Appendix 1: Physical Function Test Characteristics
Outcome Measure
Author/Year/Location Subjects
(n)
Age/Gende r
(mean ± SD)
Setting Severity Score
ICU LOS
(Median/IQR) Physical
Function in Intensive Care
Unit (PFIT) and scored
(PFITs)
Skinner et al,23 2009 Australia
10-12 56.8 (± 12.5) 7 males
Med-Surg, ICU and Resp
wean unit
APACHE II 10-25 (6 missing)
Not reported
Denehy et al,24 2013 Australia
116 59.3 (± 15.4) 60% male
ICU APACHE II
18.8 (6.0)
7 (6-11) Nordon-Craft et al,25 2014
USA
34-39 50.5 (±16.3) 63% male
ICU APACHE II
18.2 (5.5)
20 (12-26) Parry et al,26 2015
Australia
66 58 (±17)
M/F not reported
Mixed ICU APACHE II 21 (±7)
8 (5-15)
Chelsea Critical Care
Physical Assessment
Tool (CPAx)
Corner et al,27 2013 33 67 (51-75) M/F 25/8
General and Trauma ICU
APACHE II 20 (6)
Not reported Corner et al,28 2015
England
30 47.1 (±21.2) 63.3% male
Burn ICU BOBI score 4 (2.1)
17 (2-94) Corner et al,29 2014
England
499 62.3 (18.31) M/F not reported
Mixed Med- Surg ICU
APACHE II 16 (10-20)
6 (4-12)
Perme ICU Mobility
Score
Perme et al,30 2014 USA
35 67 (26-92)
60% male
CV ICU APACHE II 20 (7-31)
6 (1-24) Nawa et al,31 2014
USA
20 64.5 (20-86) 60% male
CV ICU APACHE II 16.5 (7-30)
4 (1-42) Surgical
Intensive Care Unit Optimal Mobilization Score (SOMS)
Kasotakis et al,33 2012 USA
113 60.2 (18-93) 58.4% male
Surgical ICU APACHE II 15.68 (3-32)
5.21 (1-31) Schaller et al,34 2016
Germany
128 Non-
neurocritical 63 (24-89)
68% male Neurocritical
61 (21-90)
Surgical ICU Not reported Not reported
61% male Piva et al,35 2015
Italy
98 61.5 (SD 16.4) 68.3% male
General and Neuro ICU
SAPS II 41.1 (15.7)
8 (4-13.5) Garzon-Serrano et al,32 2011
USA
63 RN group
58 (± 15) 66% male
PT group 58 (± 15) 66% male
Surgical ICU RN group APACHE II
9 ± 8 PT group APACHE II
12 ± 12
Not reported
ICU Mobility Scale (IMS)
Tipping et al,36 2016 Australia and New Zealand
192 58 (±15.8)
61% male
Mixed ICU APACHE II 19.1 (SD 7.6)
11 (6-17) Hodgson et al,37 2014
Australia
100 58 (±17)
38% male
Mixed Med- Surg and Trauma ICU
APACHE II 19 (±7)
Not reported
Parry et al,26 2015 Australia
66 58 (±17)
61% male
Mixed ICU APACHE II 21 (±7)
8 (5-15) Functional
Status Score for the ICU
(FSS-ICU)
Ragavan et al,38 2016 USA
26 53.65 (24-88) 46.2% male
Mixed ICU Not reported 4.04 (1-24)
Parry et al,26 2015 Australia
66 58 (±17)
61% male
Mixed ICU APACHE II 21 (±7)
8 (5-15) Acute Care
Index of Function (ACIF)
Bissett et al,39 2016 Australia
42 59 (16-88)
74% male
Mixed Med- Surg ICU
APACHE II 19 (±7)
19 (2-119)
De-Morton Mobility
Index (DEMMI)
Sommers et al, 2016 Netherlands
115 61 (±16.1)
67% male
Mixed Med- Surg ICU
APACHE II 15.2 (4.8) SOFA score
7 (3.6)
Not reported
Short Physical Performance
Battery (SPPB)
Parry et al,26 2015 Australia
(66) But only n = 23 for
SPPB
58 (±17) 61% male
Mixed ICU APACHE II 21 (±7)
8 (5-15)
Early Functional Abilities Scale
(EFA)
Alvsåker et al,41 2011 Norway
24 25 (20-37)
79% male
Trauma and Surgical ICU.
Specific TBI patients
Not reported 15 (9-19)
Functional Capacity Scale
(FCS)
Ślusarz et al,42 2012 Poland
97 51 (±14)
33.6% male
Surgical ICU.
Specific intracranial
aneurysm
Hunt and Hess Scale
Not reported
Ślusarz et al,43 2014 Poland
23 Age 21-40
(17.4%) Age 41-60
(52.2%) Age > 60
(30.4%) 39.1% male
overall
Surgical ICU.
Specific intracranial
aneurysm
Hunt and Hess Scale
Not reported
Ślusarz,44 2007 Poland
46 50.4 (±16.8) 50% male
Surgical ICU Specific for
brain neoplasm
surgery
Not reported Not reported
Ślusarz et al,45 2014 Poland
159 Male average age: 55 Female average
age 64 71.7% male
ICU specific for TBI
Not reported Not reported
Medical Research Council Sum Score (MRC- SS) and Hand
Held Dynamometr
y (HHD)
Hermans et al,46 2012 Belgium
MRC-SS: 75 HHD: 46
MRC-SS 59 (52-71) 50.7% male
HHD
*(47-68) 58.7% male
Surgical and Medical ICU
Not reported MRC-SS 22 (15-30)
HHD 15 (9-32)
Hough et al,47 2011 USA
30 (only 10 in
49 ±15 71% male
ICU Not reported Not Reported
ICU) Connolly et al,48 2013
England
For Reliability 20 For Predictive
49-65
For Reliability 67.5 (51.8-75)
12 males For Predictive 66.0 (54.8-76.3)
64 males
Mixed Med- Surg ICU
Reliability APACHE II 19.5 (15.5-
24.0) Predictive
APACHE II 17.0 (15.0-
22.0)
Reliability 33.5 (25.5-58)
Predictive 11.0 (6.0-25.3)
Ali et al,49 2008 USA
For Predictive 136 For Reliability
12
57.7 (± 15.5) 47.8% male
Medical ICU APACHE III 65.8 (±27)
SOFA 6.4 (±3.0)
ICUAP 21 (±11) No ICUAP
12 (±6) Baldwin et al,50 2013
Australia
17 78 (46-82)
59% male
ICU APACHE II
20 (5) SOFA 2(2)
18 (12-21)
Vanpee et al,51 2011 Belgium
39 64 (53-72)
62% male
Med-Surg ICU
Not reported Not reported Lee et al,52 2012
USA
95 61.2 (18.3)
59% male
Surg ICU APACHE II 15.2 (9.0)
5 (3-9.5) Functional
Assessment for Burns
(FAB)
Smailes et al,53 2013 United Kingdom
56 38.6 (34.3-43) M/F not reported
Burns ICU TBSA
35% (30-45)
12 (7-19.65)
KEY: *article records a 4 for median age of patient’s but reports IQR or (47-68).
Number of subjects discrepancy: Some authors used a different number of subjects for the psychometric testing, this has been noted
Abbreviations: Med = medical, Surg = surgical, APACHE = Acute Physiology and Chronic Health Evaluation, SOFA = Sequential Organ Failure Assessment, TBSA = Total Burn Surface Area, ICUAP = ICU Acquired Weakness, CV ICU = cardiovascular ICU