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Supplemental Digital Content - Appendix 1.
Sensitivity analyses for Kaplan-Meier “failure” plots of time from the start of antenatal care to ART initiation before delivery.
The plots below parallel those shown in Figure 3, with ART initiation shown by service delivery model for (A) all HIV-infected pregnant women, (B) for ART-eligible women (as defined by the service delivery model), and (C) for women with CD4 cell counts ≤350 cells/µl. Two sets of plots are shown: (i) plots excluding the first two months of observation under each service delivery model (labelled A.i, B.i and C.i, respectively) and (ii) plots restricted to the first 6 months of observation under each period (labelled A.ii, B.ii and C.ii, respectively).
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A.i. All HIV-infected women, excluding first 2 months of observation under each model of service delivery
B.i. ART-eligible women, excluding first 2 months of observation under each model of service delivery
C.i. Women with CD4 ≤350 cells/µl, excluding first 2 months of observation under each model of service delivery
0.000.200.400.600.801.00
Probability of ART initiation before delivery
0 30 60 90 120 150 180 210
Days after first antenatal clinic visit
Pre-intervention: CD4<200 Pre-intervention: CD4<350
Enhanced linkage Integrated ANC-ART
On-site CD4 testing Universal ART
0.000.200.400.600.801.00
Probability of ART initiation before delivery
0 30 60 90 120 150 180 210
Days after first antenatal clinic visit
Pre-intervention: CD4<200 Pre-intervention: CD4<350
Enhanced linkage Integrated ANC-ART
On-site CD4 testing Universal ART
0.000.200.400.600.801.00
Probability of ART initiation before delivery
0 30 60 90 120 150 180 210
Days after first antenatal clinic visit
Pre-intervention: CD4<200 Pre-intervention: CD4<350
Enhanced linkage Integrated ANC-ART
On-site CD4 testing Universal ART
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A.ii. All HIV-infected women, limited to the first 6 months of observation under each model of service delivery
B.ii. ART-eligible women, limited to the first 6 months of observation under each model of service delivery
C.ii. Women with CD4 ≤350 cells/µl, limited to the first 6 months of observation under each model of service delivery
0.000.200.400.600.801.00
Probability of ART initiation before delivery
0 30 60 90 120 150 180 210
Days after first antenatal clinic visit
Pre-intervention: CD4<200 Pre-intervention: CD4<350
Enhanced linkage Integrated ANC-ART
On-site CD4 testing Universal ART
0.000.200.400.600.801.00
Probability of ART initiation before delivery
0 30 60 90 120 150 180 210
Days after first antenatal clinic visit
Pre-intervention: CD4<200 Pre-intervention: CD4<350
Enhanced linkage Integrated ANC-ART
On-site CD4 testing Universal ART
0.000.200.400.600.801.00
Probability of ART initiation before delivery
0 30 60 90 120 150 180 210
Days after first antenatal clinic visit
Pre-intervention: CD4<200 Pre-intervention: CD4<350
Enhanced linkage Integrated ANC-ART
On-site CD4 testing Universal ART