Table S4. Sensitivity analysis of the definition of ‘high-risk’ cohort used in stratified analyses and meta-regression of the HIV incidence rate during pregnancy and breastfeeding
* Models were adjusted for region, length of study implementation, and calendar time.
Stratum Specific Estimates Univariate Meta-Regression Multivariate Meta-Regression*
Variable
Number of Estimates
Pooled incidence rate
(95% PI)
Ratio of the pooled incidence rate
(95% CI) P-value Omnibus p-value
Ratio of the pooled incidence rate
(95% CI) P-value Omnibus p-value
Study population comprised primarily of women in HIV- serodiscordant relationships
No 33 3.5 (1.4, 10.6) 1.0 - - - 1.0 - - -
Yes 2 7.4 (1.9, 29.2) 2.1 (0.9, 5.0) 0.09 0.09 4.7 (2.2, 10.2) <0.001 <0.001
Study population comprised
primarily of female sex workers
No 33 3.7 (1.2, 11.7) 1.0 - - - 1.0 - - -
Yes 2 2.2 (0.5, 9.7) 0.6 (0.2, 1.6) 0.3 0.3 0.6 (0.2, 1.8) 0.3 0.3
