/
13. Limit 12 to (human and English language) 14. Propofol.mp or exp propofol/
15. Limit 14 to (human and English language) 16. Exp midazolam/ or Midazolam.mp.
17. Limit 16 to (human and English language) 18. Ketamine.mp or exp ketamine/
19. Limit 18 to (human and English language)
20. Opiates.mp. or exp opiate/ or exp mu opiate receptor agonist/ or exp opiate agonist/
21. Limit 20 to (human and English language)
22. Dexmedetomidine.mp. or exp dexmedetomidine/
23. Limit 22 to (human and English language)
24. 11 or 13 or 15 or 17 or 19 or 21 or 23 = 365830 results 25. 9 and 24 = 8549 results
26. limit 25 to (clinical trial and adult <18 to 64 years>) = 241 results (13.07.2021)
Pubmed – 13.07.2021
Search: ((((((Sedat*) OR (Propofol)) OR (Opia*)) OR (Midazolam)) OR (Dexmedetomidine)) OR (Ketamine) AND ((clinicaltrial[Filter]) AND
(humans[Filter]) AND (english[Filter]) AND (alladult[Filter]))) AND ((((Traumatic brain injury) OR (Head injur*)) OR (intracranial pressure)) OR (ICP) AND
((clinicaltrial[Filter]) AND (humans[Filter]) AND (english[Filter]) AND (alladult[Filter]))) Filters: Clinical Trial, Humans, English, Adult: 19+ years (("sedat*"[All Fields] OR ("propofol"[MeSH Terms] OR "propofol"[All Fields] OR
"propofol s"[All Fields]) OR "opia*"[All Fields] OR ("midazolam"[MeSH Terms] OR
"midazolam"[All Fields] OR "midazolam s"[All Fields] OR "midazolame"[All Fields]) OR ("dexmedetomidine"[MeSH Terms] OR "dexmedetomidine"[All Fields] OR
"dexmedetomidine s"[All Fields]) OR ("esketamine"[Supplementary Concept] OR
"esketamine"[All Fields] OR "ketamine"[All Fields] OR "ketamine"[MeSH Terms] OR
"ketamin"[All Fields] OR "ketamine s"[All Fields] OR "ketamines"[All Fields])) AND ("clinical trial"[Publication Type] AND "humans"[MeSH Terms] AND
"english"[Language] AND "adult"[MeSH Terms]) AND (("brain injuries,
traumatic"[MeSH Terms] OR ("brain"[All Fields] AND "injuries"[All Fields] AND
"traumatic"[All Fields]) OR "traumatic brain injuries"[All Fields] OR ("traumatic"[All Fields] AND "brain"[All Fields] AND "injury"[All Fields]) OR "traumatic brain injury"[All Fields] OR (("head"[MeSH Terms] OR "head"[All Fields]) AND "injur*"[All Fields]) OR ("intracranial pressure"[MeSH Terms] OR ("intracranial"[All Fields] AND "pressure"[All Fields]) OR "intracranial pressure"[All Fields]) OR "ICP"[All Fields]) AND ("clinical trial"[Publication Type] AND "humans"[MeSH Terms] AND "english"[Language] AND
"adult"[MeSH Terms]))) AND ((clinicaltrial[Filter]) AND (humans[Filter]) AND (english[Filter]) AND (alladult[Filter]))
Translations
Propofol: "propofol"[MeSH Terms] OR "propofol"[All Fields] OR "propofol's"[All Fields]
Midazolam: "midazolam"[MeSH Terms] OR "midazolam"[All Fields] OR
"midazolam's"[All Fields] OR "midazolame"[All Fields]
Dexmedetomidine: "dexmedetomidine"[MeSH Terms] OR "dexmedetomidine"[All Fields] OR "dexmedetomidine's"[All Fields]
Ketamine: "Esketamine"[Supplementary Concept] OR "Esketamine"[All Fields] OR
"ketamine"[All Fields] OR "ketamine"[MeSH Terms] OR "ketamin"[All Fields] OR
"ketamine's"[All Fields] OR "ketamines"[All Fields]
clinicaltrial[Filter]: clinical trial [PT]
humans[Filter]: humans[MH]
english[Filter]: english [LA]
alladult[Filter]: adult[MH]
Traumatic brain injury: "brain injuries, traumatic"[MeSH Terms] OR ("brain"[All Fields] AND "injuries"[All Fields] AND "traumatic"[All Fields]) OR "traumatic brain injuries"[All Fields] OR ("traumatic"[All Fields] AND "brain"[All Fields] AND "injury"[All Fields]) OR "traumatic brain injury"[All Fields]
Head: "head"[MeSH Terms] OR "head"[All Fields]
intracranial pressure: "intracranial pressure"[MeSH Terms] OR ("intracranial"[All Fields] AND "pressure"[All Fields]) OR "intracranial pressure"[All Fields]
clinicaltrial[Filter]: clinical trial [PT]
humans[Filter]: humans[MH]
english[Filter]: english [LA]
alladult[Filter]: adult[MH]
=170 results
